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    首页 分子通 按分子结构分类 有机化合物 有机杂环化合物 二氮杂萘

    二氮杂萘

    相关化合物

    中文名称 英文名称 CAS号 化学式 结构式图片
    —— (2S,10R)-13-[2-(6,7-dimethoxy-4-methyl-3-oxoquinoxalin-2-yl)ethyl]-2-(4-hydroxy-3,5-dimethoxyphenyl)-5-methyl-11,13,15-triazatetracyclo[8.7.0.03,8.011,15]heptadeca-1(17),3(8),5-triene-4,7,12,14-tetrone —— C36H35N5O10
    (2S,10R)-13-[2-(6,7-dimethoxy-4-methyl-3-oxoquinoxalin-2-yl)ethyl]-2-(4-hydroxy-3,5-dimethoxyphenyl)-5-methyl-11,13,15-triazatetracyclo[8.7.0.03,8.011,15]heptadeca-1(17),3(8),5-triene-4,7,12,14-tetrone
    —— (2S,3S,8R,10R)-13-[2-(6,7-dimethoxy-4-methyl-3-oxoquinoxalin-2-yl)ethyl]-2-[2-(4-hydroxy-3-methoxyphenyl)ethenyl]-3,5-dimethyl-11,13,15-triazatetracyclo[8.7.0.03,8.011,15]heptadeca-1(17),5-diene-4,7,12,14-tetrone —— C38H39N5O9
    (2S,3S,8R,10R)-13-[2-(6,7-dimethoxy-4-methyl-3-oxoquinoxalin-2-yl)ethyl]-2-[2-(4-hydroxy-3-methoxyphenyl)ethenyl]-3,5-dimethyl-11,13,15-triazatetracyclo[8.7.0.03,8.011,15]heptadeca-1(17),5-diene-4,7,12,14-tetrone
    —— (2R,10R)-6-bromo-13-[2-(6,7-dimethoxy-4-methyl-3-oxoquinoxalin-2-yl)ethyl]-2-(2-hydroxy-5-methoxyphenyl)-11,13,15-triazatetracyclo[8.7.0.03,8.011,15]heptadeca-1(17),3(8),5-triene-4,7,12,14-tetrone —— C34H30BrN5O9
    (2R,10R)-6-bromo-13-[2-(6,7-dimethoxy-4-methyl-3-oxoquinoxalin-2-yl)ethyl]-2-(2-hydroxy-5-methoxyphenyl)-11,13,15-triazatetracyclo[8.7.0.03,8.011,15]heptadeca-1(17),3(8),5-triene-4,7,12,14-tetrone
    —— (2R,10R)-13-[2-(6,7-dimethoxy-4-methyl-3-oxoquinoxalin-2-yl)ethyl]-2-(2-hydroxy-3-methoxyphenyl)-5-methyl-11,13,15-triazatetracyclo[8.7.0.03,8.011,15]heptadeca-1(17),3(8),5-triene-4,7,12,14-tetrone —— C35H33N5O9
    (2R,10R)-13-[2-(6,7-dimethoxy-4-methyl-3-oxoquinoxalin-2-yl)ethyl]-2-(2-hydroxy-3-methoxyphenyl)-5-methyl-11,13,15-triazatetracyclo[8.7.0.03,8.011,15]heptadeca-1(17),3(8),5-triene-4,7,12,14-tetrone
    —— (2R,10R)-13-[2-(6,7-dimethoxy-4-methyl-3-oxoquinoxalin-2-yl)ethyl]-2-(6-hydroxy-4H-chromen-3-yl)-6-methyl-11,13,15-triazatetracyclo[8.7.0.03,8.011,15]heptadeca-1(17),3(8),5-triene-4,7,12,14-tetrone —— C37H33N5O9
    (2R,10R)-13-[2-(6,7-dimethoxy-4-methyl-3-oxoquinoxalin-2-yl)ethyl]-2-(6-hydroxy-4H-chromen-3-yl)-6-methyl-11,13,15-triazatetracyclo[8.7.0.03,8.011,15]heptadeca-1(17),3(8),5-triene-4,7,12,14-tetrone
