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Aspidospermin

中文名称
——
中文别名
——
英文名称
Aspidospermin
英文别名
1-Acetyl-17-methoxyaspidospermidine;1-(12-ethyl-6-methoxy-8,16-diazapentacyclo[10.6.1.01,9.02,7.016,19]nonadeca-2(7),3,5-trien-8-yl)ethanone
Aspidospermin化学式
CAS
——
化学式
C22H30N2O2
mdl
——
分子量
354.492
InChiKey
ARQOGCYMPUOVHK-UHFFFAOYSA-N
BEILSTEIN
——
EINECS
——
  • 物化性质
  • 计算性质
  • ADMET
  • 安全信息
  • SDS
  • 制备方法与用途
  • 上下游信息
  • 反应信息
  • 文献信息
  • 表征谱图
  • 同类化合物
  • 相关功能分类
  • 相关结构分类

计算性质

  • 辛醇/水分配系数(LogP):
    3.4
  • 重原子数:
    26
  • 可旋转键数:
    2
  • 环数:
    5.0
  • sp3杂化的碳原子比例:
    0.68
  • 拓扑面积:
    32.8
  • 氢给体数:
    0
  • 氢受体数:
    3

文献信息

  • [EN] POLYMER SUPPORTED PHOSPHORIC ACIDS AND USE THEREOF AS CATALYSTS IN THE PREPARATION OF 3-INDOLYLMETHANAMINES<br/>[FR] ACIDES PHOSPHORIQUES SUPPORTÉS SUR POLYMÈRES ET LEUR UTILISATION EN TANT QUE CATALYSEURS DANS LA PRÉPARATION DE 3-INDOLYLMÉTHANAMINES
    申请人:FUNDACIÓ INST CATAL D INVESTIGACIÓ QUÍMICA ICIQ
    公开号:WO2015086793A1
    公开(公告)日:2015-06-18
    The present invention relates to the field of catalysis, more particularly to the field of organocatalysis and to polymer supported chiral phosphoric acid catalysts. It also relates to the use of these compounds in the preparation of chiral 3-indolylmethanamines Formula (I).
    本发明涉及催化领域,更具体地涉及有机催化领域和聚合物支持手性磷酸催化剂。它还涉及使用这些化合物制备手性3-吲哚甲胺式(I)的方法。
  • Polymer supported phosphoric acids and use thereof as catalysts in the preparation of 3-indolylmethanamines
    申请人:Fundació Institut Català d'Investigació Química
    公开号:EP2883879A1
    公开(公告)日:2015-06-17
    The present invention relates to the field of catalysis, more particularly to the field of organocatalysis and to polymer supported chiral phosphoric acid catalysts. It also relates to the use of these compounds in the preparation of chiral 3-indolylmethanamines.
    本发明涉及催化领域,更具体地涉及有机催化和聚合物支持手性磷酸催化剂领域。它还涉及在制备手性3-吲哚胺类化合物中使用这些化合物。
  • EXTENDED LIFE SLURRY SEAL COMPOSITION
    申请人:Howe John
    公开号:US20060229389A1
    公开(公告)日:2006-10-12
    Extended life slurry seal compositions with controllable mixing times are prepared by incorporating into a conventional water-asphalt emulsion-aggregate rock system, a slurry life-extending mixture of (i) a polycarboxylate compound aqueous solution, (ii) a polyhydroxy phenolic compound aqueous solution, wherein the phenolic compound is preferably a tannin, tannin derivative, lignin, or lignin derivative, and (iii) a non-aqueous diluent to prevent destabilizing interaction between the polycarboxylate and the polyhydroxy phenolic compound aqueous solution. The polyhydroxy phenolic compound in the aqueous solution may be natural or derived synthetically.
    具有可控混合时间的延长泥浆密封组合物的制备方法是,在传统的-沥青乳液-碎 石系统中加入一种延长泥浆寿命的混合物,该混合物包括(i)聚羧酸化合物溶液,(ii) 聚羟基化合物溶液、其中酚类化合物最好是单宁单宁生物木质素木质素生物,以及 (iii) 非稀释剂,以防止聚羧酸盐和聚羟基酚类化合物溶液之间发生不稳定的相互作用。溶液中的多羟基化合物可以是天然的,也可以是人工合成的。
  • Aqueous buffered fluoride-containing etch residue removers and cleaners
    申请人:——
    公开号:US20040266637A1
    公开(公告)日:2004-12-30
    The invention relates to aqueous, buffered, fluoride containing compositions having a pH of greater than 7.0 to about 11.0. In certain embodiments, the buffered compositions have an extended worklife because pH dependent attributes such as oxide and metal etch rates are stable so long as the pH remains stable.
  • Anti-Inflammatory and Anti-Allergy Extracts from Nettle
    申请人:Alberte Randall S.
    公开号:US20100009927A1
    公开(公告)日:2010-01-14
    The present invention relates in part to nettle extracts that are useful for treating or preventing seasonal allergies, allergic rhinitis, and other inflammatory conditions.
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同类化合物

