2',5'-dideoxyadenosine 3'-monophosphate

• 分子结构分类: 有机化合物 - 核苷、核苷酸和类似物 - 核糖核苷3'-磷酸盐
• 英文名称: 2',5'-dideoxyadenosine 3'-monophosphate
• 英文别名: 2',5'-Dideoxy-adenosine 3'-monophosphate；[(2R,3S,5R)-5-(6-aminopurin-9-yl)-2-methyloxolan-3-yl] dihydrogen phosphate
• 化学式: C₁₀H₁₄N₅O₅P
• 分子量: 315.225
• InChiKey: NFGZMOICZSFFLB-DSYKOEDSSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -1
• 重原子数：
  21
• 可旋转键数：
  3
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.5
• 拓扑面积：
  146
• 氢给体数：
  3
• 氢受体数：
  9

文献信息

• COMPOSITION FOR CULTURING MULTIPOTENT STEM CELLS AND UTILIZATION OF THE SAME
  申请人：RIKEN

  公开号：EP1557461A1

  公开（公告）日：2005-07-27

  The invention aims to proliferate or establish undifferentiated pluripotent stem cells that retain their differentiation potency by culturing pluripotent stem cells in a medium free of a feeder cell, or a serum. The aim is attained by using a culture medium for pluripotent stem cells comprising the known ingredients, which is supplemented with an inhibitor of an adenylate cyclase activity.

  本发明旨在通过在不含饲养细胞或血清的培养基中培养多能干细胞，增殖或建立未分化的多能干细胞，以保持其分化潜能。本发明的目的是通过使用由已知成分组成的多能干细胞培养基，并辅以腺苷酸环化酶活性抑制剂来实现的。
• ADP DETECTION BASED LUMINESCENT PHOSPHOTRANSFERASE OR ATP HYDROLASE ASSAY
  申请人：Promega Corporation

  公开号：EP2326953A1

  公开（公告）日：2011-06-01
• METHODS FOR DELAYING OCCURRENCE OF NEW-ONSET TYPE 2 DIABETES AND FOR SLOWING PROGRESSION OF AND TREATING TYPE 2 DIABETES
  申请人：DalCor Pharma UK Ltd Leatherhead, Zug Branch

  公开号：EP3833336A1

  公开（公告）日：2021-06-16
• Composition for culturing multipotent stem cells and utilization of the same
  申请人：Niwa Hitoshi

  公开号：US20060127370A1

  公开（公告）日：2006-06-15

  The invention aims to proliferate or establish undifferentiated pluripotent stem cells that retain their differentiation potency by culturing pluripotent stem cells in a medium free of a feeder cell, or a serum. The aim is attained by using a culture medium for pluripotent stem cells comprising the known ingredients, which is supplemented with an inhibitor of an adenylate cyclase activity.
• ADP detection based luminescent phosphotransferase or ATP hydrolase assay
  申请人：Zegzouti Hicham

  公开号：US20100075350A1

  公开（公告）日：2010-03-25

  The invention provides compositions and methods to determine or detect the activity of enzymes, including phosphotransferases such as kinases (e.g., protein, lipid, and sugar kinases) and ATP hydrolases such as ATPases, e.g., HSP90, that employ ATP as a substrate and form ADP as a product by monitoring changes in ADP.