[1,3,2]dioxaphospholan-2-yl-isopropyl-amine | 51439-09-9

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 二氧磷杂环戊烷
• 英文名称: [1,3,2]dioxaphospholan-2-yl-isopropyl-amine
• 英文别名: 2-(N-Isopropylamino)-1,3,2-dioxaphospholan；Isopropylamino-ethylendioxyphosphin；N-(Propan-2-yl)-1,3,2-dioxaphospholan-2-amine；N-propan-2-yl-1,3,2-dioxaphospholan-2-amine
• CAS: 51439-09-9
• 化学式: C₅H₁₂NO₂P
• 分子量: 149.13
• InChiKey: HOOFLQWZBKQFHI-UHFFFAOYSA-N

物化性质

• 沸点：
  151.4±23.0 °C(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  0.4
• 重原子数：
  9
• 可旋转键数：
  2
• 环数：
  1.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  30.5
• 氢给体数：
  1
• 氢受体数：
  3

反应信息

• 作为反应物：
  描述：

  [1,3,2]dioxaphospholan-2-yl-isopropyl-amine 在 三乙胺 作用下， 以 甲苯 为溶剂， 生成
  参考文献：
  名称：

  Synthesis of Differently Substituted N- and P-Aminodiphosphinoamine PNPN-H Ligands

  摘要：

  On the basis of the known aminodiphosphinoamine ligand Ph2PN(i-Pr)P(Ph) N(i-Pr)-H (3a), differently substituted aminodiphosphinoamine PNPN-H ligands (3) were prepared. By using different synthetic methods, the N-substituted ligands Ph2PN (i-Pr)P(Ph)N(c-Hex)-H (3b), Ph2PN(c-Hex)P(Ph)N(i-Pr)-H (3g), and Ph2PN(i-Pr)P(Ph) N[(CH2)(3)Si(OEt)(3)]-H (3c), in addition to the formerly described Ph2PN(n-Hex)P (Ph)N (i-Pr)-H (3h), Ph2PN(i-Pr)P(Ph)N(Et)-H (3d), Ph2PN(i-Pr)P(Ph)N(Me)-H (3e), and Ph2PN(c-Hex)P(Ph)N(c-Hex)-H (3f), were obtained. In addition, Ph2PN(i-Pr)P(Me)N(i-Pr)-H (3i), (cyclopentyl)(2)PN(i-Pr)P(Ph)N(i-Pr)-H (3j), (-O-CH2-CH2-O-)PN(i-Pr)P(Ph)N(i-Pr)-H (3k), and (1-Ad)(2)PN(i-Pr)P(Ph)N(i-Pr)-H (3l) were prepared with different P-substitutions. All compounds were characterized and the molecular structures of the intermediates Ph2PN(i-Pr)P(Ph)Cl (1a) and (cyclopentyl)(2)PN(i-Pr)P(Ph)Cl (1e) and the ligand (1-Ad)(2)PN(i-Pr)P(Ph)N(i-Pr)-H (3l) were investigated by single-crystal X-ray diffraction. Supplemental materials are available for this article. Go to the publisher's online edition of Phosphorus, Sulfur, and Silicon and the Related Elements to view the free supplemental file.

  DOI：

  10.1080/10426507.2013.807257
• 作为产物：
  描述：

  2-氯-1,3,2-二氧磷杂环戊烷 、 异丙胺 生成 [1,3,2]dioxaphospholan-2-yl-isopropyl-amine
  参考文献：
  名称：

  Synthesis of Differently Substituted N- and P-Aminodiphosphinoamine PNPN-H Ligands

