3-(8-butyl-8-ethyl-2-azaspiro[4.5]decan-2-yl)-N,N-dimethylpropan-1-amine

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 氮杂螺癸烷衍生物
• 英文名称: 3-(8-butyl-8-ethyl-2-azaspiro[4.5]decan-2-yl)-N,N-dimethylpropan-1-amine
• 化学式: C₂₀H₄₀N₂
• 分子量: 308.5
• InChiKey: RZHLBPMWWGVHOV-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  5.8
• 重原子数：
  22
• 可旋转键数：
  8
• 环数：
  2.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  6.5
• 氢给体数：
  0
• 氢受体数：
  2

文献信息

• Method of treating cancer with azaspirane compositions
  申请人：Picker H Donald

  公开号：US20070015780A1

  公开（公告）日：2007-01-18

  A method of treating cancer by administering a therapeutically effective amount of a compound represented by the following Formula (I), or salt, hydrate, or solvate thereof; wherein: n represents a number from 3 to 7; m represents a number from 1 to 2; R 1 and R 2 independently represent a hydrogen atom or are a substituted or unsubstituted, branched or unbranched or cyclic, alkyl provided that the total number of carbon atoms represented by R 1 and R 2 when taken together is no less than 5 and no greater than 10; or R 1 and R 2 together independently represent a cyclic alkyl group having no less than 3 or no more than 7 carbon atoms; R 3 and R 4 independently represent a hydrogen atom or a saturated or unsaturated, substituted or unsubstituted, branched or unbranched or cyclic, hydrocarbyl radical.