毒理性
◉ 母乳喂养期间使用总结:本记录中的信息是指将铬酸钠Cr 51作为诊断剂的使用。目前没有关于在母乳喂养期间使用铬酸钠Cr 51的信息。制造商建议在给予诊断剂量的铬酸钠Cr 51后暂停母乳喂养,但并未提供具体的时间长度。由于铬的长生物半衰期和物理半衰期,可能不允许恢复对婴儿的母乳喂养。担心乳汁中放射活性的母亲可以要求在医院核医学科进行检测,当放射性水平达到背景水平时,她们可以安全地恢复母乳喂养。已经发布了一种测量乳汁放射性和确定母亲可以安全恢复母乳喂养时间的方法。[1]
◉ 对哺乳婴儿的影响:截至修订日期,没有找到相关的已发布信息。
◉ 对泌乳和母乳的影响:截至修订日期,没有找到相关的已发布信息。
◉ Summary of Use during Lactation:Information in this record refers to the use of sodium chromate Cr 51 as a diagnostic agent. No information is available on the use of sodium chromate Cr 51 during breastfeeding. The manufacturer recommends withholding breastfeeding after a diagnostic dose of sodium chromate Cr 51, but does not provide a specific duration. The long biological and physical half-lives of chromium may preclude resumption of breastfeeding of the infant. Mothers concerned about the level of radioactivity in their milk could ask to have it tested at a nuclear medicine facility at their hospital and when the radioactivity is at background levels they may safely resume breastfeeding. A method for measuring milk radioactivity and determining the time when a mother can safely resume breastfeeding has been published.[1]
◉ Effects in Breastfed Infants:Relevant published information was not found as of the revision date.
◉ Effects on Lactation and Breastmilk:Relevant published information was not found as of the revision date.
来源:Drugs and Lactation Database (LactMed)