    —— (2R,10R)-13-[2-(6,7-dimethoxy-4-methyl-3-oxoquinoxalin-2-yl)ethyl]-2-(2-hydroxy-5-methoxyphenyl)-6-methyl-11,13,15-triazatetracyclo[8.7.0.03,8.011,15]heptadeca-1(17),3(8),5-triene-4,7,12,14-tetrone —— C35H33N5O9
    (2R,10R)-13-[2-(6,7-dimethoxy-4-methyl-3-oxoquinoxalin-2-yl)ethyl]-2-(2-hydroxy-5-methoxyphenyl)-6-methyl-11,13,15-triazatetracyclo[8.7.0.03,8.011,15]heptadeca-1(17),3(8),5-triene-4,7,12,14-tetrone
    —— (2S)-2-(7-chloro-4-oxo-3H-quinazolin-2-yl)-3-oxo-5-prop-2-ynoxypentanenitrile —— C16H12ClN3O3
    (2S)-2-(7-chloro-4-oxo-3H-quinazolin-2-yl)-3-oxo-5-prop-2-ynoxypentanenitrile
    —— (2R,10R)-13-[2-(6,7-dimethoxy-4-methyl-3-oxoquinoxalin-2-yl)ethyl]-2-[2-(2-hydroxyethoxy)phenyl]-5-methyl-11,13,15-triazatetracyclo[8.7.0.03,8.011,15]heptadeca-1(17),3(8),5-triene-4,7,12,14-tetrone —— C36H35N5O9
    (2R,10R)-13-[2-(6,7-dimethoxy-4-methyl-3-oxoquinoxalin-2-yl)ethyl]-2-[2-(2-hydroxyethoxy)phenyl]-5-methyl-11,13,15-triazatetracyclo[8.7.0.03,8.011,15]heptadeca-1(17),3(8),5-triene-4,7,12,14-tetrone
    —— (2S,10R)-13-[2-(6,7-dimethoxy-4-methyl-3-oxoquinoxalin-2-yl)ethyl]-2-(3-fluoro-4-hydroxyphenyl)-5-methyl-11,13,15-triazatetracyclo[8.7.0.03,8.011,15]heptadeca-1(17),3(8),5-triene-4,7,12,14-tetrone —— C34H30FN5O8
    (2S,10R)-13-[2-(6,7-dimethoxy-4-methyl-3-oxoquinoxalin-2-yl)ethyl]-2-(3-fluoro-4-hydroxyphenyl)-5-methyl-11,13,15-triazatetracyclo[8.7.0.03,8.011,15]heptadeca-1(17),3(8),5-triene-4,7,12,14-tetrone
    —— (2S,3S,8R,10R)-13-[2-(6,7-dimethoxy-4-methyl-3-oxoquinoxalin-2-yl)ethyl]-2-[4-(2-hydroxyethoxy)phenyl]-3,5,6,8-tetramethyl-11,13,15-triazatetracyclo[8.7.0.03,8.011,15]heptadeca-1(17),5-diene-4,7,12,14-tetrone —— C39H43N5O9
    (2S,3S,8R,10R)-13-[2-(6,7-dimethoxy-4-methyl-3-oxoquinoxalin-2-yl)ethyl]-2-[4-(2-hydroxyethoxy)phenyl]-3,5,6,8-tetramethyl-11,13,15-triazatetracyclo[8.7.0.03,8.011,15]heptadeca-1(17),5-diene-4,7,12,14-tetrone
    —— (1R,10S,11S,15R)-13-[5-(5-chloro-3-methyl-1-benzothiophen-2-yl)-2-methylpyrazol-3-yl]-4-[2-(6,7-dimethoxy-4-methyl-3-oxoquinoxalin-2-yl)ethyl]-10-[4-(2-hydroxyethoxy)phenyl]-11-methyl-2,4,6,13-tetrazatetracyclo[7.7.0.02,6.011,15]hexadec-8-ene-3,5,12,14-tetrone —— C47H45ClN8O9S
    (1R,10S,11S,15R)-13-[5-(5-chloro-3-methyl-1-benzothiophen-2-yl)-2-methylpyrazol-3-yl]-4-[2-(6,7-dimethoxy-4-methyl-3-oxoquinoxalin-2-yl)ethyl]-10-[4-(2-hydroxyethoxy)phenyl]-11-methyl-2,4,6,13-tetrazatetracyclo[7.7.0.02,6.011,15]hexadec-8-ene-3,5,12,14-tetrone
