1-chlorodimethylaziridine | 83664-41-9

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 氮杂环丙烷
• 英文名称: 1-chlorodimethylaziridine
• 英文别名: 1-chloro-2,2-dimethylaziridine；N-Chlor-2,2-dimethyl-aethylenimin
• CAS: 83664-41-9
• 化学式: C₄H₈ClN
• 分子量: 105.567
• InChiKey: IWSHQPMQKWHWCG-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1
• 重原子数：
  6
• 可旋转键数：
  0
• 环数：
  1.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  3
• 氢给体数：
  0
• 氢受体数：
  1

反应信息

• 作为反应物：
  描述：

  1-chlorodimethylaziridine 在 nickel(II) bis<(3-heptafluorobutanoyl)-(1R)-camphorate> 作用下， 以 gas 为溶剂， 生成 (-)-(R)-1-chloro-2,2-dimethylaziridine 、 (+)-(S)-1-chloro-2,2-dimethylaziridine
  参考文献：
  名称：

  Semi-preparative enantiomer separation of 1-chloro-2,2-dimethylaziridine by complexation gas chromatography -absolute configuration and barrier of inversion

  摘要：

  1-Chloro-2.2-dimethyl-aziridine has been resolved into its enantiomerically pure invertomers by semi-preparative complexation gas chromatography at 25-degrees-C. The absolute configuration has been correlated with the chromatographic elution order. An inversion barrier of DELTA-G-double-ended-dagger = 115.5 kJ/mol was determined in the gas phase at 338.6 K.

  DOI：

  10.1016/s0957-4166(00)82275-2

文献信息

• Semi-preparative enantiomer separation of 1-chloro-2,2-dimethylaziridine by complexation gas chromatography -absolute configuration and barrier of inversion
  作者：Volker Schurig、Ulrich Leyrer

  DOI：10.1016/s0957-4166(00)82275-2

  日期：1990.1

  1-Chloro-2.2-dimethyl-aziridine has been resolved into its enantiomerically pure invertomers by semi-preparative complexation gas chromatography at 25-degrees-C. The absolute configuration has been correlated with the chromatographic elution order. An inversion barrier of DELTA-G-double-ended-dagger = 115.5 kJ/mol was determined in the gas phase at 338.6 K.