1,4-Dihydronicotinamide adenine dinucleotide | 21967-58-8

• 分子结构分类: 有机化合物 - 核苷、核苷酸和类似物 - （5'->5'）-二核苷酸
• 英文名称: 1,4-Dihydronicotinamide adenine dinucleotide
• 英文别名: nadh；O^5'-{2-[1-(3-carbamoyl-4H-pyridin-1-yl)-D-1-deoxy-ribofuranos-5-yloxy]-1,2-dihydroxy-phosphoryl}-adenosine；diphosphoric acid 1-adenosin-5'-yl ester 2-[1-(3-carbamoyl-4H-pyridin-1-yl)-D-1-deoxy-ribofuranos-5-yl] ester；Dihydronicotinamide-adenine dinucleotide；[[5-(6-aminopurin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl] [5-(3-carbamoyl-4H-pyridin-1-yl)-3,4-dihydroxyoxolan-2-yl]methyl hydrogen phosphate
• CAS: 21967-58-8
• 化学式: C₂₁H₂₉N₇O₁₄P₂
• 分子量: 665.447
• InChiKey: BOPGDPNILDQYTO-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -5.7
• 重原子数：
  44
• 可旋转键数：
  11
• 环数：
  5.0
• sp3杂化的碳原子比例：
  0.52
• 拓扑面积：
  318
• 氢给体数：
  8
• 氢受体数：
  19

文献信息

• Use of NAD precursors for breast enhancement
  申请人：UNIVERSITY OF IOWA RESEARCH FOUNDATION

  公开号：US11071747B2

  公开（公告）日：2021-07-27

  Certain embodiments of the invention provide a method for breast enhancement in a female mammal (e.g., a human) in need thereof, comprising administering an effective amount of a nicotinamide adenine dinucleotide (NAD) precursor to the mammal.

  本发明的某些实施方案提供了一种用于需要丰胸的雌性哺乳动物（例如人类）的丰胸方法，包括向哺乳动物施用有效量的烟酰胺腺嘌呤二核苷酸（NAD）前体。
• Charge transfer salts and uses thereof
  申请人：Cambridge Display Technology Limited

  公开号：US11349084B2

  公开（公告）日：2022-05-31

  A charge-transfer salt formed from a material comprising a repeat unit of formula (I) and an n-dopant: wherein BG is a backbone group of the repeat unit; R1 is a ionic substituent comprising at least one cationic or anionic group; n is at least 1; R2 is a non-ionic substituent; and m is 0 or a positive integer; the material further comprising a counterion balancing the charge of the cationic or anionic group.

  一种由包含式（I）重复单元和 n 掺杂剂的材料形成的电荷转移盐：其中 BG 是重复单元的骨架基团；R1 是包含至少一个阳离子或阴离子基团的离子取代基；n 至少为 1；R2 是非离子取代基；m 为 0 或正整数；该材料进一步包含平衡阳离子或阴离子基团电荷的反离子。
• NMR-SOLVE METHOD FOR RAPID IDENTIFICATION OF BI-LIGAND DRUG CANDIDATES
  申请人：Sem S. Daniel

  公开号：US20070298439A1

  公开（公告）日：2007-12-27

  Methods for rapidly identifying drug candidates that can bind to an enzyme at both a common ligand site and a specificity ligand site, resulting in high affinity binding. The bi-ligand drug candidates are screened from a focused combinatorial library where the specific points of variation on a core structure are optimized. The optimal points of variation are identified by which atoms of a ligand bound to the common ligand site are identified to be proximal to the specificity ligand site. As a result, the atoms proximal to the specificity ligand site can then be used as a point for variation to generate a focused combinatorial library of high affinity drug candidates that can bind to both the common ligand site and the specificity ligand site. Different candidates in the library can then have high affinity for many related enzymes sharing a similar common ligand site.
• CARBON NANOTUBE N-DOPING MATERIAL, CARBON NANOTUBE N-DOPING METHOD AND DEVICE USING THE SAME
  申请人：CHOI Jaeyoung

  公开号：US20110215416A1

  公开（公告）日：2011-09-08

  Nicotinamide and/or a compound which is chemically combined with nicotinamide may be used as a carbon nanotube (“CNT”) n-doping material. CNTs n-doped with the CNT n-doping material may have long-lasting doping stability in the air without de-doping. Further, CNT n-doping state may be easily controlled when using the CNT n-doping material. The CNT n-doping material and/or CNTs n-doped with the CNT n-doping material may be used for various applications.
• USE OF NAD PRECURSORS FOR BREAST ENHANCEMENT
  申请人：UNIVERSITY OF IOWA RESEARCH FOUNDATION

  公开号：US20180147225A1

  公开（公告）日：2018-05-31

  Certain embodiments of the invention provide a method for breast enhancement in a female mammal (e.g., a human) in need thereof, comprising administering an effective amount of a nicotinamide adenine dinucleotide (NAD) precursor to the mammal.

表征谱图