  摘要：

  On the basis of the known aminodiphosphinoamine ligand Ph2PN(i-Pr)P(Ph) N(i-Pr)-H (3a), differently substituted aminodiphosphinoamine PNPN-H ligands (3) were prepared. By using different synthetic methods, the N-substituted ligands Ph2PN (i-Pr)P(Ph)N(c-Hex)-H (3b), Ph2PN(c-Hex)P(Ph)N(i-Pr)-H (3g), and Ph2PN(i-Pr)P(Ph) N[(CH2)(3)Si(OEt)(3)]-H (3c), in addition to the formerly described Ph2PN(n-Hex)P (Ph)N (i-Pr)-H (3h), Ph2PN(i-Pr)P(Ph)N(Et)-H (3d), Ph2PN(i-Pr)P(Ph)N(Me)-H (3e), and Ph2PN(c-Hex)P(Ph)N(c-Hex)-H (3f), were obtained. In addition, Ph2PN(i-Pr)P(Me)N(i-Pr)-H (3i), (cyclopentyl)(2)PN(i-Pr)P(Ph)N(i-Pr)-H (3j), (-O-CH2-CH2-O-)PN(i-Pr)P(Ph)N(i-Pr)-H (3k), and (1-Ad)(2)PN(i-Pr)P(Ph)N(i-Pr)-H (3l) were prepared with different P-substitutions. All compounds were characterized and the molecular structures of the intermediates Ph2PN(i-Pr)P(Ph)Cl (1a) and (cyclopentyl)(2)PN(i-Pr)P(Ph)Cl (1e) and the ligand (1-Ad)(2)PN(i-Pr)P(Ph)N(i-Pr)-H (3l) were investigated by single-crystal X-ray diffraction. Supplemental materials are available for this article. Go to the publisher's online edition of Phosphorus, Sulfur, and Silicon and the Related Elements to view the free supplemental file.

  DOI：

  10.1080/10426507.2013.807257

文献信息

• Synthesis of Differently Substituted N- and P-Aminodiphosphinoamine PNPN-H Ligands
  作者：Marc Gongoll、Bernd H. Müller、Stephan Peitz、Bhaskar R. Aluri、Normen Peulecke、Anke Spannenberg、Uwe Rosenthal、Mohammed H. Al-Hazmi、Anina Wöhl、Wolfgang Müller

  DOI：10.1080/10426507.2013.807257

  日期：2013.12.1

  On the basis of the known aminodiphosphinoamine ligand Ph2PN(i-Pr)P(Ph) N(i-Pr)-H (3a), differently substituted aminodiphosphinoamine PNPN-H ligands (3) were prepared. By using different synthetic methods, the N-substituted ligands Ph2PN (i-Pr)P(Ph)N(c-Hex)-H (3b), Ph2PN(c-Hex)P(Ph)N(i-Pr)-H (3g), and Ph2PN(i-Pr)P(Ph) N[(CH2)(3)Si(OEt)(3)]-H (3c), in addition to the formerly described Ph2PN(n-Hex)P (Ph)N (i-Pr)-H (3h), Ph2PN(i-Pr)P(Ph)N(Et)-H (3d), Ph2PN(i-Pr)P(Ph)N(Me)-H (3e), and Ph2PN(c-Hex)P(Ph)N(c-Hex)-H (3f), were obtained. In addition, Ph2PN(i-Pr)P(Me)N(i-Pr)-H (3i), (cyclopentyl)(2)PN(i-Pr)P(Ph)N(i-Pr)-H (3j), (-O-CH2-CH2-O-)PN(i-Pr)P(Ph)N(i-Pr)-H (3k), and (1-Ad)(2)PN(i-Pr)P(Ph)N(i-Pr)-H (3l) were prepared with different P-substitutions. All compounds were characterized and the molecular structures of the intermediates Ph2PN(i-Pr)P(Ph)Cl (1a) and (cyclopentyl)(2)PN(i-Pr)P(Ph)Cl (1e) and the ligand (1-Ad)(2)PN(i-Pr)P(Ph)N(i-Pr)-H (3l) were investigated by single-crystal X-ray diffraction. Supplemental materials are available for this article. Go to the publisher's online edition of Phosphorus, Sulfur, and Silicon and the Related Elements to view the free supplemental file.