2,4,5-Trimethyl-4,5-dihydro-1H-imidazole | 61764-87-2

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 亚胺内酰胺
• 英文名称: 2,4,5-Trimethyl-4,5-dihydro-1H-imidazole
• CAS: 61764-87-2
• 化学式: C₆H₁₂N₂
• 分子量: 112.17
• InChiKey: VBAQHRRODCXYPB-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.1
• 重原子数：
  8
• 可旋转键数：
  0
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.83
• 拓扑面积：
  24.4
• 氢给体数：
  1
• 氢受体数：
  1

反应信息

• 作为产物：
  描述：

  丁二炔 、 meso-2,3-diaminobutane 生成 2,4,5-Trimethyl-4,5-dihydro-1H-imidazole
  参考文献：
  名称：

  SCHROTH W.; PREISS A.; BETHIN M.; BARTSCH W.-D., Z. CHEM. , 1977, 17, NO 6, 216-218

  摘要：

  DOI：

文献信息

• Modulators of melanocortin receptor
  申请人：Vos J. Tricia

  公开号：US20070293498A1

  公开（公告）日：2007-12-20

  This invention provides compounds and methods for treating melanocortin receptor associated disorders, such as weight loss disorders including cachexia resulting from cancer and other chronic illnesses. The compounds are represented by formula I: wherein X is oxygen or sulfur; G is G1 or G2: L 1 , L 2 , L 3 and Q are linker groups, and Rings A, B and C, and R 1 -R 14 are described in the specification. The compounds are antagonists of melanocortin receptors.

  本发明提供了化合物和方法，用于治疗黑色素皮质素受体相关疾病，如由癌症和其他慢性疾病引起的消瘦症等减重疾病。化合物由公式I表示：其中X是氧或硫；G是G1或G2：L1，L2，L3和Q是连接基，环A，B和C以及R1-R14在说明书中描述。化合物是黑色素皮质素受体的拮抗剂。
• Epoxy resin composition using latent curing agent and curable by photo and heat in combination
  申请人：Iwaya Kazuki

  公开号：US20090076180A1

  公开（公告）日：2009-03-19

  The present invention is to provide a latent curing type epoxy resin composition which comprises (A) 100 parts by weight of an epoxy resin, (B) 5 to 25 parts by weight of a cation polymerization photo initiator, and (C) 5 to 35 parts by weight of at least one heatset anion curing agent selected from the group consisting of an epoxy adduct with an amine compound, a urea adduct with an amine compound and a compound in which an isocyanate compound is added to a hydroxyl group of an epoxy adduct with an amine compound.
• COPOLYMER COMPOSED OF A POLYPHENYLENE AND A FLEXIBLE CHAIN COMPONENT
  申请人：Herz Hans-Georg

  公开号：US20120302704A1

  公开（公告）日：2012-11-29

  A copolymer is described which is prepared by reacting a polyphenylene having two terminal coupling groups X 1 and X 2 with a flexible chain component which has a flexible chain having two terminal coupling groups Y 1 and Y 2 . A high modulus of elasticity, high media resistance, and cost-effective, large-scale production may be achieved in that the flexible chain has a chain length of less than or equal to 95 chain atoms, and each of coupling groups X 1 and X 2 reacts with one of coupling groups Y 1 and Y 2 , forming a bond selected from the group composed of carboxylic acid amide, carboxylic acid ester, carboxylic acid imide, urethane, carbonate, urea, thiourea, sulfonic acid amide, sulfonic acid ester, imidazole, oxazole, thiazole, oxazoline, imidazoline, amine, ether, and thioether bonds.
• NICLOSAMIDE ANALOGUES AND THERAPEUTIC USE THEREOF
  申请人：Duke University

  公开号：US20210179615A1

  公开（公告）日：2021-06-17

  Described are niclosamide analogue compounds, pharmaceutical compositions thereof, and method of using the corner pounds and compositions for treating a disease associated with dysregulation of the Wnt/Frizzled signaling pathway, such as cancer, fatty liver, antibiotic resistance, and viral infection. The disclosed compounds and compositions may also be used for modulating mitochondrial function and for treating certain non-cancer diseases and/or diorders, such as diabetes, fibrotic disease, primary sclerosing cholangitis.
• US7365070B2
  申请人：——

  公开号：US7365070B2

  公开（公告）日：2008-04-29