p-hydroxybenzyl 2,3,4-tri-O-benzoyl-6-O-levulinyl-β-D-glucopyranoside | 615570-66-6

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 糖脂
• 英文名称: p-hydroxybenzyl 2,3,4-tri-O-benzoyl-6-O-levulinyl-β-D-glucopyranoside
• CAS: 615570-66-6
• 化学式: C₃₉H₃₆O₁₂
• 分子量: 696.708
• InChiKey: XTHWSKPRFJWLRX-LLAXLNJPSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  5.22
• 重原子数：
  51.0
• 可旋转键数：
  14.0
• 环数：
  5.0
• sp3杂化的碳原子比例：
  0.26
• 拓扑面积：
  160.96
• 氢给体数：
  1.0
• 氢受体数：
  12.0

反应信息

• 作为反应物：
  描述：

  ethyl 2,3,4-tri-O-benzoyl-6-O-levulinyl-1-thio-β-D-glucopyranoside 、 p-hydroxybenzyl 2,3,4-tri-O-benzoyl-6-O-levulinyl-β-D-glucopyranoside 生成 4-hydroxybenzyl 2,3,4-tri-O-benzoyl-β-D-(1-6)-glucopyranosyl-2,3,4-tri-O-benzoyl-β-D-(1-6)-glucopyranosyl-2,3,4-tri-O-benzoyl-β-D-(1-6)-glucopyranosyl-2,3,4-tri-O-benzoyl-β-D-glucopyranoside
  参考文献：
  名称：

  Synthesis of Oligosaccharides on Soluble High-Molecular-Weight Branched Polymers in Combination with Purification by Nanofiltration

  摘要：

  An efficient approach for polymer-supported oligosaccharide synthesis is described whereby branched and high-molecular-weight PEG derivatives are used in combination with purification by nanofiltration. This methodology was applied to the preparation of a tetraglucoside and the tumor-associated antigen Le(x).

  DOI：

  10.1021/ol0352355
• 作为产物：
  描述：

  ethyl 2,3,4-tri-O-benzoyl-6-O-levulinyl-1-thio-β-D-glucopyranoside 在 四(三苯基膦)钯 N-碘代丁二酰亚胺 、 三氟甲磺酸三甲基硅酯 、 4 A molecular sieve 作用下， 以 乙醇 、 二氯甲烷 、 水 为溶剂， 反应 6.0h， 生成 p-hydroxybenzyl 2,3,4-tri-O-benzoyl-6-O-levulinyl-β-D-glucopyranoside
  参考文献：
  名称：

  Synthesis of Oligosaccharides on Soluble High-Molecular-Weight Branched Polymers in Combination with Purification by Nanofiltration

  摘要：

  An efficient approach for polymer-supported oligosaccharide synthesis is described whereby branched and high-molecular-weight PEG derivatives are used in combination with purification by nanofiltration. This methodology was applied to the preparation of a tetraglucoside and the tumor-associated antigen Le(x).

  DOI：

  10.1021/ol0352355