[Mg0.75Al0.25(OH)2](NO3)0.25*2H2O

• 分子结构分类: 无机化合物 - 混合金属/非金属化合物 - 后过渡金属氧阴离子化合物
• 英文名称: [Mg0.75Al0.25(OH)2](NO3)0.25*2H2O
• 英文别名: aluminum;magnesium;hydroxide;nitrate;hydrate
• 化学式: 0Al*2HO*2H₂O*0Mg*0NO₃
• 分子量: 110.521
• InChiKey: ACWCJLZZMSLVEX-UHFFFAOYSA-M

计算性质

• 辛醇/水分配系数(LogP)：
  -2.0
• 重原子数：
  8
• 可旋转键数：
  0
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  64.9
• 氢给体数：
  2
• 氢受体数：
  5

反应信息

• 作为反应物：
  描述：

  Na europium(III) decatungstate 、 [Mg0.75Al0.25(OH)2](NO3)0.25*2H2O 在 formamide 作用下， 以 水 为溶剂， 反应 72.0h， 以89%的产率得到
  参考文献：
  名称：

  The application of spontaneous flocculation for the preparation of lanthanide-containing polyoxometalates intercalated layered double hydroxides: highly efficient heterogeneous catalysts for cyanosilylation

  摘要：

  The lanthanide-containing polyoxometalates (POMs) have been intercalated into layered double hydroxides (LDHs) successfully through the spontaneous flocculation method, resulting in the formation of new heterogeneous LDHs-POMs catalysts Mg3Al-LnW(10) (Ln = Eu, Tb and Dy). The synthetic method can prevent Mg2+/Al3+ cations leaching out of the LDHs during intercalation and successfully control the final Mg2+/Al3+ ratio in the corresponding (MgAl)-Al-3-LnW(10). Most importantly, the as-prepared Mg3Al-LnW(10) can be obtained without the formation of the impurity phase. The heterogeneous Mg3Al-EuW10 exhibits highly efficient catalytic reactivity for cyanosilylation of various aldehydes and ketones under solvent-free conditions. The Mg3Al-EuW10 can be easily recovered and reused for at least 10 times without obvious decrease of catalytic activity and the composition and the structure of the Mg3Al-EuW10 catalyst remain stable. Moreover, the Mg3Al-EuW10-catalyzed cyanosilylation of benzaldehyde and hexanal gives the highest TON of 119,950 and 119,906, respectively. (c) 2014 Elsevier B.V. All rights reserved.

  DOI：

  10.1016/j.apcata.2014.09.005
• 作为产物：
  描述：

  hydrotalcite 、 sodium nitrate 在 硝酸 作用下， 以 水 为溶剂， 反应 16.0h， 以90%的产率得到[Mg0.75Al0.25(OH)2](NO3)0.25*2H2O
  参考文献：
  名称：

  层状双氢氧化物中锰（II）-硫杂杯芳烃发光配合物的嵌入：合成和光物理表征

  摘要：

  利用渗透水滑石的肿胀（水滑石，[Mg的1- X的Al X（OH）2 ] X +（NO 3 - ）X）在甲酰胺，阴离子发光配合物[（ThiaSO 2）2（锰II）4在正层之间引入F] -（ThiaSO 2 =对叔丁基磺酰基杯芳烃），导致LDH掺杂。在回收的LDH层中，前体的六边形棱镜形态得到了很好的保留。所得化合物的分子式（Mg 0.71 Al 0.29通过元素和热重分析确定（OH）2（NO 3）0.288（（ThiaSO 2）2（Mn）4 F）0.002（H 2 O）0.5）（1）。低掺杂率归因于配合物的低负电荷密度（eÅ -2）。12.02Å的基本间距表示[（ThiaSO 2）2（Mn II）4 F] -被正LDH层夹在整个宽度上。在固态下研究化合物1的光物理性质。图1示出了在UV激发下的发光性质，在存在和不存在大气O 2的情况下，发射最大值分别集中在630nm和650nm处。已经在不同

  DOI：

  10.1039/d0nj04890a

文献信息

• Classical Keggin Intercalated into Layered Double Hydroxides: Facile Preparation and Catalytic Efficiency in Knoevenagel Condensation Reactions
  作者：Yueqing Jia、Yanjun Fang、Yingkui Zhang、Haralampos N. Miras、Yu-Fei Song

  DOI：10.1002/chem.201501953

  日期：2015.10.12

  Knoevenagel condensation reactions of various aldehydes and ketones with Z‐CH2‐Z′ type substrates (ethyl cyanoacetate and malononitrile) at 60 °C in mixed solvents (V2‐propanol:Vwater=2:1) demonstrated highly efficient catalytic activity. The synergistic effect between the acidic and basic sites of the Mg3Al‐PW12 composite proved to be crucial for the efficiency of the condensation reactions. Additionally

