硒化钠 | 1313-85-5

• 物质功能分类: 无机化工 - 无机盐 - 硫族化合物
• 分子结构分类: 无机化合物 - 混合金属/非金属化合物 - 各种混合金属/非金属
• 中文名称: 硒化钠
• 英文名称: sodium selenide
• CAS: 1313-85-5
• 化学式: Na₂Se
• 分子量: 124.94
• InChiKey: PNCGYTHKTDMKME-UHFFFAOYSA-N

物化性质

• 熔点：
  >875°C
• 密度：
  2.625
• 溶解度：
  溶于乙醇和液氨。微溶于四氢呋喃。
• 暴露限值：
  ACGIH: TWA 0.2 mg/m3NIOSH: IDLH 1 mg/m3; TWA 0.2 mg/m3
• 稳定性/保质期：

  如果按照规格正确使用和存储，则不会发生分解，也无已知的危险反应。请避免接触氧化物、水分或潮湿环境以及酸性物质。

计算性质

• 辛醇/水分配系数(LogP)：
  -1.14
• 重原子数：
  3
• 可旋转键数：
  0
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  0
• 氢给体数：
  0
• 氢受体数：
  0

安全信息

• TSCA：
  Yes
• 危险等级：
  4.3
• 危险品标志：
  N,T
• 安全说明：
  S20/21,S28,S45,S60,S61
• 危险类别码：
  R50/53,R23/25,R33
• WGK Germany：
  3
• 危险品运输编号：
  UN3134
• RTECS号：
  WE0350000
• 包装等级：
  II
• 危险类别：
  4.3

SDS

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SECTION 1: Identification of the substance/mixture and of the company/undertaking
Product identifiers
Product name : Sodium selenide
REACH No. : A registration number is not available for this substance as the substance
or its uses are exempted from registration, the annual tonnage does not
require a registration or the registration is envisaged for a later
registration deadline.
CAS-No. : 1313-85-5
Relevant identified uses of the substance or mixture and uses advised against
Identified uses : Laboratory chemicals, Manufacture of substances

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SECTION 2: Hazards identification
Classification of the substance or mixture
Classification according to Regulation (EC) No 1272/2008
Acute toxicity, Oral (Category 3), H301
Acute toxicity, Inhalation (Category 3), H331
Specific target organ toxicity - repeated exposure (Category 2), H373
Acute aquatic toxicity (Category 1), H400
Chronic aquatic toxicity (Category 1), H410
For the full text of the H-Statements mentioned in this Section, see Section 16.
Classification according to EU Directives 67/548/EEC or 1999/45/EC
T Toxic R23/25
R33
N Dangerous for the R50/53
environment
For the full text of the R-phrases mentioned in this Section, see Section 16.
Label elements
Labelling according Regulation (EC) No 1272/2008
Pictogram
Signal word Danger
Hazard statement(s)
H301 + H331 Toxic if swallowed or if inhaled
H373 May cause damage to organs through prolonged or repeated exposure.
H410 Very toxic to aquatic life with long lasting effects.
Precautionary statement(s)
P261 Avoid breathing dust.
P273 Avoid release to the environment.
P301 + P310 IF SWALLOWED: Immediately call a POISON CENTER or doctor/
physician.
P311 Call a POISON CENTER or doctor/ physician.
P501 Dispose of contents/ container to an approved waste disposal plant.
Supplemental Hazard none
Statements
Other hazards - none

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SECTION 3: Composition/information on ingredients
Substances
Synonyms : disodium selenide
Formula : Na2Se
Molecular Weight : 124,94 g/mol
CAS-No. : 1313-85-5
EC-No. : 215-212-0
Hazardous ingredients according to Regulation (EC) No 1272/2008
Component Classification Concentration
Sodium selenide
CAS-No. 1313-85-5 Acute Tox. 3; STOT RE 2; <= 100 %
EC-No. 215-212-0 Aquatic Acute 1; Aquatic
Index-No. 034-002-00-8 Chronic 1; H301 + H331,
H373, H410
Hazardous ingredients according to Directive 1999/45/EC
Component Classification Concentration
Sodium selenide
CAS-No. 1313-85-5 T, N, R23/25 - R33 - R50/53 <= 100 %
EC-No. 215-212-0
Index-No. 034-002-00-8
For the full text of the H-Statements and R-Phrases mentioned in this Section, see Section 16

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SECTION 4: First aid measures
Description of first aid measures
General advice
Consult a physician. Show this safety data sheet to the doctor in attendance.
If inhaled
If breathed in, move person into fresh air. If not breathing, give artificial respiration. Consult a physician.
In case of skin contact
Wash off with soap and plenty of water. Take victim immediately to hospital. Consult a physician.
In case of eye contact
Flush eyes with water as a precaution.
If swallowed
Never give anything by mouth to an unconscious person. Rinse mouth with water. Consult a physician.
Most important symptoms and effects, both acute and delayed
The most important known symptoms and effects are described in the labelling (see section 2.2) and/or in
section 11
Indication of any immediate medical attention and special treatment needed
no data available