老刺木素 洛柯因 桥替啶 坚木碱 吡啶-3,4-二羧酸酐 21,O-seco-21,O-Dihydro-hedrantherin 17-methoxy-21-phenoxy-1-propionyl-aspidospermidine N(a)-Methyl-eburinol 2-Hydroxy-3-acetoxymethyl-2-desoxo-3-desmethyoxycarbonyl-vincatin 17-methoxy-21-phenoxy-aspidospermidine 16,17,16',17'-tetraacetoxy-1,1'-diacetyl-[15,15']biaspidospermidinyl 21,0-seco-21,0-Dihydro-17-methoxy-hedrantherin 16-Epi-eburinol 2-Hydroxy-3-hydroxymethyl-2-desoxo-3-desmethyoxycarbonyl-vincatin Vincamsonine Folicangine (-)-14β-hydroxyervinceine Dihydro-obscurinervidindiol-monoacetat O-(p-Jod)benzoyl-demethylvobtusin Ethyl-10-brom-vincadifformat 14-hydroxyervinceine 8-cyano-2,3-didehydro-aspidospermidine-3-carboxylic acid methyl ester Dihydro-neblininolon-acetat Dihydrocimicin 14β-acetoxyvincadifformine 3-acetoxymethyl-1-acetyl-aspidospermidine 15-bromo-16-methoxy-1-methyl-10-oxo-3,4-didehydro-aspidospermidine-3-carboxylic acid methyl ester (6R,6aS,7S,8R,9S)-8-acetoxy-7-ethyl-13a-hydroxy-6-(methoxycarbonyl)-6,7,8,9,10,12,13,13a-octahydro-6,9-methanopyrido[1',2':1,2]azepino[4,5-b]indole 11(6aH)-oxide Dihydrocimicidin jerantinine E acetate Dihydro-neblinin (IIf) 17-hydroxy-1-propionyl-aspidospermidin-21-oic acid methyl ester 3-hydroxymethyl-1-methyl-aspidospermidin-7-ol 3,4-diacetoxy-16-methoxy-1-methyl-10-oxo-aspidospermidine-3-carboxylic acid methyl ester Vincadifformindol 15-bromo-2,20-cyclo-aspidospermidine-3-carboxylic acid methyl ester 7-thioxo-2,3-didehydro-aspidospermidine-3-carboxylic acid ethyl ester Tetrahydrohaplophytin II 16,17,16',17'-tetramethoxy-1',2'-didehydro-[1,15']biaspidospermidinyl 7-oxo-2,3-didehydro-aspidospermidine-3-carboxylic acid ethyl ester Tetrahydroaspidophytin-methylester 20-bromo-2,3-didehydro-aspidospermidine-3-carboxylic acid methyl ester 8-oxo-aspidospermidine-3-carboxylic acid methyl ester 2-Cyano-19-ethoxycarbonyl-19-demethylaspidospermidine Tetrahydrohaplophytin II Methylester 6-hydroxy-1-methyl-aspidospermidine-3-carboxylic acid methyl ester 6-acetoxy-1-methyl-aspidospermidine-3-carboxylic acid methyl ester