3'-(3-chloro-4-methylphenyl)-quinuclidine-3-spiro-5'-oxazolidine-2',4'-dione trifluoroacetate salt | 917986-59-5

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 氮杂螺癸烷衍生物
• 英文名称: 3'-(3-chloro-4-methylphenyl)-quinuclidine-3-spiro-5'-oxazolidine-2',4'-dione trifluoroacetate salt
• 英文别名: 3'-(3-chloro-4-methylphenyl)-quinuclidine-3-spiro-5'-oxazolidine-2',4'-dione trifluoroacetate；3-(3-Chloro-4-methylphenyl)spiro[1,3-oxazolidine-5,3'-1-azabicyclo[2.2.2]octane]-2,4-dione;2,2,2-trifluoroacetic acid
• CAS: 917986-59-5
• 化学式: C₂HF₃O₂*C₁₆H₁₇ClN₂O₃
• 分子量: 434.8
• InChiKey: ASXXKYAIEMWNCZ-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.23
• 重原子数：
  29
• 可旋转键数：
  1
• 环数：
  5.0
• sp3杂化的碳原子比例：
  0.5
• 拓扑面积：
  87.2
• 氢给体数：
  1
• 氢受体数：
  9

文献信息

• Novel spiro-quinuclidinyl derivatives for the treatment of central nervous system disorders
  申请人：Huang Yifang

  公开号：US20070004715A1

  公开（公告）日：2007-01-04

  The present invention is directed to novel spiro-quinuclidinyl derivatives, pharmaceutical compositions containing them and their use in the treatment of central nervous system disorders.

  本发明涉及新颖的螺环喹啉基衍生物，含有它们的药物组合物以及它们在治疗中枢神经系统疾病中的用途。