N1-(5-溴吡啶-2-基)乙烷-1,2-二胺 | 4203-89-8

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 氮杂螺癸烷衍生物
• 中文名称: N1-(5-溴吡啶-2-基)乙烷-1,2-二胺
• 中文别名: 2-(1-氧杂-4-氮杂螺[4.5]癸-4-基)乙基甲基丙烯酸酯
• 英文名称: 2-(1-Oxa-4-azaspiro(4.5)dec-4-yl)ethyl methacrylate
• 英文别名: 2-(1-oxa-4-azaspiro[4.5]decan-4-yl)ethyl 2-methylprop-2-enoate
• CAS: 4203-89-8
• 化学式: C₁₄H₂₃NO₃
• 分子量: 253.34
• InChiKey: DCEYPVNNJBGUHA-UHFFFAOYSA-N

物化性质

• 沸点：
  269.32℃[at 101 325 Pa]
• 密度：
  1.06[at 20℃]
• LogP：
  -0.21-3.2 at 20-25℃

计算性质

• 辛醇/水分配系数(LogP)：
  2.5
• 重原子数：
  18
• 可旋转键数：
  5
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.79
• 拓扑面积：
  38.8
• 氢给体数：
  0
• 氢受体数：
  4

安全信息

• 海关编码：
  2934999090

文献信息

• Aqueous coating compositions
  申请人：ROHM AND HAAS COMPANY

  公开号：EP0409459A2

  公开（公告）日：1991-01-23

  An aqueous coating composition comprising an anionically stabilized latex, a polyfunctional amine and a volatile base may be used in or as a road or pavement-marking paint. The compositions demontrate shelf stability and fast cure properties.

  由阴离子稳定胶乳、多官能胺和挥发性基料组成的水性涂料组合物可用于道路或人行道标线涂料。这种组合物具有货架稳定性和快速固化特性。
• Aqueous composition
  申请人：ROHM AND HAAS COMPANY

  公开号：EP0594321A1

  公开（公告）日：1994-04-27

  An aqueous composition is described. The composition comprises a film-forming latex polymer having anionic character ; a water-soluble or water-dispersible polymer formed from at least about 20% by weight monomer containing amine functional groups ; and a volatile base in an amount effective to raise the pH of the composition to a point high enough where essentially all of the amine functional groups are in a nonionic state ; and optionally a water-soluble or water-dispersible multivalent metal. The composition provides an aqueous, quick-set noncementitious composition which is easily applied, develops early cohesive strength and leaves no waste under all curing conditions. The invention is particularly useful as an adhesive used in exterior insulating and finishing systems. The composition also provides an aqueous, exterior, quick-set coating composition having early washout resistance and dirt pick-up resistance. The invention is also particularly useful as a binder used in a traffic paint and as a base coat and/or top coat in exterior insulation finishing systems.

  描述了一种水性组合物。该组合物包括一种具有阴离子特性的成膜胶乳聚合物；一种水溶性或水分散性聚合物，由至少约 20% （按重量计）含有胺官能团的单体形成；以及一种挥发性碱，其用量可有效地将组合物的 pH 值提高到足够高的程度，使所有胺官能团基本上都处于非离子状态；还可选择使用一种水溶性或水分散性多价金属。该组合物提供了一种水性速凝非水泥基组合物，它易于使用，能较早地产生内聚强度，并且在所有固化条件下都不会产生废料。本发明特别适用于室外隔热和饰面系统中的粘合剂。本发明的组合物还提供了一种水性外墙速凝涂料组合物，具有早期耐冲刷性和抗污性。本发明还特别适用于交通涂料中的粘结剂，以及外墙保温饰面系统中的底层涂料和/或面层涂料。
• Preparation of crosslinked anion exchange particles
  申请人：ROHM AND HAAS COMPANY

  公开号：EP0665245A1

  公开（公告）日：1995-08-02

  The present invention provides a process for preparing substantially water-insoluble bile acid sequestrant polymers in particulate form, preferably in spherical form, the polymer particles whenever prepared by such process, and pharmaceutical compositions comprising such polymer particles. The polymer particles, which have a bile acid sequestering efficacy greater than that of cholestyramine, preferably greater than about three times the efficacy of cholestyramine, are prepared by crosslinking one or more amine-containing polymers with one or more polyfunctional amine-reactive compounds. Also disclosed is a method for lowering blood cholesterol level in a mammal comprising oral administration of the polymer particles to the mammal.

  本发明提供了一种制备基本上不溶于水的颗粒状（最好是球形）胆汁酸螯合剂聚合物的工艺，无论何时通过这种工艺制备的聚合物颗粒，以及包含这种聚合物颗粒的药物组合物。这种聚合物颗粒的胆汁酸螯合功效大于胆色素，最好是胆色素的三倍以上，其制备方法是将一种或多种含胺聚合物与一种或多种多官能胺反应化合物交联。还公开了一种降低哺乳动物血液胆固醇水平的方法，包括向哺乳动物口服聚合物颗粒。
• Method of producing wear resistant traffic markings
  申请人：ROHM AND HAAS COMPANY

  公开号：EP0764699A2

  公开（公告）日：1997-03-26

  The present invention is directed to a method of producing wear resistant traffic paint composition. In accordance with the method, a traffic marking of a traffic paint composition having low GPC number average molecular weight latex binder when applied to the road surface exhibits improved wear resistance over those traffic paint compositions having high GPC number average molecular weight latex binders. The wear resistance is further enhanced by modifying the latex polymer used in the composition with acetoacetyl functional pendant moiety and amino silane.

  本发明涉及一种生产耐磨交通涂料组合物的方法。根据该方法，与具有高 GPC 数平均分子量乳胶粘合剂的交通涂料组合物相比，具有低 GPC 数平均分子量乳胶粘合剂的交通涂料组合物涂在路面上的交通标线具有更好的耐磨性。通过对组合物中使用的乳胶聚合物进行乙酰乙酰官能团和氨基硅烷改性，可进一步提高耐磨性。
• Coating composition having extended storage stability
  申请人：ROHM AND HAAS COMPANY

  公开号：EP0832949A2

  公开（公告）日：1998-04-01

  The present invention relates to the preparation of water based coating compositions having extended storage stability. The composition includes separately stored polymeric binder component and a crosslinking component. These components are mixed prior to application over surfaces, such as, road surfaces. The polymeric binder component includes an anionically stabilized binder polymer having at least one reactive functional pendent moiety, or a blend of the binder polymer with a polyfunctional amine. The pot mix of the coating composition has extended storage stability. The waterborne road marking paints of the present invention exhibit improved wear resistance on road surfaces in terms of paint remaining on the road longer than waterborne road marking paints based on the storage stable component alone. The present invention provides road marking paints that can be applied by conventional road striping equipment and do not require special two component spray equipment.

  本发明涉及具有延长储存稳定性的水基涂料组合物的制备。该组合物包括单独储存的聚合物粘合剂成分和交联成分。 这些成分在应用于路面等表面之前进行混合。聚合物粘合剂成分包括阴离子稳定的粘合剂聚合物，该聚合物至少具有一个活性官能团悬垂分子，或粘合剂聚合物与多官能胺的混合物。涂料组合物的罐装混合物具有较长的储存稳定性。本发明的水性道路标线涂料与仅基于储存稳定性成分的水性道路标线涂料相比，在涂料留在路面上的时间更长，从而提高了路面的耐磨性。本发明提供的道路标线涂料可以用传统的道路划线设备涂刷，不需要特殊的双组分喷涂设备。