N-(1-methylsulfanylethyl)propan-2-amine

• 分子结构分类: 有机化合物 - 有机硫化合物 - 硫半缩醛胺衍生物
• 英文名称: N-(1-methylsulfanylethyl)propan-2-amine
• 化学式: C₆H₁₅NS
• 分子量: 133.26
• InChiKey: IBGNNUMJQVJEOP-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.8
• 重原子数：
  8
• 可旋转键数：
  3
• 环数：
  0.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  37.3
• 氢给体数：
  1
• 氢受体数：
  2

文献信息

• INHIBITION OF OLIG2 ACTIVITY
  申请人：Curtana Pharmaceuticals, Inc.

  公开号：US20210253535A1

  公开（公告）日：2021-08-19

  Described herein are compounds and pharmaceutical compositions containing such compounds, which inhibit the activity of Olig2. Also described herein are methods of using such Olig2 inhibitors, alone and in combination with other compounds, for treating cancer and other diseases. In particular the Olig2 inhibitors may be used to treat glioblastoma.