dichloromethylene-phosphoramidic acid diethyl ester | 6185-96-2

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 有机磷酸及其衍生物
• 英文名称: dichloromethylene-phosphoramidic acid diethyl ester
• 英文别名: Phosphorsaeure-diethylester-<(dichlormethylen)-amid>；N-Dichlormethylen-phosphonimidsaeure-diethylester；N-Dichlormethylen-phosphoramidsaeure-diethylester；Phosphorsaeure-diaethylester-dichlormethylenamid；Diethylphosphorsaeure-dichlormethylenamid；Di-Ethoxyphosphoryl-isocyanid-dichlorid；N-(diethoxyphosphinyl)imidocarbonyl dichloride；1,1-dichloro-N-diethoxyphosphorylmethanimine
• CAS: 6185-96-2
• 化学式: C₅H₁₀Cl₂NO₃P
• 分子量: 234.019
• InChiKey: OLKDCUFUZSFZKT-UHFFFAOYSA-N

物化性质

• 沸点：
  81.5-82 °C(Press: 1 Torr)
• 密度：
  1.3181 g/cm3

计算性质

• 辛醇/水分配系数(LogP)：
  2.3
• 重原子数：
  12
• 可旋转键数：
  5
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.8
• 拓扑面积：
  47.9
• 氢给体数：
  0
• 氢受体数：
  4

反应信息

• 作为反应物：
  描述：

  dichloromethylene-phosphoramidic acid diethyl ester 在 formamide 作用下， 生成 N-Diethoxyphosphoryl-N'-diethylharnstoff
  参考文献：
  名称：

  Some reactions of dichloromethyleneamides of dialkylphosphoric acids

  摘要：

  DOI：

  10.1007/bf00854032
• 作为产物：
  描述：

  diethyl phosphorisothiocyanatidate 在 氯 作用下， 生成 dichloromethylene-phosphoramidic acid diethyl ester
  参考文献：
  名称：

  Mono- and diisothiocyanophosphoric acid esters and their derivatives

  摘要：

  DOI：

  10.1007/bf01179595

文献信息

• Derkach,G.I.; Liptuga,N.I., Journal of general chemistry of the USSR, 1966, vol. 36, # 3, p. 480 - 484
  作者：Derkach,G.I.、Liptuga,N.I.

  DOI：——

  日期：——
• Synthesis of cyanamides containing the phenothiazine fragment and their reactions with dialkyldithiophosphoric acids
  作者：R. M. Kamalov、G. M. Makarov、I. A. Litvinov、O. N. Kataeva、M. A. Pudovik、R. A. Cherkasov

  DOI：10.1007/bf00965437

  日期：1991.2

  Reaction of phenothiazine with dialkoxyphosphoryl or chlorosulfenyl isocyanide dichlorides has given 10-cyanophenotiazine, which adds dialkyldithiophosphoric acids at the C = N bond. The addition products rearrange to 10-[N'-(dialkoxythiophosphoryl)thiocarbamoyl]phenothiazines, which are prone to decompose to dialkoxythiophosphoryl isothiocyanates and phenothiazine, or on treatment with alkyl halides in the presence of base afford stable S-alkyl-N-dialkoxythiophosphoryl-(10-phenothiazinyl)isothioformamides. The reaction between 10-cyanophenothiazine and an excess of dithiophosphoric acids also affords 10-thiocarbamoylphenothiazine and tetraalkyl trithiopyrophosphates. An x-ray diffraction examination of the molecular structure of S-methyl-N-diisopropoxythiophosphoryl-(10-phenothiazinyl)isothioformamide has shown it to possess the Z-configuration. The dihedral angle formed by the benzene rings of the phenothiazine fragment is 125.7-degrees. The products of the addition of dithiophosphoric acids to the C = N bond of N,N-bis[2'-(10-phenothiazinyl)-2'-oxoethyl]cyanamide, obtained from 10-(chloroacetyl)phenothiazine and NaNHCN, also isomerize by 1,3S --> N migration of the thiophosphoryl group. Subsequent heterocyclization, with elimination of phenothiazine, affords 2-(dialkoxythiophosphorylimino)-3- [2'-(10-phenothiazinyl)-2'-oxoethyl]thiazolidin-5-ones.
• Dichloromethyleneamides of dialkyl phosphates
  作者：P. I. Alimov、L. N. Levkova

  DOI：10.1007/bf00846514

  日期：1964.5
• Reaction products of dichloromethylenamides of dialkylphosphoric acids with amines and acetic anhydride
  作者：L. A. Antokhina、P. I. Alimov

  DOI：10.1007/bf00923105

  日期：1974.6
• N-phosphorylated alkylisoureas
  作者：M. P. Alimov、P. I. Alimov

  DOI：10.1007/bf00922888

  日期：1969.5