S-phenyl (2R)-2-methylcyclopropane-1-carbothioate

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯硫酚酯
• 英文名称: S-phenyl (2R)-2-methylcyclopropane-1-carbothioate
• 化学式: C₁₁H₁₂OS
• 分子量: 192.28
• InChiKey: VJZYLITWEUNRDW-HNHGDDPOSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.1
• 重原子数：
  13
• 可旋转键数：
  3
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.36
• 拓扑面积：
  42.4
• 氢给体数：
  0
• 氢受体数：
  2

文献信息

• Adeno-associated virus (AAV) clades, sequences, vectors containing same, and uses thereof
  申请人：The Trustees of The University of Pennsylvania

  公开号：EP2292779B1

  公开（公告）日：2016-11-16
• MULTIMERIC IL-15 SOLUBLE FUSION MOLECULES AND METHODS OF MAKING AND USING SAME
  申请人：Altor Bioscience Corporation

  公开号：US20140134128A1

  公开（公告）日：2014-05-15

  The present invention features compositions and methods featuring ALT-803, a complex of an interleukin-15 (IL-15) superagonist mutant and a dimeric IL-15 receptor α/Fc fusion protein useful for enhancing an immune response against a neoplasia (e.g., multiple myeloma, melanoma, lymphoma) or a viral infection (e.g., human immunodeficiency virus).