Nucleotide triphosphate probes containing a molecular and/or atomic tag on a a &ggr; and/or &bgr; phosphate group and/or a base moiety having a detectable property are disclosed, and kits and method for using the tagged nucleotides in sequencing reactions and various assay. Also, phosphate and polyphosphate molecular fidelity altering agents are disclosed.
                            本发明公开了含有分子和/或原子标记的
三磷酸核苷酸探针(标记在一个&ggr;和/或&bgr;
磷酸基团和/或具有可检测特性的碱基上),以及在测序反应和各种检测中使用标记核苷酸的试剂盒和方法。此外,还公开了
磷酸和多
磷酸分子保真度改变剂。