摩熵化学
数据库官网
小程序
打开微信扫一扫
首页 分子通 化学资讯 化学百科 反应查询 关于我们
请输入关键词
历史搜索
    热门化合物HOT
    • 喹啉
    • 水杨醛
    • 二溴甲烷
    • 谷胱甘肽
    • L-乳酸
    • 苯巴比妥
    • 辣椒碱
    • 非那明
    • 百草枯
    • 联苯烯
    首页 分子通 (7R)-7-(2,4,5-trifluorophenyl)-6,7,8,9-tetrahydropyrido[1,2-a]benzimidazole-3-carbonitrile

    (7R)-7-(2,4,5-trifluorophenyl)-6,7,8,9-tetrahydropyrido[1,2-a]benzimidazole-3-carbonitrile

    分子结构分类

    有机化合物 - 有机杂环化合物 - 咪唑并[1，2-a]吡啶
    中文名称
    ——
    中文别名
    ——
    英文名称
    (7R)-7-(2,4,5-trifluorophenyl)-6,7,8,9-tetrahydropyrido[1,2-a]benzimidazole-3-carbonitrile
    英文别名
    ——
    (7R)-7-(2,4,5-trifluorophenyl)-6,7,8,9-tetrahydropyrido[1,2-a]benzimidazole-3-carbonitrile化学式
    CAS
    ——
    化学式
    C18H12F3N3
    mdl
    ——
    分子量
    327.3
    InChiKey
    JEHXLFWFEILCHT-LLVKDONJSA-N
    BEILSTEIN
    ——
    EINECS
    ——
    • 物化性质
    • 计算性质
    • ADMET
    • 安全信息
    • SDS
    • 制备方法与用途
    • 上下游信息
    • 反应信息
    • 文献信息
    • 表征谱图
    • 同类化合物
    • 相关功能分类
    • 相关结构分类

    计算性质

    • 辛醇/水分配系数(LogP)：
      4.3
    • 重原子数：
      24
    • 可旋转键数：
      1
    • 环数：
      4.0
    • sp3杂化的碳原子比例：
      0.22
    • 拓扑面积：
      41.1
    • 氢给体数：
      0
    • 氢受体数：
      5

    文献信息

    • [EN] CERTAIN DIPEPTIDYL PEPTIDASE INHIBITORS<br/>[FR] CERTAINS INHIBITEURS DE LA DIPEPTIDYL PEPTIDASE
      申请人：SHANGHAI FOCHON PHARMACEUTICAL CO LTD
      公开号：WO2014075317A1
      公开（公告）日：2014-05-22
      Provided are certain dipeptidyl peptidase inhibitors, pharmaceutical compositions thereof, and methods of use therefor.
      所提供的是某些二肽基肽酶抑制剂，其药物组成和使用方法。
    查看更多

