8-Azaspiro[5.7]tridecane | 67626-13-5

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 氮杂螺癸烷衍生物
• 英文名称: 8-Azaspiro[5.7]tridecane
• CAS: 67626-13-5
• 化学式: C₁₂H₂₃N
• 分子量: 181.32
• InChiKey: HFYMEWLITFWYPH-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.4
• 重原子数：
  13
• 可旋转键数：
  0
• 环数：
  2.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  12
• 氢给体数：
  1
• 氢受体数：
  1

反应信息

• 作为产物：
  描述：

  2-Azaspiro[5.5]undec-1-ene 、 2-Azaspiro[7.5]tridec-1-ene 以3,3-diethyl-3,4,5,6-tetrahydropyridine and 2-azaspiro[5.5]undeca-1,7-diene there is obtained (Example 20A) 2-azaspiro-[7.5]tridecane, b.p. 85°-87° C./0.1 mm的产率得到3,3-diethyl-3,4,5,6-tetrahydropyridine
  参考文献：
  名称：

  2,6-Dimethylpiperidinyl-N-carbobutoxymethyl urea

  摘要：

  本发明涉及一种使用下列式的化合物的方法：##STR1## 其中R.sup.1是氢、烷基或烯基；R.sup.2是氢、烷基、环烷基或单核芳基或R.sup.1和R.sup.2与它们所附着的碳原子一起形成环烷基或环烷氧烷基；R.sup.3是羟基、烷基、烷氧羰基、羟基较低烷基或式的基团：--C(.dbd.Y)NR.sup.4 R.sup.5，其中R.sup.4是氢、烷基、烯基，R.sup.5是烷基、烯基、烷氧基烷基、羰基烷氧基、单核芳基，或R.sup.4和R.sup.5可以与它们所附着的氮原子结合形成具有1至3个杂原子的5至7元杂环；Y是O或S；X是烷基、烷氧羰基烷基或氰基；m是0至2的整数，n和n'是每个具有1至2的整数，虚线表示环中任何位置的可选双键，含有该化合物作为驱虫剂的组合物以及新化合物。

  公开号：

  US04374991A1

文献信息

• Arthropod repellent compositions and methods
  申请人：Rohm and Haas Company

  公开号：US04405630A1

  公开（公告）日：1983-09-20

  This invention relates to a method of using compounds selected from those of the following formula: ##STR1## wherein R.sup.1 is hydrogen, alkyl or alkenyl; R.sup.2 is hydrogen, alkyl, cycloalkyl or mononuclear aryl or R.sup.1 and R.sup.2, taken together with the carbon atom to which they are attached, form a cycloalkyl or cyloalkoxyalkyl; R.sup.3 is hydroxy, alkyl, alkoxycarbonyl, hydroxy lower alkyl or a radical of the formula: --C(.dbd.Y)NR.sup.4 R.sup.5 wherein R.sup.4 is hydrogen, alkyl, or alkenyl, R.sup.5 is alkyl, alkenyl carbalkoxy, or mononuclear aryl, or R.sup.4 and R.sup.5 may be joined together with the nitrogen atom to which they are attached to form a 5- to 7-membered heterocyclic ring having from 1 to 3 hetero atoms; Y is O or S; X is alkyl, alkoxycarbonylalkyl or cyano; m is an integer of 0 to 2 and n and n' are integers each having a value of 1 to 2 and the dotted line indicates an optional carbon to carbon double bond, compositions containing said compounds as insect repellents and to novel compounds.

  本发明涉及一种使用以下式子中选自的化合物的方法：##STR1## 其中R.sup.1是氢，烷基或烯基；R.sup.2是氢，烷基，环烷基或单核芳基或R.sup.1和R.sup.2与它们连接的碳原子一起形成环烷基或环烷氧烷基；R.sup.3是羟基，烷基，烷氧羰基，羟基较低烷基或式子：--C(.dbd.Y)NR.sup.4 R.sup.5的基团，其中R.sup.4是氢，烷基或烯基，R.sup.5是烷基，烯基羧酸烷酯或单核芳基，或R.sup.4和R.sup.5可以与它们连接的氮原子结合形成具有1到3个杂环原子的5-到7成员杂环环；Y是O或S；X是烷基，烷氧羰基烷基或氰基；m是0到2的整数，n和n'是具有1到2的整数值，虚线表示可选的碳到碳双键，含有该化合物作为驱虫剂的组合物以及新化合物。
• Azaspiro compounds
  申请人：Rohm and Haas Company

