4,5'-dimethylen-1,1,3,3,2',2',6',6'-octamethyl-1,2,3,4,7,8-hexahydro-6H-pyrano<3,2-c>pyridinespiro<6,3'>-4'-piperidone-2',1-dioxyl | 49581-95-5

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 氮杂螺癸烷衍生物
• 英文名称: 4,5'-dimethylen-1,1,3,3,2',2',6',6'-octamethyl-1,2,3,4,7,8-hexahydro-6H-pyrano<3,2-c>pyridinespiro<6,3'>-4'-piperidone-2',1-dioxyl
• 英文别名: 5,5,7,7,2',2',6',6'-octamethyl-8,5'-bis-methylene-4'-oxo-3,4,7,8-tetrahydro-5H-spiro[pyrano[3,2-c]pyridine-2,3'-piperidine]-6,1'-diyldioxyl
• CAS: 49581-95-5
• 化学式: C₂₂H₃₂N₂O₄
• 分子量: 388.507
• InChiKey: LBNXQPZWGKOQST-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.91
• 重原子数：
  28.0
• 可旋转键数：
  0.0
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.68
• 拓扑面积：
  72.58
• 氢给体数：
  0.0
• 氢受体数：
  4.0

反应信息

• 作为反应物：
  描述：

  4,5'-dimethylen-1,1,3,3,2',2',6',6'-octamethyl-1,2,3,4,7,8-hexahydro-6H-pyrano<3,2-c>pyridinespiro<6,3'>-4'-piperidone-2',1-dioxyl 在 sodium tetrahydroborate 作用下， 以 甲醇 、 苯 为溶剂， 反应 10.0h， 以56.6%的产率得到4-methylene-1,1,3,3,2',2',5',6',6'-nonamethyl-1,2,3,4,7,8-hexahydro-6H-pyrano<3,2-c>pyridinespiro<6,3'>-4'-hydroxypiperidine-2',1-dioxyl
  参考文献：
  名称：

  Chemistry of the dimeric adducts of 3,5-dimethylene-2,2,6,6-tetramethyl-4-piperidone and its paramagnetic N-oxide

  摘要：

  DOI：

  10.1007/bf00951290

文献信息

• Kinetics, mechanism, and reactivity of an activated carbon-carbon double bond in nitroxyl radicals and their diamagnetic analog in interaction with some secondary amines and polyethyleneimine
  作者：A. D. Malievskii、S. V. Koroteev

  DOI：10.1007/bf01431300

  日期：1996.4

  Routes for the reaction of a conjugated methylene group of nitroxyl radicals (NR) with secondary amines were suggested and analyzed. Kinetic parameters of the limiting step of this reaction for the NR-amine and diamagnetic analog of NR-amine systems were estimated. The effect of the medium on these reactions was examined. The specific behavior of polyethyleneimine in the reaction with activated methylene groups of 2,2,6,6-tetramethyl-3,5-dimethylene-4-oxopiperidine-1-oxyl was demonstrated.