    —— (1R,10R,11S,15R)-13-[5-(5-chloro-3-methyl-1-benzothiophen-2-yl)-2-methylpyrazol-3-yl]-4-[2-(6,7-dimethoxy-4-methyl-3-oxoquinoxalin-2-yl)ethyl]-10-(6-hydroxy-4H-chromen-3-yl)-11-methyl-2,4,6,13-tetrazatetracyclo[7.7.0.02,6.011,15]hexadec-8-ene-3,5,12,14-tetrone —— C48H43ClN8O9S
    (1R,10R,11S,15R)-13-[5-(5-chloro-3-methyl-1-benzothiophen-2-yl)-2-methylpyrazol-3-yl]-4-[2-(6,7-dimethoxy-4-methyl-3-oxoquinoxalin-2-yl)ethyl]-10-(6-hydroxy-4H-chromen-3-yl)-11-methyl-2,4,6,13-tetrazatetracyclo[7.7.0.02,6.011,15]hexadec-8-ene-3,5,12,14-tetrone
    —— (1S,10R)-4,13-bis[2-(6,7-dimethoxy-4-methyl-3-oxoquinoxalin-2-yl)ethyl]-10-[2-(2-hydroxyethoxy)phenyl]-2,4,6,11,13,15-hexazatetracyclo[7.7.0.02,6.011,15]hexadec-8-ene-3,5,12,14-tetrone —— C44H46N10O12
    (1S,10R)-4,13-bis[2-(6,7-dimethoxy-4-methyl-3-oxoquinoxalin-2-yl)ethyl]-10-[2-(2-hydroxyethoxy)phenyl]-2,4,6,11,13,15-hexazatetracyclo[7.7.0.02,6.011,15]hexadec-8-ene-3,5,12,14-tetrone
    —— (1S,10R)-4,13-bis[2-(6,7-dimethoxy-4-methyl-3-oxoquinoxalin-2-yl)ethyl]-10-[2-hydroxy-5-(trifluoromethoxy)phenyl]-2,4,6,11,13,15-hexazatetracyclo[7.7.0.02,6.011,15]hexadec-8-ene-3,5,12,14-tetrone —— C43H41F3N10O12
    (1S,10R)-4,13-bis[2-(6,7-dimethoxy-4-methyl-3-oxoquinoxalin-2-yl)ethyl]-10-[2-hydroxy-5-(trifluoromethoxy)phenyl]-2,4,6,11,13,15-hexazatetracyclo[7.7.0.02,6.011,15]hexadec-8-ene-3,5,12,14-tetrone
    —— (1S,10S)-4,13-bis[2-(6,7-dimethoxy-4-methyl-3-oxoquinoxalin-2-yl)ethyl]-10-[2-(4-hydroxy-3,5-dimethoxyphenyl)ethenyl]-2,4,6,11,13,15-hexazatetracyclo[7.7.0.02,6.011,15]hexadec-8-ene-3,5,12,14-tetrone —— C46H48N10O13
    (1S,10S)-4,13-bis[2-(6,7-dimethoxy-4-methyl-3-oxoquinoxalin-2-yl)ethyl]-10-[2-(4-hydroxy-3,5-dimethoxyphenyl)ethenyl]-2,4,6,11,13,15-hexazatetracyclo[7.7.0.02,6.011,15]hexadec-8-ene-3,5,12,14-tetrone
    —— (1S,10S)-10-(3-chloro-4-hydroxy-5-methoxyphenyl)-4,13-bis[2-(6,7-dimethoxy-4-methyl-3-oxoquinoxalin-2-yl)ethyl]-2,4,6,11,13,15-hexazatetracyclo[7.7.0.02,6.011,15]hexadec-8-ene-3,5,12,14-tetrone —— C43H43ClN10O12
    (1S,10S)-10-(3-chloro-4-hydroxy-5-methoxyphenyl)-4,13-bis[2-(6,7-dimethoxy-4-methyl-3-oxoquinoxalin-2-yl)ethyl]-2,4,6,11,13,15-hexazatetracyclo[7.7.0.02,6.011,15]hexadec-8-ene-3,5,12,14-tetrone
    —— (1S,10R)-4,13-bis[2-(6,7-dimethoxy-4-methyl-3-oxoquinoxalin-2-yl)ethyl]-10-(4-hydroxy-2-methoxyphenyl)-2,4,6,11,13,15-hexazatetracyclo[7.7.0.02,6.011,15]hexadec-8-ene-3,5,12,14-tetrone —— C43H44N10O12
