3-Methylbutyl(5-methylhexyl)phosphane

• 分子结构分类: 有机化合物 - 有机磷化合物
• 英文名称: 3-Methylbutyl(5-methylhexyl)phosphane
• 英文别名: 3-methylbutyl(5-methylhexyl)phosphane
• 化学式: C₁₂H₂₇P
• 分子量: 202.32
• InChiKey: RGTKNTBMJKTZKN-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.2
• 重原子数：
  13
• 可旋转键数：
  8
• 环数：
  0.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  0
• 氢给体数：
  0
• 氢受体数：
  0

文献信息

• MARKERS FOR EARLY DIAGNOSIS OF OVARIAN CANCER, MONITORING DURING THERAPY, AND NEW THERAPY OPTIONS DURING AND AFTER CHEMOTHERAPY
  申请人：The Board of Trustees of the University of Arkansas

  公开号：US20140193426A1

  公开（公告）日：2014-07-10

  The inventors have identified several proteases and a protease inhibitor that are overexpressed in ovarian cancer tumors. They have developed monoclonal antibodies against the proteins and shown that they can be detected in serum and the levels of the proteins in serum fluctuate during cancer treatment. They have shown that serum assays for the proteases and protease inhibitor can be used for early detection of ovarian cancer, and for monitoring cancer treatment.