1H-Imidazo[2,1-C][1,4]oxazine | 42341-21-9

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 恶嗪类
• 英文名称: 1H-Imidazo[2,1-C][1,4]oxazine
• CAS: 42341-21-9
• 化学式: C₆H₆N₂O
• mdl: MFCD18808116
• 分子量: 122.12
• InChiKey: LIJVUVOUUUNWGT-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.5
• 重原子数：
  9
• 可旋转键数：
  0
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  24.5
• 氢给体数：
  1
• 氢受体数：
  3

文献信息

• ANTIRETROVIRAL AGENTS
  申请人：Gilead Sciences, Inc.

  公开号：EP3186239A1

  公开（公告）日：2017-07-05
• SUBSTITUTED 1,2-DIHYDRO-3H-PYRAZOLO[3,4-D]PYRIMIDIN-3-ONES
  申请人：Recurium IP Holdings, LLC

  公开号：EP3762385A1

  公开（公告）日：2021-01-13
• [EN] ANTIRETROVIRAL AGENTS<br/>[FR] AGENTS ANTIRÉTROVIRAUX
  申请人：GILEAD SCIENCES INC

  公开号：WO2016033243A1

  公开（公告）日：2016-03-03

  Compounds of formula I or salts thereof are disclosed. Also disclosed are pharmaceutical compositions comprising a compound of formula I, processes for preparing compounds of formula I, intermediates useful for preparing compounds of formula I and therapeutic methods for treating a Retroviridae viral infection including an infection caused by the HIV virus.
• [EN] SUBSTITUTED L,2-DIHYDRO-3H-PYRAZOLO[3,4-D]PYRIMIDIN-3-ONES<br/>[FR] L,2-DIHYDRO-3H-PYRAZOLO[3,4-D]PYRIMIDIN-3-ONES SUBSTITUÉES
  申请人：ZENO ROYALTIES & MILESTONES LLC

  公开号：WO2019173082A1

  公开（公告）日：2019-09-12

  Compounds of Formula (I) are provided herein. Such compounds, as well as pharmaceutically acceptable salts and compositions thereof, are useful for treating diseases or conditions, including conditions characterized by excessive cellular proliferation, such as breast cancer.