    (1S,10R)-4,13-bis[2-(6,7-dimethoxy-4-methyl-3-oxoquinoxalin-2-yl)ethyl]-10-(4-hydroxy-2-methoxyphenyl)-2,4,6,11,13,15-hexazatetracyclo[7.7.0.02,6.011,15]hexadec-8-ene-3,5,12,14-tetrone
    —— (1S,10R)-4,13-bis[2-(6,7-dimethoxy-4-methyl-3-oxoquinoxalin-2-yl)ethyl]-10-(2-hydroxy-4,6-dimethoxyphenyl)-2,4,6,11,13,15-hexazatetracyclo[7.7.0.02,6.011,15]hexadec-8-ene-3,5,12,14-tetrone —— C44H46N10O13
    (1S,10R)-4,13-bis[2-(6,7-dimethoxy-4-methyl-3-oxoquinoxalin-2-yl)ethyl]-10-(2-hydroxy-4,6-dimethoxyphenyl)-2,4,6,11,13,15-hexazatetracyclo[7.7.0.02,6.011,15]hexadec-8-ene-3,5,12,14-tetrone
    —— (3S,4R)-4-[4-[(1R)-1-[4-(2,3-diethyl-7,8-dihydro-5H-1,6-naphthyridin-6-yl)butan-2-ylideneamino]oxyethyl]triazol-1-yl]oxolan-3-ol —— C24H36N6O3
    (3S,4R)-4-[4-[(1R)-1-[4-(2,3-diethyl-7,8-dihydro-5H-1,6-naphthyridin-6-yl)butan-2-ylideneamino]oxyethyl]triazol-1-yl]oxolan-3-ol
    —— (6R)-6-phenyl-5,6,7,8-tetrahydro-1H-quinazoline-2,4-dione —— C14H14N2O2
    (6R)-6-phenyl-5,6,7,8-tetrahydro-1H-quinazoline-2,4-dione
    —— (6S)-6-phenyl-5,6,7,8-tetrahydro-1H-quinazoline-2,4-dione —— C14H14N2O2
    (6S)-6-phenyl-5,6,7,8-tetrahydro-1H-quinazoline-2,4-dione
    —— (2E)-2-[(2E)-2-(3-bromo-6-oxocyclohexa-2,4-dien-1-ylidene)ethylidene]-3-(3-hydroxyphenyl)-1H-quinazolin-4-one —— C22H15BrN2O3
    (2E)-2-[(2E)-2-(3-bromo-6-oxocyclohexa-2,4-dien-1-ylidene)ethylidene]-3-(3-hydroxyphenyl)-1H-quinazolin-4-one
    —— 1,4-dimethyl-N-[(4-methylphenyl)methyl]-2,3-dioxoquinoxaline-6-carboxamide —— C19H19N3O3
    1,4-dimethyl-N-[(4-methylphenyl)methyl]-2,3-dioxoquinoxaline-6-carboxamide
    —— 6-Methyl-7-[(4-methylpiperidin-1-yl)sulfonyl]-1,2,3,4-tetrahydroquinoxaline-2,3-dione —— C15H19N3O4S
    6-Methyl-7-[(4-methylpiperidin-1-yl)sulfonyl]-1,2,3,4-tetrahydroquinoxaline-2,3-dione
    —— N~6~-benzyl-7-methyl-2,3-dioxo-1,2,3,4-tetrahydro-6-quinoxalinesulfonamide —— C16H15N3O4S
    N~6~-benzyl-7-methyl-2,3-dioxo-1,2,3,4-tetrahydro-6-quinoxalinesulfonamide
    —— N-cyclopentyl-7-methyl-2,3-dioxo-1,4-dihydroquinoxaline-6-sulfonamide —— C14H17N3O4S
    N-cyclopentyl-7-methyl-2,3-dioxo-1,4-dihydroquinoxaline-6-sulfonamide
    —— 1-[(2R)-2-cyclohexyl-1-hydroxypropan-2-yl]-3-[(5R)-2-methyl-5,6,7,8-tetrahydroquinazolin-5-yl]urea —— C19H30N4O2
