2-hydroxymethyl-2-phenyl-butyric acid tropan-3-yl ester | 69946-28-7

• 分子结构分类: 有机化合物 - 生物碱及其衍生物 - 托烷生物碱
• 英文名称: 2-hydroxymethyl-2-phenyl-butyric acid tropan-3-yl ester
• 英文别名: 8-Methyl-8-azabicyclo[3.2.1]oct-3-yl 2-(hydroxymethyl)-2-phenylbutanoate；(8-methyl-8-azabicyclo[3.2.1]octan-3-yl) 2-(hydroxymethyl)-2-phenylbutanoate
• CAS: 69946-28-7
• 化学式: C₁₉H₂₇NO₃
• mdl: MFCD01241124
• 分子量: 317.428
• InChiKey: UVFFMBYRGIAWRW-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3
• 重原子数：
  23
• 可旋转键数：
  6
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.63
• 拓扑面积：
  49.8
• 氢给体数：
  1
• 氢受体数：
  4

文献信息

• AZABICYCLO AND DIAZEPINE DERIVATIVES
  申请人：Alcon Inc.

  公开号：US20210179616A1

  公开（公告）日：2021-06-17

  The present invention provides in one aspect azabicyclo and diazepine derivatives useful as modulators of muscarinic receptors. In another aspect, the present invention provides pharmaceutical compositions for treating ocular diseases, the compositions comprising at least one muscarinic receptor modulator.