    同类化合物

    3H-1,4,8B-三氮杂苊烯e-3,5(4H)-二酮 3,4-bis(hydroxymethyl)dipyrido[1,2-a;3',4'-d]imidazole 3-methyldipyrido[1,2-a;3',4'-d]imidazole 2-methyl-6,7,8,9-tetrahydropyrido<1,2-a>benzimidazole 6,7,8,9-tetrahydrobenzo[4,5] imidazo[1,2-a]pyridin-3-amine 3-bromo-6,7,8,9-tetrahydrobenzo[4,5]imidazo[1,2-a]pyridine N-[1-[3-(3-cyanophenyloxy)propan-1-yl]piperidin-4-yl]-5-thia-1,8b-diazaacenaphthylene-4-carboxamide N-[1-[3-(2-cyanophenyloxy)propan-1-yl]piperidin-4-yl]-5-thia-1,8b-diazaacenaphthylene-4-carboxamide 4,5-dihydro-4-[4-(tert-butoxycarbonylamino)butan-1-yl]-3H-1,4,8b-triazaacenaphthylene-3,5-dione diethyl 5-hydroxy-3-thia-1,8b-diazaacenaphthylene-2,4-dicarboxylate 5-thia-1,8b-diazaacenaphthylene-4-carbaldehyde 2-bromo-7,8-dihydrobenzo[4,5]imidazo[1,2-a]pyridin-9(6H)-one 2-(2-morpholinopyrimidin-5-yl)-7,8-dihydrobenzo[4,5]imidazo[1,2-a]pyridin-9(6H)-one 9H-imidazo[1,2-a]pyrrolo[2,3-c]pyridine 8-chloro-1-[2-(difluoromethoxy)phenyl]-3,4-dihydro-1H-pyrano[4',3':4,5]imidazo[1,2-a]pyridine 6-methoxymethyl-2,3-dimethyl-9-phenyl-7,8,9,10-tetrahydro-imidazo[2,1-a]isoquinoline 4,5-dihydro-4-(tert-butoxycarbonyl)-3H-1,4,8b-triazaacenaphthylen-3-one imidazo<4',5':4,5>imidazo<1,2-a>pyridine">1,10-diethylpyrido<1",2":1',2'>imidazo<4',5':4,5>imidazo<1,2-a>pyridine imidazo<4',5':4,5>imidazo<1,2-a>pyridine">1,10-dimethylpyrido<1",2":1',2'>imidazo<4',5':4,5>imidazo<1,2-a>pyridine 1,3,4-trifluoro-dipyrido[1,2-a;3',4'-d]imidazole 3-(cyclopropyl)pyrano[3',4':4,5]imidazo[1,2-a]pyridinone 3-[(N-benzyl-N-methylamino)methyl]pyrano-[3',4':4,5]imidazo[1,2-a]pyridin-1-one 2-chloro-8-hydroxymethylene-6,7,8,9-tetrahydropyrido[1,2-a]benzimidazol-9-one ethyl 7-nitro-1H-imidazo<1,2-a>pyrazolo<3,4-c>pyridine-8-carboxylate 1-oxopyrido(1',2':1,2)imidazo[5,4-d]-1,2,3-triazine 3-methyl-2-[5-(amino)pentan-1-ylthio]-1,4,7b-triazacyclopent[cd]indene 1-methyl-3-pentyldipyrido[1,2-a:3',4'-d]imidazole 3-cyclopropyl-1-methyldipyrido[1,2-a:3',4'-d]imidazole 8-oxo-2,7,9-trimethylimidazo<4.5-c>imidazo<1.2-a>pyridine 1,3,7b-triazacyclopentinden-4(3H)-one 2-(2'-adamantyl)-8-oxo-7,9-dimethylimidazo<4.5-c>imidazo<1.2-a>pyridine ((7R,8S)-3-(1,3,4-oxadiazol-2-yl)-7-(2,4,5-trifluorophenyl)-6,7,8,9-tetrahydrobenzo[4,5]imidazo[1,2-a]pyridin-8-yl)carbamate (7R,8S)-3-(1,2,4-oxadiazol-5-yl)-7-(2,4,5-trifluorophenyl)-6,7,8,9-tetrahydrobenzo[4,5]imidazo[1,2-a]pyridin-8-amine tert-butyl ((7R,8S)-3-(1H-tetrazol-5-yl)-7-(2,4,5-trifluorophenyl)-6,7,8,9-tetrahydrobenzo[4,5]imidazo[1,2-a]pyridin-8-yl)carbamate tert-butyl ((7R,8S)-3-(4-methyl-5-oxo-4,5-dihydro-1,3,4-oxadiazol-2-yl)-7-(2,4,5-trifluorophenyl)-6,7,8,9-tetrahydrobenzo[4,5]imidazo[1,2-a]pyridin-8-yl)carbamate tert-butyl ((7R,8S)-3-(2-methyl-2H-tetrazol-5-yl)-7-(2,4,5-trifluorophenyl)-6,7,8,9-tetrahydrobenzo[4,5]imidazo[1,2-a]pyridin-8-yl)carbamate (7R,8S)-3-(2-methyl-2H-tetrazol-5-yl)-7-(2,4,5-trifluorophenyl)-6,7,8,9-tetrahydrobenzo[4,5]imidazo[1,2-a]pyridin-8-amine 5-((7R,8S)-8-amino-7-(2,4,5-trifluorophenyl)-6,7,8,9-tetrahydrobenzo[4,5]imidazo[1,2-a]pyridin-3-yl)-3-methyl-1,3,4-oxadiazol-2(3H)-one tert-butyl ((7R,8S)-3-(4-methyl-5-oxo-4,5-dihydro-1,2,4-oxadiazol-3-yl)-7-(2,4,5-trifluorophenyl)-6,7,8,9-tetrahydrobenzo[4,5]imidazo[1,2-a]pyridin-8-yl)carbamate tert-butyl ((7R,8S)-3-(5-oxo-4,5-dihydro-1,2,4-oxadiazol-3-yl)-7-(2,4,5-trifluorophenyl)-6,7,8,9-tetrahydrobenzo[4,5]imidazo[1,2-a]pyridin-8-yl)carbamate 5-((7R,8S)-8-amino-7-(2,4,5-trifluorophenyl)-6,7,8,9-tetrahydrobenzo[4,5]imidazo[1,2-a]pyridin-3-yl)-1,2,4-oxadiazol-5(4H)-one tert-butyl ((7R,8S)-3-((Z)-carbamohydrazonoyl)-7-(2,4,5-trifluorophenyl)-6,7,8,9-tetrahydrobenzo[4,5]imidazo[1,2-a]pyridin-8-yl)carbamate (7R,8S)-8-amino-7-(2,4,5-trifluorophenyl)-6,7,8,9-tetrahydrobenzo[4,5]imidazo[1,2-a]pyridine-4-carbonitrile (7R,8S)-3-(1,2,4-oxadiazol-3-yl)-7-(2,4,5-trifluorophenyl)-6,7,8,9-tetrahydrobenzo[4,5]imidazo[1,2-a]pyridin-8-amine 3-((7R,8S)-8-amino-7-(2,4,5-trifluorophenyl)-6,7,8,9-tetrahydrobenzo[4,5]imidazo[1,2-a]pyridin-3-yl)-4-methyl-1,2,4-oxadiazol-5(4H)-one ((7R,8S)-3-(1H-tetrazol-5-yl)-7-(2,4,5-trifluorophenyl)-6,7,8,9-tetrahydrobenzo[4,5]imidazo[1,2-a]pyridin-8-yl)carbamate (7R,8S)-3-(5-methyl-1,2,4-oxadiazol-3-yl)-7-(2,4,5-trifluorophenyl)-6,7,8,9-tetrahydrobenzo[4,5]imidazo[1,2-a]pyridin-8-amine tert-butyl ((7R,8S)-3-(5-oxo-4,5-dihydro-1,3,4-oxadiazol-2-yl)-7-(2,4,5-trifluorophenyl)-6,7,8,9-tetrahydrobenzo[4,5]imidazo[1,2-a]pyridin-8-yl)carbamate tert-butyl ((7R,8S)-3-cyano-7-(2,4,5-trifluorophenyl)-6,7,8,9-tetrahydrobenzo[4,5]imidazo[1,2-a]pyridin-8-yl)carbamate (7R,8S)-3-(1,3,4-oxadiazol-2-yl)-7-(2,4,5-trifluorophenyl)-6,7,8,9-tetrahydrobenzo[4,5]imidazo[1,2-a]pyridin-8-amine

    热门分子