    1-[(2R)-2-cyclohexyl-1-hydroxypropan-2-yl]-3-[(5R)-2-methyl-5,6,7,8-tetrahydroquinazolin-5-yl]urea
    —— 1-[2-(cyclopropylmethoxy)ethyl]-1-methyl-3-[(5S)-2-methyl-5,6,7,8-tetrahydroquinazolin-5-yl]urea —— C17H26N4O2
    1-[2-(cyclopropylmethoxy)ethyl]-1-methyl-3-[(5S)-2-methyl-5,6,7,8-tetrahydroquinazolin-5-yl]urea
    —— 1-[(2R)-2-cyclohexyl-1-hydroxypropan-2-yl]-3-[(5S)-2-methyl-5,6,7,8-tetrahydroquinazolin-5-yl]urea —— C19H30N4O2
    1-[(2R)-2-cyclohexyl-1-hydroxypropan-2-yl]-3-[(5S)-2-methyl-5,6,7,8-tetrahydroquinazolin-5-yl]urea
    —— 1-[2-(cyclopropylmethoxy)ethyl]-1-methyl-3-[(5R)-2-methyl-5,6,7,8-tetrahydroquinazolin-5-yl]urea —— C17H26N4O2
    1-[2-(cyclopropylmethoxy)ethyl]-1-methyl-3-[(5R)-2-methyl-5,6,7,8-tetrahydroquinazolin-5-yl]urea
    —— 1-[(2S)-2-cyclohexyl-1-hydroxypropan-2-yl]-3-[(5R)-2-methyl-5,6,7,8-tetrahydroquinazolin-5-yl]urea —— C19H30N4O2
    1-[(2S)-2-cyclohexyl-1-hydroxypropan-2-yl]-3-[(5R)-2-methyl-5,6,7,8-tetrahydroquinazolin-5-yl]urea
    —— 2-Methyl-5-oxo-[1,3,4]thiadiazolo[2,3-b]quinazoline-8-carboxylic acid —— C11H7N3O3S
    2-Methyl-5-oxo-[1,3,4]thiadiazolo[2,3-b]quinazoline-8-carboxylic acid
    —— 3-amino-4-oxo-2-sulfanylidene-1H-quinazoline-7-carboxylic acid —— C9H7N3O3S
    3-amino-4-oxo-2-sulfanylidene-1H-quinazoline-7-carboxylic acid
    —— 5-Oxo-N3,N8-bis(propan-2-YL)-1-sulfanylidene-1H,4H,5H-[1,3]thiazolo[3,4-A]quinazoline-3,8-dicarboxamide —— C18H20N4O3S2
    5-Oxo-N3,N8-bis(propan-2-YL)-1-sulfanylidene-1H,4H,5H-[1,3]thiazolo[3,4-A]quinazoline-3,8-dicarboxamide
    —— 2-(4-oxopyrrolo[1,2-a]quinoxalin-5-yl)-N-(1,2,3,4-tetrahydronaphthalen-1-yl)acetamide —— C23H21N3O2
    2-(4-oxopyrrolo[1,2-a]quinoxalin-5-yl)-N-(1,2,3,4-tetrahydronaphthalen-1-yl)acetamide
    —— 4-{4-Oxo-4H,5H-pyrrolo[1,2-A]quinoxalin-5-YL}-N-(1-phenylethyl)butanamide —— C23H23N3O2
    4-{4-Oxo-4H,5H-pyrrolo[1,2-A]quinoxalin-5-YL}-N-(1-phenylethyl)butanamide
    —— Ethyl 4-({8-chloro-[1,2,4]triazolo[4,3-A]quinoxalin-4-YL}amino)piperidine-1-carboxylate —— C17H19ClN6O2
    Ethyl 4-({8-chloro-[1,2,4]triazolo[4,3-A]quinoxalin-4-YL}amino)piperidine-1-carboxylate
    —— N-(2-Ethylphenyl)-3-{4-oxo-4H,5H-pyrrolo[1,2-A]quinoxalin-5-YL}propanamide —— C22H21N3O2
    N-(2-Ethylphenyl)-3-{4-oxo-4H,5H-pyrrolo[1,2-A]quinoxalin-5-YL}propanamide
    —— 4-{4-Oxo-4H,5H-pyrrolo[1,2-A]quinoxalin-5-YL}-N-(1,2,3,4-tetrahydronaphthalen-1-YL)butanamide —— C25H25N3O2
