[5-(3-carbamoyl-4H-pyridin-1-yl)-3,4-dihydroxyoxolan-2-yl]methoxyphosphonic acid

• 分子结构分类: 有机化合物 - 核苷、核苷酸和类似物 - 吡啶核苷酸
• 英文名称: [5-(3-carbamoyl-4H-pyridin-1-yl)-3,4-dihydroxyoxolan-2-yl]methoxyphosphonic acid
• 英文别名: [5-(3-carbamoyl-4H-pyridin-1-yl)-3,4-dihydroxyoxolan-2-yl]methyl dihydrogen phosphate
• 化学式: C₁₁H₁₇N₂O₈P
• 分子量: 336.23
• InChiKey: XQHMUSRSLNRVGA-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -3.2
• 重原子数：
  22
• 可旋转键数：
  5
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.55
• 拓扑面积：
  163
• 氢给体数：
  5
• 氢受体数：
  9

文献信息

• UTILIZING ELECTROMAGNETIC RADIATION TO ACTIVATE FILTERCAKE BREAKERS DOWNHOLE
  申请人：Horton Amy C.

  公开号：US20100263867A1

  公开（公告）日：2010-10-21

  A downhole wellbore filtercake breaker is disclosed comprising one or more breaker chemicals (or activators thereof) capable of being activated with radiation to form one or more breaker reaction products which in turn are capable of reacting with the filtercake to chemically break down the filtercake. There is also disclosed a conventional reservoir drilling fluid modified to include an inactive, delayed, or sequestered breaker chemical or an activator thereof, wherein the breaker chemical (or activator) may be activated directly or indirectly by radiation, such as, microwave, visible, uV, soft x-ray, or other electromagnetic radiation. Also disclosed are methods for creating these filtercakes, and then breaking them via deploying a source of radiation that can be energized proximate to the filtercake. The breaker may be regenerated downhole by reaction with the filtercake breakdown products, and subjected again to a source of radiation to continue the breakdown of filtercake.
• USE OF NAD PRECURSORS FOR BREAST ENHANCEMENT
  申请人：UNIVERSITY OF IOWA RESEARCH FOUNDATION

  公开号：US20180147225A1

  公开（公告）日：2018-05-31

  Certain embodiments of the invention provide a method for breast enhancement in a female mammal (e.g., a human) in need thereof, comprising administering an effective amount of a nicotinamide adenine dinucleotide (NAD) precursor to the mammal.
• USE OF NAD PRECURSORS FOR IMPROVING MATERNAL HEALTH AND/OR OFFSPRING HEALTH
  申请人：UNIVERSITY OF IOWA RESEARCH FOUNDATION

  公开号：US20210106606A1

  公开（公告）日：2021-04-15

  Certain embodiments of the invention provide a method for improving maternal and/or offspring health, comprising administering an effective amount of a nicotinamide adenine dinucleotide (NAD) precursor to a female mammal (e.g., pregnant or lactating female mammal).
• [EN] USE OF NAD PRECURSORS FOR IMPROVING MATERNAL HEALTH AND/OR OFFSPRING HEALTH<br/>[FR] UTILISATION DE PRÉCURSEURS DE NAD POUR AMÉLIORER LA SANTÉ MATERNELLE ET/OU LA SANTÉ DE LA DESCENDANCE
  申请人：UNIV IOWA RES FOUND

  公开号：WO2018102426A1

  公开（公告）日：2018-06-07

  Certain embodiments of the invention provide a method for improving maternal and/or offspring health, comprising administering an effective amount of a nicotinamide adenine dinucleotide (NAD) precursor to a female mammal (e.g., pregnant or lactating female mammal).