  多金属氧酸盐（POM）插层层状双氢氧化物（LDH）复合材料家族对于设计具有多种应用的功能性材料具有广阔的前景。众所周知，由于空间和几何限制，传统的离子交换方法很难将[PW 12 O 40 ] 3−（PW 12）的经典Keggin多金属氧酸盐（POM）插入层状双氢氧化物（LDHs）中。在本文中，镁这样的插层化合物0.73的Al 0.22（OH）2 [PW 12 ø 40 ] 0.04 ⋅0.98ħ 2 O（Mg的3通过采用自发絮凝方法已成功获得了Al-PW 12）。Mg 3 Al-PW 12已通过多种方法（XRD，SEM，TEM，XPS，EDX，XPS，FT-IR，NMR，BET）进行了全面表征。Mg 3 Al-PW 12的XRD图谱通常在（003）衍射峰附近没有观察到杂质相。中的Mg的后续应用3的Al-PW 12在各种醛和酮与Z-CH Knoevenagel缩合反应催化剂2 -Z'，在60
• IMMUNE MODULATION
  申请人：Austyn Jonathan M.

  公开号：US20130064795A1

  公开（公告）日：2013-03-14

  The invention provides a layered double hydroxide compound for use in modulating an immune response to an antigen, and an immune modulator composition comprising the layered double hydroxide and an antigen. The compound is of formula (I), (II), or (III) [M I M III 2 (OH) 6 ] +[A n− 1/n ]  (I) [M II (1−x) M III x (OH) 2 ] x+ [A n− x/n ]  (II) [M II M III 4 (OH) 12 ][A n− 2/n ]  (III) in which M I is Li + , M II is a divalent metal cation or a mixture of two or more divalent metal cations, M III is a trivalent metal cation or a mixture of two or more trivalent metal cations, or a mixture of one or more trivalent metal cation with one or more quadravalent metal cation, x is from ⅕ to ⅓, and A is an interlayer anion having a charge n, wherein optionally some or all of the interlayer anion A may be replaced by one or biologically active agent and/or one or more antigen, and wherein A is selected from conjugate bases of acids having a pKa of 1 or higher, except for in LDHs of formula (II) when M II comprises Ca 2+ and in LDHs of formula (I), wherein A is selected from conjugate bases of acids having a pKa of −4 or higher.

  该发明提供了一种用于调节抗原免疫反应的分层双氢氧化物化合物，以及包括分层双氢氧化物和抗原的免疫调节剂组合物。该化合物的公式为(I)、(II)或(III)[MIMIII2(OH)6]+[An−1/n]、[MII(1−x)MIIIx(OH)2]x+[An−x/n]和[MIIMIII4(OH)12][An−2/n]，其中MI为Li+，MII为二价金属阳离子或两个或更多二价金属阳离子的混合物，MIII为三价金属阳离子或两个或更多三价金属阳离子的混合物，或一个或多个三价金属阳离子与一个或多个四价金属阳离子的混合物，x为⅕到⅓之间，A是具有电荷n的层间阴离子，其中可选地，一些或所有层间阴离子A可以被一个或多个生物活性剂和/或一个或多个抗原取代，A被选择为具有pKa值大于1的酸的共轭碱基，但在MII包括Ca2+的化合物(II)和在公式(I)的LDHs中，A被选择为具有pKa值大于-4的酸的共轭碱基。
• Green phenol hydroxylation by ultrasonic-assisted synthesized Mg/Cu/Al-LDH catalyst with different molar ratios of Cu2+/Mg2+
  作者：Samar Yusuf、Ahmad Moheb、Mohammad Dinari

  DOI：10.1007/s11164-021-04402-0

  日期：2021.4

  Nitrate-intercalated Mg/Cu/Al-layered double hydroxides (LDHs) were successfully synthesized by the co-precipitation method under ultrasonic irradiation as a fast, simple, and low-cost technique. The LDHs were synthesized with six different molar ratios of Cu2+/Mg2+, and then they were characterized by FT-IR, XRD, TGA, ICP, BET, TEM, and FE-SEM analyses. The results showed that the nitrate ions were well intercalated between layers without any carbonate ions. According to the XRD and TGA results, increasing of Cu ions in the LDHs lowered the crystallization and improved the thermal stability of samples at the same time. The morphological studies carried out by FE-SEM and TEM analyses showed the morphological structure similar to the lamellar structure and plate-like shape particles. However, the surface property of binary LDHs, including Al and only one of Cu or Mg elements, was better than ternary ones. Furthermore, this catalyst was used for the phenol hydroxylation using H2O2 as oxidant and water as a solvent. The results exhibit that the CuMg32Al-NO3− catalyst had the best catalytic activity, as well as it was found that the catalyst is active under mild reaction conditions such as the temperature of 65 °C, phenol: oxidant ratio of 2:1, phenol/catalyst = 100, and reaction time of 1 h. Thus, these conditions gave better activity with the conversion of 27%, the selectivity of 92.05% for catechol and hydroquinone, and CAT/HQ ratio of 1.5.

