1'-Methylspiro(adamantane-2,3'-pyrrolidine)maleate | 34522-38-8

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 氮杂螺癸烷衍生物
• 英文名称: 1'-Methylspiro(adamantane-2,3'-pyrrolidine)maleate
• 英文别名: (Z)-but-2-enedioic acid;1'-methylspiro[adamantane-2,3'-pyrrolidine]
• CAS: 34522-38-8
• 化学式: C18H27NO4
• 分子量: 321.4
• InChiKey: SWIQYYKGWFIKJQ-BTJKTKAUSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.48
• 重原子数：
  23
• 可旋转键数：
  2
• 环数：
  5.0
• sp3杂化的碳原子比例：
  0.78
• 拓扑面积：
  77.8
• 氢给体数：
  2
• 氢受体数：
  5

文献信息

• COMBINED VIRUSTATIC ANTIMEDIATOR (COVAM) TREATMENT OF COMMON COLDS
  申请人：CENTER FOR INNOVATIVE TECHNOLOGY

  公开号：EP0661967A1

  公开（公告）日：1995-07-12
• EP0661967A4
  申请人：——

  公开号：EP0661967A4

  公开（公告）日：1994-09-29
• EP0768819A4
  申请人：——

  公开号：EP0768819A4

  公开（公告）日：1999-10-13
• ANTIVIRAL EPICATECHINS, EPICATECHIN OLIGOMERS, OR THIOLATED EPICATECHINS FROM THEOBROMA CACAO FOR TREATMENT OF GENITAL WARTS
  申请人：PRESTON Daniel

  公开号：US20110218241A1

  公开（公告）日：2011-09-08

  Epicatechins, Epicatechin Oligomers, or Thiolated Epicatechins are applied (A) directly to a genital wart in the form of a cream, ointment, paste or solution, (B) directly to the genital wart wherein such cream, ointment, paste or solution contains as an additional active ingredient a skin permeabilizing agent, (C) following electrosurgical resection or removal of the genital wart in such form of a cream, ointment, paste or solution, (D) following chemical resection or extirpation of the genital wart in such form, (E) following surgical resection or removal of the genital wart in such form, wherein said Epicatechins, Epicatechin Oligomers, or Thiolated Epicatechins both provide antiviral activity against multiple strains of human papilloma virus (HPV) and promote healing following resection polymers contained in a vehicle. Disclosed are the compositions, therapeutical kits containing such composition, methods of treatment using such composition, and methods of enhancing the stability of such composition.
• US5240694A
  申请人：——

  公开号：US5240694A

  公开（公告）日：1993-08-31