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SECTION 5: Firefighting measures
Extinguishing media
Suitable extinguishing media
Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide.
Special hazards arising from the substance or mixture
no data available
Advice for firefighters
Wear self contained breathing apparatus for fire fighting if necessary.
Further information
no data available

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SECTION 6: Accidental release measures
Personal precautions, protective equipment and emergency procedures
Wear respiratory protection. Avoid dust formation. Avoid breathing vapours, mist or gas. Ensure
adequate ventilation. Evacuate personnel to safe areas. Avoid breathing dust.
For personal protection see section 8.
Environmental precautions
Prevent further leakage or spillage if safe to do so. Do not let product enter drains. Discharge into the
environment must be avoided.
Methods and materials for containment and cleaning up
Pick up and arrange disposal without creating dust. Sweep up and shovel. Keep in suitable, closed
containers for disposal.
Reference to other sections
For disposal see section 13.

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SECTION 7: Handling and storage
Precautions for safe handling
Avoid contact with skin and eyes. Avoid formation of dust and aerosols.
Provide appropriate exhaust ventilation at places where dust is formed.
For precautions see section 2.2.
Conditions for safe storage, including any incompatibilities
Store in cool place. Keep container tightly closed in a dry and well-ventilated place.
Specific end use(s)
A part from the uses mentioned in section 1.2 no other specific uses are stipulated

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SECTION 8: Exposure controls/personal protection
Control parameters
Components with workplace control parameters
Exposure controls
Appropriate engineering controls
Avoid contact with skin, eyes and clothing. Wash hands before breaks and immediately after handling
the product.
Personal protective equipment
Eye/face protection
Face shield and safety glasses Use equipment for eye protection tested and approved under
appropriate government standards such as NIOSH (US) or EN 166(EU).
Skin protection
Handle with gloves. Gloves must be inspected prior to use. Use proper glove removal technique
(without touching glove's outer surface) to avoid skin contact with this product. Dispose of
contaminated gloves after use in accordance with applicable laws and good laboratory practices.
Wash and dry hands.
The selected protective gloves have to satisfy the specifications of EU Directive 89/686/EEC and
the standard EN 374 derived from it.
Body Protection
Complete suit protecting against chemicals, The type of protective equipment must be selected
according to the concentration and amount of the dangerous substance at the specific workplace.
Respiratory protection
Where risk assessment shows air-purifying respirators are appropriate use a full-face particle
respirator type N100 (US) or type P3 (EN 143) respirator cartridges as a backup to engineering
controls. If the respirator is the sole means of protection, use a full-face supplied air respirator. Use
respirators and components tested and approved under appropriate government standards such
as NIOSH (US) or CEN (EU).
Control of environmental exposure
Prevent further leakage or spillage if safe to do so. Do not let product enter drains. Discharge into
the environment must be avoided.

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SECTION 9: Physical and chemical properties
Information on basic physical and chemical properties
a) Appearance Form: solid
b) Odour no data available
c) Odour Threshold no data available
d) pH no data available
e) Melting point/freezing no data available
point
f) Initial boiling point and no data available
boiling range
g) Flash point no data available
h) Evapouration rate no data available
i) Flammability (solid, gas) no data available
j) Upper/lower no data available
flammability or
explosive limits
k) Vapour pressure no data available
l) Vapour density no data available
m) Relative density 2,625 g/cm3 at 20 °C
n) Water solubility no data available
o) Partition coefficient: n- no data available
octanol/water
p) Auto-ignition no data available
temperature
q) Decomposition no data available
temperature
r) Viscosity no data available
s) Explosive properties no data available
t) Oxidizing properties no data available
Other safety information
no data available

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SECTION 10: Stability and reactivity
Reactivity
no data available
Chemical stability
Stable under recommended storage conditions.
Possibility of hazardous reactions
no data available
Conditions to avoid
no data available
Incompatible materials
Water, Acids, Oxidizing agents
Hazardous decomposition products
Other decomposition products - no data available
In the event of fire: see section 5