  在超声波辐照下采用共沉淀法成功合成了硝酸盐夹杂镁/铜/铝层双氢氧化物（LDHs），这是一种快速、简单、低成本的技术。合成了六种不同摩尔比的 Cu2+/Mg2+ 双氢氧化物，并对其进行了 FT-IR、XRD、TGA、ICP、BET、TEM 和 FE-SEM 分析。结果表明，硝酸根离子在层间插层良好，没有碳酸根离子。XRD 和 TGA 结果表明，增加 LDHs 中的铜离子含量可降低结晶度，同时提高样品的热稳定性。通过 FE-SEM 和 TEM 分析进行的形态学研究表明，LDHs 的形态结构类似于片状结构和板状颗粒。然而，二元 LDH（包括 Al 和仅含一种铜或镁元素）的表面性质优于三元 LDH。此外，该催化剂还被用于以 H2O2 为氧化剂、水为溶剂的苯酚羟基化反应。结果表明，CuMg32Al-NO3- 催化剂的催化活性最好，而且在温和的反应条件下，如温度为 65 °C、苯酚与氧化剂的比例为 2:1、苯酚/催化剂=100、反应时间为 1 h，该催化剂也很活跃。因此，在这些条件下，催化剂具有较好的活性，转化率为 27%，对儿茶酚和对苯二酚的选择性为 92.05%，CAT/HQ 比率为 1.5。
• Optical, electrical and dielectric properties of mixed metal oxides derived from Mg-Al Layered Double Hydroxides based solid solution series
  作者：R. Lahkale、R. Sadik、W. Elhatimi、F.Z. Bouragba、A. Assekouri、K. Chouni、O. Rhalmi、E. Sabbar

  DOI：10.1016/j.physb.2021.413367

  日期：2022.2

  In this work, we investigated the aluminum content effect on optical, electrical and dielectric properties of mixed metal oxides (MMOs), derived from calcination at 726 K of solid solution series of nitrate intercalated Mg1-xAlx Layered Doubles Hydroxides (x = 0.167, 0.20, 0.25, 0.33). Subsequently, the MMOs were characterized by X-Ray Diffraction, and analyzed by Inductively Coupled Plasma, Scanning

  在这项工作中，我们研究了铝含量对混合金属氧化物 (MMO) 的光学、电学和介电性能的影响，这些金属氧化物源自在 726 K 下煅烧固溶体系列的硝酸盐插层 Mg 1-x Al x层状双氢氧化物 ( x = 0.167、0.20、0.25、0.33）。随后，MMO 通过 X 射线衍射进行表征，并通过电感耦合等离子体、扫描电子光谱、漫反射光谱和阻抗光谱进行分析。注意到铝含量的增加有利于光的蓝移、高频下介电常数和电导率的增加。较高的铝含量表现出更强的紫外线吸收，平均带隙为 6.29 eV，在可见光-近红外光中具有强光反射率，而较低的铝含量表现出较低的直流离子电导率、介电常数和介电损耗角正切值。此外，报告和讨论了 MMO 的电、介电和光学参数。
• Separation of amino acids by selective sorption through reconstructive intercalation in calcined MgAl-layered double hydroxide
  作者：Bhojaraj、C. Nethravathi、Michael Rajamathi

  DOI：10.1039/d2dt01115h

  日期：——

  selectivity in the intercalation of amino acids (AAs). When the MgAl-LDH derived mixed metal oxide was treated with different mixtures of AAs, preferential sorption of one AA over the other(s) was observed as indicated by XRD analysis of the products and HPLC analysis of the interlayer AA contents in the products. The order of preference was aspartic acid, glutamic acid (acidic AAs) > glycine, alanine (neutral

  Mg-Al 层状双氢氧化物 (MgAl-LDH) 在插入氨基酸 (AAs) 时表现出选择性。当用不同的 AA 混合物处理 MgAl-LDH 衍生的混合金属氧化物时，通过产品的 XRD 分析和产品中层间 AA 含量的 HPLC 分析表明，观察到一种 AA 优先吸附于另一种 AA。优先顺序是天冬氨酸、谷氨酸（酸性AAs）>甘氨酸、丙氨酸（中性AAs）>组氨酸和精氨酸（碱性AAs）。在酸性AA中，天冬氨酸优于谷氨酸，在碱性AA中，组氨酸优于精氨酸。LDH 对甘氨酸和丙氨酸表现出同样的偏好。选择性可以根据 AA 的等电 pH (pI) 来解释。2 . 在某些情况下（如天冬氨酸和甘氨酸）观察到的高选择性会导致单个 AA 从它们的混合物中定量分离。