N,N-Dimethyl-N-despropionyl-decorticasin | 22143-50-6

• 分子结构分类: 有机化合物 - 生物碱及其衍生物 - 黑麦草碱生物碱及衍生物
• 英文名称: N,N-Dimethyl-N-despropionyl-decorticasin
• 英文别名: ((2R)-(3at,6at)-hexahydro-2r,4c-methano-furo[3,2-b]pyrrol-3c-yl)-dimethyl-amine；N,N-dimethyl-2-oxa-6-azatricyclo[4.2.1.03,7]nonan-8-amine
• CAS: 22143-50-6
• 化学式: C₉H₁₆N₂O
• 分子量: 168.239
• InChiKey: FIWXXQWEVIQSAB-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.1
• 重原子数：
  12
• 可旋转键数：
  1
• 环数：
  3.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  15.7
• 氢给体数：
  0
• 氢受体数：
  3

文献信息

• Endophytes and related methods
  申请人：Agriculture Victoria Services PTY LTD

  公开号：US20170118943A1

  公开（公告）日：2017-05-04

  The present invention relates to a method for identifying and/or characterising an endophyte strain, said method including providing a plurality of samples of endophytes, subjecting said endophytes to genetic analysis, subjecting said endophytes to metabolic analysis and selecting endophytes having a desired genetic and metabolic profile. The present invention also relates to novel endophytes having a desired toxin profile wherein the endophyte produces significantly less toxic alkaloids compared with a control endophyte such as standard toxic (ST) endophyte; and/or significantly more alkaloids conferring beneficial properties compared with a control endophyte such as ST endophyte. The present invention also relates to endophyte variants having a desired genetic and metabolic profile, wherein said endophyte variants possess genetic and/or metabolic characteristics that result in a beneficial phenotype in a plant harbouring or otherwise associated with the endophyte variant. Preferably said endophyte variants are generated by polyploidisation or induced chromosome doubling.
• CONTROL OF PARASITIC INFECTION IN ANIMALS
  申请人：CROPMARK SEEDS LIMITED

  公开号：US20180117056A1

  公开（公告）日：2018-05-03

  The invention relates to the use of alkaloid lolines to reduce parasitic infection in livestock and especially in ruminants, particularly sheep. The loline alkaloids are produced by and found in, grasses infected by endophytes. These grasses can be sown in areas where ruminants graze. Consumption of the grass supports the accumulation of loline alkaloids in the rumen of the animals and leads to a lower rate of infection by internal parasites and hence healthier livestock. The loline alkaloids may be produced by a number of endophytes present in a range of suitable grasses. The invention also provides a range of grasses which are suitable for the treatment of internal infection by parasites in livestock, especially ruminants and more especially sheep.