  公开号：US04400512A1

  公开（公告）日：1983-08-23

  This invention relates to a method of using compounds selected from those of the following formula : ##STR1## wherein R.sup.1 is hydrogen, alkyl or alkenyl; R.sup.2 is hydrogen, alkyl, cycloalkyl or mononuclear aryl or R.sup.1 and R.sup.2, taken together with the carbon atom to which they are attached, form a cycloalkyl or cycloalkoxyalkyl; R.sup.3 is hydroxy, alkyl, alkoxycarbonyl, hydroxy lower alkyl or a radical of the formula: --C(.dbd.Y)NR.sup.4 R.sup.5 wherein R.sup.4 is hydrogen, alkyl, or alkenyl, R.sup.5 is alkyl, alkenyl carbalkoxy, or mononuclear aryl, or R.sup.4 and R.sup.5 may be joined together with the nitrogen atom to which they are attached to form a 5- to 7- membered heterocyclic ring having from 1 to 3 hetero atoms; Y is O or S; X is alkyl, alkoxycarbonylalkyl or cyano; m is an integer of 0 to 2 and n and n' are integers each having a value of 1 to 2 and the dotted line indicates an optional carbon to carbon double bond, compositions containing said compounds as insect repellents and to novel compounds.

  本发明涉及一种使用以下式子中所选化合物的方法： ##STR1## 其中R.sup.1是氢、烷基或烯基；R.sup.2是氢、烷基、环烷基或单核芳基或R.sup.1和R.sup.2与它们所连接的碳原子一起形成环烷基或环烷氧基烷基；R.sup.3是羟基、烷基、烷氧羰基、羟基较低烷基或式子--C(.dbd.Y)NR.sup.4 R.sup.5的基团，其中R.sup.4是氢、烷基或烯基，R.sup.5是烷基、烯基碳酸烷氧基或单核芳基，或R.sup.4和R.sup.5可以与它们所连接的氮原子结合形成具有1至3个杂原子的5-至7-成员杂环；Y是O或S；X是烷基、烷氧羰基烷基或氰基；m是0至2的整数，n和n'是具有1至2的整数值，点线表示可选的碳-碳双键，含有该化合物作为驱虫剂的组合物以及新化合物。
• 2,6-Dimethylpiperidinyl-N-carbobutoxymethyl urea
  申请人：Rohm and Haas Company

  公开号：US04374991A1

  公开（公告）日：1983-02-22

  This invention relates to a method of using compounds of the formula: ##STR1## wherein R.sup.1 is hydrogen, alkyl or alkenyl; R.sup.2 is hydrogen, alkyl, cycloalkyl or mononuclear aryl or R.sup.1 and R.sup.2, taken together with the carbon atom to which they are attached, form a cycloalkyl or cycloalkoxyalkyl; R.sup.3 is hydroxy, alkyl, alkoxycarbonyl, hydroxy lower alkyl or a radical of the formula: --C(.dbd.Y)NR.sup.4 R.sup.5 wherein R.sup.4 is hydrogen, alkyl, alkenyl, R.sup.5 is alkyl, alkenyl, alkoxyalkyl, carbalkoxy, mononuclear aryl, or R.sup.4 and R.sup.5 may be joined together with the nitrogen atom to which they are attached to form a 5 to 7 membered heterocyclic ring having from 1 to 3 hetero atoms; Y is O or S; X is alkyl, alkoxycarbonylalkyl or cyano; m is an integer of 0 to 2 and n and n' are integers each having a value of 1 to 2 and the dotted line indicates an optional double bond anywhere in the ring, compositions containing said compounds as insect repellents and to novel compounds.

  本发明涉及一种使用下列式的化合物的方法：##STR1## 其中R.sup.1是氢、烷基或烯基；R.sup.2是氢、烷基、环烷基或单核芳基或R.sup.1和R.sup.2与它们所附着的碳原子一起形成环烷基或环烷氧烷基；R.sup.3是羟基、烷基、烷氧羰基、羟基较低烷基或式的基团：--C(.dbd.Y)NR.sup.4 R.sup.5，其中R.sup.4是氢、烷基、烯基，R.sup.5是烷基、烯基、烷氧基烷基、羰基烷氧基、单核芳基，或R.sup.4和R.sup.5可以与它们所附着的氮原子结合形成具有1至3个杂原子的5至7元杂环；Y是O或S；X是烷基、烷氧羰基烷基或氰基；m是0至2的整数，n和n'是每个具有1至2的整数，虚线表示环中任何位置的可选双键，含有该化合物作为驱虫剂的组合物以及新化合物。
• US4357471A
  申请人：——

  公开号：US4357471A

  公开（公告）日：1982-11-02
• US4374991A
  申请人：——

  公开号：US4374991A

  公开（公告）日：1983-02-22