Laureth-1 phosphate | 45245-91-8

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 有机磷酸及其衍生物
• 英文名称: Laureth-1 phosphate
• 英文别名: 2-dodecoxyethyl dihydrogen phosphate
• CAS: 45245-91-8
• 化学式: C₁₄H₃₁O₅P
• 分子量: 310.371
• InChiKey: JUFHABKBWMZXKL-UHFFFAOYSA-N

物化性质

• 沸点：
  431.2±47.0 °C(Predicted)
• 密度：
  1.064±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  3.9
• 重原子数：
  20
• 可旋转键数：
  15
• 环数：
  0.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  76
• 氢给体数：
  2
• 氢受体数：
  5

反应信息

• 作为产物：
  描述：

  乙二醇单十二烷基醚 在 三乙胺 、 三氯氧磷 作用下， 以 四氢呋喃 为溶剂， 反应 0.17h， 生成 Laureth-1 phosphate
  参考文献：
  名称：

  Alkyl and Alkoxyethyl Antineoplastic Phospholipids

  摘要：

  Two series of phosphodiester ether lipid analogs with (N-methylmorpholino)ethyl or (N-methylpiperidino)ethyl polar head groups and long aliphatic or alkoxyethyl chains in the nonpolar portion of the molecule were synthesized as potential antineoplastic agents. The cytotoxic activity of these compounds (9-19) was evaluated in vitro against a panel of six human tumor xenografts and in two biochemical, mechanism-based screens (cdc2 kinase and cdc25 phosphatase). Analogs 13, 14, 17, and 19 showed activity in the in vitro tests. Specifically, 14 and 17 were more active than the reference compound hexadecylphosphocholine (Miltefosine, He-PC) while 13 and 19 possessed activity similar to that of the control. Of the analogs tested the one with the highest potency and least toxicity (17) has an N-methylpiperidino head group and a C-16 alkyl chain. In the mechanism-based tests 11 showed weak inhibitory activity in the cdc25 phosphatase screen.

  DOI：

  10.1021/jm9509152

文献信息

• OPTICAL FILTER AND IMAGING APPARATUS
  申请人：Nippon Sheet Glass Company, Limited

  公开号：US20200386928A1

  公开（公告）日：2020-12-10

  An optical filter ( 1 a ) includes a light-absorbing layer ( 10 ). The light-absorbing layer absorbs light in at least a portion of the near-infrared region. When light with a wavelength of 300 to 1200 nm is incident on the optical filter ( 1 a ) at an incident angle of 0°, the optical filter ( 1 a ) satisfies given requirements. When light with a wavelength of 300 to 1200 nm is incident on the optical filter ( 1 a ) at incident angles of 0°, 30°, 35°, and 40°, the optical filter ( 1 a ) satisfies given requirements related to a normalized spectral transmittance. The normalized spectral transmittance is determined by normalization of a spectral transmittance for each incident angle so that the maximum of the spectral transmittance for each incident angle in the wavelength range of 400 to 650 nm is 100%.

  一种光学滤波器（1a）包括一个吸光层（10）。该吸光层吸收至少近红外区域的一部分光线。当波长在300到1200纳米之间的光线以0°入射到光学滤波器（1a）上时，该光学滤波器（1a）满足给定要求。当波长在300到1200纳米之间的光线以0°，30°，35°和40°的入射角度入射到光学滤波器（1a）上时，该光学滤波器（1a）满足与归一化光谱透过率相关的给定要求。归一化光谱透过率是通过对每个入射角度的光谱透过率进行归一化，使得在400到650纳米波长范围内每个入射角度的光谱透过率的最大值为100%来确定的。
• Lubricant for cold plastic working of aluminum alloys
  申请人：HITACHI, LTD.

  公开号：EP0206237A2

  公开（公告）日：1986-12-30

  A lubricating composition comprising (A) at least one member selected from (a) a polyoxyalkylene alkyl ether phosphate diester, (b) a polyoxyalkylene alkylphenyl ether phosphate diester and (c) a phosphonate ester, in an amount of 3% by weight or more, (B) an N,N-ethylenebis acid amide having an average particle size of 1µm or more in an amount of 2 to 15% by weight, and if necessary (C) a lubricating oil having a viscosity of 5 mm2/s or more (40°C) is suitable for cold plastic working of aluminum alloys, particularly age-hardening type aluminum alloys, at the reduction of area of 35% or more.