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SECTION 11: Toxicological information
Information on toxicological effects
Acute toxicity
LD50 Oral - rat - 13,19 mg/kg
LD50 Oral - mouse - 7,079 mg/kg
LD50 Oral - rabbit - 2,25 mg/kg
LD50 Oral - guinea pig - 5,06 mg/kg
LD50 Intraperitoneal - mouse - 4 mg/kg
Skin corrosion/irritation
no data available
Serious eye damage/eye irritation
no data available
Respiratory or skin sensitisation
no data available
Germ cell mutagenicity
no data available
Carcinogenicity
IARC: 3 - Group 3: Not classifiable as to its carcinogenicity to humans (Sodium selenide)
Reproductive toxicity
no data available
Specific target organ toxicity - single exposure
no data available
Specific target organ toxicity - repeated exposure
May cause damage to organs through prolonged or repeated exposure.
Aspiration hazard
no data available
Additional Information
RTECS: WE0350000
anemia, Vomiting, Diarrhoea, Cough, Difficulty in breathing, Acute selenium poisoning produces central
nervous system effects, which include nervousness, convulsions, and drowsiness. Other signs of
intoxication can include skin eruptions, lassitude, gastrointestinal distress, teeth that are discolored or
decayed, odorous ("garlic") breath, and partial loss of hair and nails. Chronic exposure by inhalation can
produce symptoms that include pallor, coating of the tongue, anemia, irritation of the mucosa, lumbar pain,
liver and spleen damage, as well as any of the other previously mentioned symptoms. Chronic contact with
selenium compounds may cause garlic odor of breath and sweat, dermatitis, and moderate emotional
instability., Dermatitis, garlic-like breath odor, pallor, nervousness, depression

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SECTION 12: Ecological information
Toxicity
no data available
Persistence and degradability
no data available
Bioaccumulative potential
no data available
Mobility in soil
no data available
Results of PBT and vPvB assessment
PBT/vPvB assessment not available as chemical safety assessment not required/not conducted
Other adverse effects
Toxic to aquatic life with long lasting effects.

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SECTION 13: Disposal considerations
Waste treatment methods
Product
Offer surplus and non-recyclable solutions to a licensed disposal company. Dissolve or mix the material
with a combustible solvent and burn in a chemical incinerator equipped with an afterburner and scrubber.
Contaminated packaging
Dispose of as unused product.

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SECTION 14: Transport information
UN number
ADR/RID: 3283 IMDG: 3283 IATA: 3283
UN proper shipping name
ADR/RID: SELENIUM COMPOUND, SOLID, N.O.S. (Sodium selenide)
IMDG: SELENIUM COMPOUND, SOLID, N.O.S. (Sodium selenide)
IATA: Selenium compound, solid, n.o.s. (Sodium selenide)
Transport hazard class(es)
ADR/RID: 6.1 IMDG: 6.1 IATA: 6.1
Packaging group
ADR/RID: II IMDG: II IATA: II
Environmental hazards
ADR/RID: no IMDG Marine pollutant: no IATA: no
Special precautions for user
no data available

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SECTION 15: Regulatory information
This safety datasheet complies with the requirements of Regulation (EC) No. 1907/2006.
Safety, health and environmental regulations/legislation specific for the substance or mixture
no data available
Chemical Safety Assessment
For this product a chemical safety assessment was not carried out

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SECTION 16: Other information
Full text of H-Statements referred to under sections 2 and 3.
Acute Tox. Acute toxicity
Aquatic Acute Acute aquatic toxicity
Aquatic Chronic Chronic aquatic toxicity
H301 Toxic if swallowed.
H301 + H331 Toxic if swallowed or if inhaled
H331 Toxic if inhaled.
H373 May cause damage to organs through prolonged or repeated exposure.
H400 Very toxic to aquatic life.
Full text of R-phrases referred to under sections 2 and 3
N Dangerous for the environment
T Toxic
R23/25 Toxic by inhalation and if swallowed.
R33 Danger of cumulative effects.
R50/53 Very toxic to aquatic organisms, may cause long-term adverse effects in the aquatic
environment.
Further information
Copyright 2013 Co. LLC. License granted to make unlimited paper copies for internal use
only.
The above information is believed to be correct but does not purport to be all inclusive and shall be
used only as a guide. The information in this document is based on the present state of our knowledge
and is applicable to the product with regard to appropriate safety precautions. It does not represent any
guarantee of the properties of the product. Corporation and its Affiliates shall not be held
liable for any damage resulting from handling or from contact with the above product. See
and/or the reverse side of invoice or packing slip for additional terms and conditions of sale.

