diethyl N-(2,2-dimethoxyethyl)-N-methylphosphoramidate | 959925-98-5

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 有机磷酸及其衍生物
• 英文名称: diethyl N-(2,2-dimethoxyethyl)-N-methylphosphoramidate
• CAS: 959925-98-5
• 化学式: C₉H₂₂NO₅P
• 分子量: 255.251
• InChiKey: PCODHYAPVWHFJZ-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.72
• 重原子数：
  16.0
• 可旋转键数：
  9.0
• 环数：
  0.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  57.23
• 氢给体数：
  0.0
• 氢受体数：
  5.0

反应信息

• 作为反应物：
  描述：

  diethyl N-(2,2-dimethoxyethyl)-N-methylphosphoramidate 、 间苯二酚 在 三氟乙酸 作用下， 以 苯 为溶剂， 反应 4.0h， 以50%的产率得到4,6,10,12,16,18,22,24-octahydroxy-2,8,14,20-tetra(N-methylammoniomethyl)pentacyclo[19.3.1.1^3,7.1^9,13.1^15,19]octacosa-1(25),3,5,7(28),9,1,13(27),15,17,19(26),21,23-dodecaene octaethyl tetraphosphate
  参考文献：
  名称：

  Reaction of N-(2,2-Dimethoxyethyl)-N-methylamine and its N-functional derivatives with resorcinol and 2-methylresorcinol. Calix[4]resorcinols functionalized on the lower rim

  摘要：

  Reactions of N-(2,2-Dimethoxyethyl)-N-methylamine and its derivatives with resorcinol and 2-methylresorcinol were studied. Calix[4]resorcinols having aminometyl groups of various structure on the lower rim were obtained.

  DOI：

  10.1134/s1070363207010136
• 作为产物：
  描述：

  氯磷酸二乙酯 、 甲氨基乙醛缩二甲醇 以 苯 为溶剂， 反应 3.0h， 以93.6%的产率得到diethyl N-(2,2-dimethoxyethyl)-N-methylphosphoramidate
  参考文献：
  名称：

  Reaction of N-(2,2-Dimethoxyethyl)-N-methylamine and its N-functional derivatives with resorcinol and 2-methylresorcinol. Calix[4]resorcinols functionalized on the lower rim

  摘要：

  Reactions of N-(2,2-Dimethoxyethyl)-N-methylamine and its derivatives with resorcinol and 2-methylresorcinol were studied. Calix[4]resorcinols having aminometyl groups of various structure on the lower rim were obtained.

  DOI：

  10.1134/s1070363207010136