8,8-Dimethyl-8-azoniabicyclo[3.2.1]octane

• 分子结构分类: 有机化合物 - 生物碱及其衍生物 - 托烷生物碱
• 英文名称: 8,8-Dimethyl-8-azoniabicyclo[3.2.1]octane
• 化学式: C9H18N+
• 分子量: 140.25
• InChiKey: HNEPOZDQJSDXTK-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.7
• 重原子数：
  10
• 可旋转键数：
  0
• 环数：
  2.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  0
• 氢给体数：
  0
• 氢受体数：
  0

文献信息

• [EN] BOLAAMPHIPHILIC COMPOUNDS, COMPOSITIONS AND USES THEREOF<br/>[FR] COMPOSITIONS, COMPOSÉS BOLAAMPHIPHILES, ET LEURS UTILISATIONS
  申请人：LAUREN SCIENCES LLC

  公开号：WO2016168580A1

  公开（公告）日：2016-10-20

  Bolaamphiphilic compounds are provided according to formula (I); where HG1, HG2 and L1 are as defined herein. Provided bolaamphiphilic compounds and the pharmaceutical compositions thereof are useful for delivering GDNF or NGF into animal or human brain.

  根据公式（I），提供了双亲嵌段化合物；其中HG1、HG2和L1如本文所定义。提供的双亲嵌段化合物及其制成的药物组合物可用于将GDNF或NGF输送到动物或人类大脑中。
• [EN] BOLAAMPHIPHILIC COMPOUNDS, COMPOSITIONS AND USES THEREOF<br/>[FR] COMPOSÉS BOLAAMPHIPHILES, COMPOSITIONS ET LEURS UTILISATIONS
  申请人：LAUREN SCIENCES LLC

  公开号：WO2014039501A1

  公开（公告）日：2014-03-13

  Bolaamphiphilic compounds are provided according to formula (I): where HG1, HG2 and L1 are as defined herein. Provided bolaamphilphilic compounds and the pharmaceutical compositions thereof are useful for delivering GDNF or NGF into animal or human brain.

  提供根据以下公式（I）提供的双亲嵌段化合物：其中HG1、HG2和L1如本文所定义。提供的双亲嵌段化合物及其药物组合物对将GDNF或NGF输送到动物或人类大脑中是有用的。
• BOLAAMPHIPHILIC COMPOUNDS, COMPOSITIONS AND USES THEREOF
  申请人：Lauren Sciences LLC

  公开号：US20150110875A1

  公开（公告）日：2015-04-23

  Bolaamphiphilic compounds are provided according to formula I: HG 2 -L 1 -HG 1 I where HG 1 , HG 2 and L 1 are as defined herein. Provided bolaamphilphilic compounds and the pharmaceutical compositions thereof are useful for delivering GDNF or NGF into animal or human brain.

  提供了按照公式I定义的Bolaamphiphilic化合物：HG2-L1-HG1，其中HG1、HG2和L1如此定义。提供的Bolaamphilphilic化合物及其制药组合物对于将GDNF或NGF输送到动物或人类大脑中是有用的。
• AZABICYCLIC AMIDES OR ESTERS OF HALOGENATED BENZOIC ACIDS
  申请人：BEECHAM GROUP PLC

  公开号：EP0563087A1

  公开（公告）日：1993-10-06
• High silica DDR-type molecular sieve, its synthesis and use
  申请人：Cao Guang

  公开号：US20090111959A1

  公开（公告）日：2009-04-30

  A crystalline material has a DDR framework type and, in its calcined, anhydrous form, has a composition involving the molar relationship: ( n )X 2 O 3 :YO 2 , wherein X is a trivalent element, Y is a tetravalent element and n is from 0 to less than 0.01 and wherein the crystals of said material have an average diameter less than or equal to 2 microns. The material is synthesized in the presence of an N-ethyltropanium compound as directing agent.