(3-pentadecylcyclopentyl)methyl diphenyl phosphate | 65148-99-4

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 有机磷酸及其衍生物
• 英文名称: (3-pentadecylcyclopentyl)methyl diphenyl phosphate
• CAS: 65148-99-4
• 化学式: C₃₃H₅₁O₄P
• 分子量: 542.739
• InChiKey: AGQXPIWUENHUSE-UHFFFAOYSA-N

物化性质

• 沸点：
  587.7±23.0 °C(Predicted)
• 密度：
  1.025±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  11.17
• 重原子数：
  38.0
• 可旋转键数：
  21.0
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.64
• 拓扑面积：
  44.76
• 氢给体数：
  0.0
• 氢受体数：
  4.0

反应信息

• 作为反应物：
  描述：

  (3-pentadecylcyclopentyl)methyl diphenyl phosphate 在 platinum(IV) oxide 氢气 作用下， 以 乙醇 为溶剂， 生成 (3-Pentadecylcyclopentyl)methyl dihydrogen phosphate
  参考文献：
  名称：

  Hypotensive phospholipids. Some stable analogs of Darmstoff

  摘要：

  2-Pentadecyl-4-hydroxymethyl-1,3-dioxolane monosodium phosphate (1) has been shown to exhibit bradycardia and hypotension in rats. It is, however, unstable in aqueous solution. In this study, the stable analogues of 1, 2-pentadecyl-5-hydroxymethyltetrahydrofuran monosodium phosphate (7), and 1-hydroxymethyl-3-pentadecylcyclopentane monosodium phosphate (17) were prepared. These substances exhibited cardiovascular effects similar both qualitively and quantitatively to those elicited by 1 and were stable in solution for about 24 and at least 72 h, respectively.

  DOI：

  10.1021/jm00201a001
• 作为产物：
  描述：

  2-Chlor-4-pentadecylcyclohexanon 在 吡啶 、 lithium aluminium tetrahydride 、 sodium 、 苯甲醇 作用下， 以 乙醚 为溶剂， 生成 (3-pentadecylcyclopentyl)methyl diphenyl phosphate
  参考文献：
  名称：

  Hypotensive phospholipids. Some stable analogs of Darmstoff

  摘要：

  2-Pentadecyl-4-hydroxymethyl-1,3-dioxolane monosodium phosphate (1) has been shown to exhibit bradycardia and hypotension in rats. It is, however, unstable in aqueous solution. In this study, the stable analogues of 1, 2-pentadecyl-5-hydroxymethyltetrahydrofuran monosodium phosphate (7), and 1-hydroxymethyl-3-pentadecylcyclopentane monosodium phosphate (17) were prepared. These substances exhibited cardiovascular effects similar both qualitively and quantitatively to those elicited by 1 and were stable in solution for about 24 and at least 72 h, respectively.

  DOI：

  10.1021/jm00201a001