制备方法与用途

硒化钠（化学式：Na₂Se）是一种白色至红色的晶体，具有吸湿性，在高于875℃时会分解。在水中溶解时会放出硒化氢，并不溶于氨。十水合物为针状固体，在空气中会转变为红色或棕色。

另一种形式为十二水合物（化学式：Na₂Se·6H₂O），呈棱形晶体，熔点为40℃。此物质在空气中易吸收水分和二氧化碳，分解生成碳酸钠和硒。

硒化钠可通过将硒加入到钠的氨溶液中进行制备。

反应信息

• 作为反应物：
  描述：

  硒化钠 、 2,4,6-trimethylphenyl diazonium chloride 以 水 为溶剂， 反应 3.0h， 以60%的产率得到bis(2,4,6-trimethylphenyl) selenide
  参考文献：
  名称：

  Cyclopalladation of dimesityl selenide: synthesis, reactivity, structural characterization, isolation of an intermediate complex with C–H⋯Pd intra-molecular interaction and computational studies

  摘要：

  二甲苯硒化物 (Mes2Se) 与甲苯中的 PdCl2(PhCN)2 或甲苯乙腈中的 PdCl2 反应生成氯桥双核钯络合物，[Pd2Cl2(μ-Cl)2(Mes2Se)2] (1),而在回流乙醇中使用Na2PdCl4，则得到环金属化钯络合物[Pd2(μ-Cl)2{MesSeC6H2(Me2)CH2}2] (2)。当1在乙醇中回流时也可以获得2。在二氯甲烷中用 Pb(Epy)2 处理后，2 得到 Epy 桥联双核配合物，[Pd2(μ-Epy)2{MesSeC6H2(Me2)CH2}2] (3; E = S (3a) 或 Se (3b) ））。用 PPh3 处理 2 产生桥断单体复合物 [PdCl{MesSeC6H2(Me2)CH2}(PPh3)]。通过X射线衍射分析确定了1～3的分子结构。所有配合物都是二聚体，钯原子获得扭曲的方形平面构型。 1 中存在分子内 C–H–Pd 相互作用（dM–H：2.75 × 和

  DOI：

  10.1039/c3dt50935d
• 作为产物：
  描述：

  sodium triethylborohydride 以2%的产率得到
  参考文献：
  名称：

  KOSTER, ROLAND;SEIDEL, GUNTER;BOESE, ROLAND;WRAEKMEYER, BERND, CHEM. BER., 121,(1988) N 11, C. 1955-1966

  摘要：

  DOI：
• 作为试剂：
  描述：

  (E)-2-[bis(ethylsulfanyl)methylidene]-5-(4-chlorophenyl)-3-oxopent-4-enamide 在 硒化钠 作用下， 以 二甲基亚砜 为溶剂， 反应 0.75h， 以72%的产率得到6-(4-chlorophenyl)-2-(ethylthio)-4-oxo-5,6-dihydro-4H-selenopyran-3-carboxamide
  参考文献：
  名称：

  [5C + 1C/N/S/Se] α-烯酰基-α-氨基甲酰基烯酮二硫缩醛的环化：水杨酰胺、烟酰胺和硫代/硒吡喃-3-羧酰胺衍生物的简便合成

  摘要：

  描述了快速获得药学上重要的支架，包括水杨酰胺、二氢烟酰胺和二氢硫基/二氢硒吡喃--3-羧酰胺。α-烯酰基-α-氨基甲酰基烯酮二硫缩醛与碳、氮、硫和硒亲核试剂的 [5+1]-环化反应在温和条件下以高收率得到标题化合物。

  DOI：

  10.1055/s-2008-1067081

文献信息

• MITCHELL R. H., CAN. J. CHEM., 1980, 58, NO 14, 1398-1406
  作者：MITCHELL R. H.

  DOI：——

  日期：——
• MONT, WOLF-W. DU;HENSEL, RALPH;MCFARLANE, WILLIAM;COLQUBOUN, IAN J.;ZIEGL+, CHEM. BER., 122,(1989) N, C. 37-41
  作者：MONT, WOLF-W. DU、HENSEL, RALPH、MCFARLANE, WILLIAM、COLQUBOUN, IAN J.、ZIEGL+

  DOI：——

  日期：——
• ZUBOVICS, ZOLTAN;HEVESI, LASZLO, J. CHEM. SOC. PERKIN TRANS. PT 1,(1988) N, C. 1033-1038
  作者：ZUBOVICS, ZOLTAN、HEVESI, LASZLO

  DOI：——

  日期：——
• BOPOHKOB, M. G.;SOROKIN, M. S.;POTAPOV, V. A., ZH. OBSHCH. XIMII, 60,(1990) N, S. 130-134
  作者：BOPOHKOB, M. G.、SOROKIN, M. S.、POTAPOV, V. A.

  DOI：——

  日期：——
• KAGEYAMA, HIDEKI;TSUTSUMI, HIDEHARU;MURAI, TOSHIAKI;KATO, SHINZI, Z. NATURFORSH. B, 44,(1989) N, C. 1050-1052
  作者：KAGEYAMA, HIDEKI、TSUTSUMI, HIDEHARU、MURAI, TOSHIAKI、KATO, SHINZI

  DOI：——

  日期：——