    4-{4-Oxo-4H,5H-pyrrolo[1,2-A]quinoxalin-5-YL}-N-(1,2,3,4-tetrahydronaphthalen-1-YL)butanamide
    —— Methyl 3-(4-oxopyrrolo[1,2-a]quinoxalin-5-yl)propanoate —— C15H14N2O3
    Methyl 3-(4-oxopyrrolo[1,2-a]quinoxalin-5-yl)propanoate
    —— 1-[(2S)-2-cyclohexyl-1-hydroxypropan-2-yl]-3-[(5S)-2-methyl-5,6,7,8-tetrahydroquinazolin-5-yl]urea —— C19H30N4O2
    1-[(2S)-2-cyclohexyl-1-hydroxypropan-2-yl]-3-[(5S)-2-methyl-5,6,7,8-tetrahydroquinazolin-5-yl]urea
    —— 1,4-dimethyl-2,3-dioxo-N-propylquinoxaline-6-sulfonamide —— C13H17N3O4S
    1,4-dimethyl-2,3-dioxo-N-propylquinoxaline-6-sulfonamide
    —— 2-(3,5-Dimethylpiperidin-1-yl)-8-methylpyridazino[6,1-b]quinazolin-10-one —— C19H22N4O
    2-(3,5-Dimethylpiperidin-1-yl)-8-methylpyridazino[6,1-b]quinazolin-10-one
    —— N,1,4-trimethyl-N-(3-methylphenyl)-2,3-dioxo-1,2,3,4-tetrahydroquinoxaline-6-sulfonamide —— C18H19N3O4S
    N,1,4-trimethyl-N-(3-methylphenyl)-2,3-dioxo-1,2,3,4-tetrahydroquinoxaline-6-sulfonamide
    —— N-phenyl-2-(3-pyrrolidin-1-ylquinoxalin-2-yl)sulfanylacetamide —— C20H20N4OS
    N-phenyl-2-(3-pyrrolidin-1-ylquinoxalin-2-yl)sulfanylacetamide
    —— N-[(2-Chlorophenyl)methyl]-4-{1-[(2,5-dimethylphenyl)methyl]-2,4-dioxo-1,2,3,4-tetrahydroquinazolin-3-YL}butanamide —— C28H28ClN3O3
    N-[(2-Chlorophenyl)methyl]-4-{1-[(2,5-dimethylphenyl)methyl]-2,4-dioxo-1,2,3,4-tetrahydroquinazolin-3-YL}butanamide
    —— 2-({8,9-Dimethoxy-2-methyl-[1,2,4]triazolo[1,5-C]quinazolin-5-YL}sulfanyl)-N-[2-(3,4-dimethoxyphenyl)ethyl]acetamide —— C24H27N5O5S
    2-({8,9-Dimethoxy-2-methyl-[1,2,4]triazolo[1,5-C]quinazolin-5-YL}sulfanyl)-N-[2-(3,4-dimethoxyphenyl)ethyl]acetamide
    —— 2-{3-[2-(3,4-Dimethoxyphenyl)ethyl]-2,4-dioxo-1,2,3,4-tetrahydroquinazolin-1-YL}-N-methyl-N-phenylacetamide —— C27H27N3O5
    2-{3-[2-(3,4-Dimethoxyphenyl)ethyl]-2,4-dioxo-1,2,3,4-tetrahydroquinazolin-1-YL}-N-methyl-N-phenylacetamide
    —— 4-(7-chloro-2,4-dioxo-1H-quinazolin-3-yl)-N-(2,3-dimethylcyclohexyl)butanamide —— C20H26ClN3O3
    4-(7-chloro-2,4-dioxo-1H-quinazolin-3-yl)-N-(2,3-dimethylcyclohexyl)butanamide
    —— N-cycloheptyl-3-{4-[(4-fluorophenyl)methyl]-5-oxo-4H,5H-[1,2,4]triazolo[4,3-a]quinazolin-1-yl}propanamide —— C26H28FN5O2
    N-cycloheptyl-3-{4-[(4-fluorophenyl)methyl]-5-oxo-4H,5H-[1,2,4]triazolo[4,3-a]quinazolin-1-yl}propanamide