  一种润滑组合物，包括(A)至少一种选自(a)聚氧亚烷基烷基醚磷酸酯二酯、(b)聚氧亚烷基烷基苯基醚磷酸酯二酯和(c)膦酸酯的成员，其用量为 3%(重量)或更多，(B)一种平均粒径为 1µm 或更大的 N、(C) 粘度为 5 mm2/s 或以上（40°C）的润滑油，适用于铝合金（尤其是时效硬化型铝合金）的冷塑性加工，加工面积减少 35% 或以上。
• Absorbent material and absorbent article
  申请人：DAINIPPON INK AND CHEMICALS, INC.

  公开号：EP1413319A1

  公开（公告）日：2004-04-28

  An absorbent material which comprises an absorbent resin containing a polyacidic amino acid as a constituent component of the resin and having a structure in which primary particles are agglomerated and including pores having a total pore volume as measured by a mercury penetration method of 0.5 to 5.0 cm3/g.

  一种吸水材料，由吸水树脂组成，树脂的组成成分中含有聚酸性氨基酸，其结构为初级颗粒团聚，包括孔隙，根据水银渗透法测量，总孔隙体积为 0.5 至 5.0 cm3/g。
• POLISHING COMPOSITION
  申请人：Showa Denko K.K.

  公开号：EP1870928A1

  公开（公告）日：2007-12-26

  In order to polish a wiring metal, a polishing composition ensuring that etching and erosion are suppressed and the residual wiring metal on the portion other than wiring is decreased, is provided, in which a polishing composition comprising (A) an azole group-containing compound having 3 or more azole groups within the molecule and a molecular weight of 300 to 15,000, (B) an oxidant, and (C) one, two or more acids selected from the group consisting of an amino acid, an organic acid and an inorganic acid is provided.

  为了抛光配线金属，提供了一种抛光组合物，可确保抑制蚀刻和侵蚀，并减少配线以外部分的残余配线金属，其中抛光组合物由以下部分组成：(A) 分子中含有 3 个或 3 个以上唑基且分子量在 300 至 15,000 之间的含唑基化合物；(B) 氧化剂；以及 (C) 一种、两种或两种以上从氨基酸、有机酸和无机酸组成的组中选出的酸。
• METHOD FOR FORMING CONDUCTIVE FILM AND SINTERING PROMOTER
  申请人：Ishihara Chemical Co., Ltd.

  公开号：EP2871645A1

  公开（公告）日：2015-05-13

  In a conductive film forming method using photo sintering, a conductive film having low electric resistance is easily formed. Disclosed is a conductive film forming method in which a conductive film is formed using a photo sintering, which includes the steps of: forming a liquid film 2 made of a copper particulate dispersion on a substrate 1, drying the liquid film 2 to form a copper particulate layer 3, subjecting the copper particulate layer 3 to photo sintering to form a conductive film 4, attaching a sintering promoter 5 to the conductive film 4, and further subjecting the conductive film 4 having the sintering promoter 5 attached to photo sintering. The sintering promoter 5 is a compound which removes copper oxide from metallic copper. Thereby, the sintering promoter 5 removes a surface oxide film of copper particulates 21 in the conductive film 4.

  在使用光烧结的导电膜形成方法中，很容易形成具有低电阻的导电膜。 本发明公开了一种使用光烧结形成导电膜的导电膜形成方法，该方法包括以下步骤：在基板 1 上形成由铜微粒分散体制成的液膜 2，干燥液膜 2 以形成铜微粒层 3，将铜微粒层 3 进行光烧结以形成导电膜 4，在导电膜 4 上附着烧结促进剂 5，以及进一步将附有烧结促进剂 5 的导电膜 4 进行光烧结。烧结促进剂 5 是一种能从金属铜中去除氧化铜的化合物。因此，烧结促进剂 5 可去除导电膜 4 中铜微粒 21 的表面氧化膜。