聚乙二醇十六烷基醚磷酸酯 | 50643-20-4

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 有机磷酸及其衍生物
• 中文名称: 聚乙二醇十六烷基醚磷酸酯
• 中文别名: 磷酸二氢2-(十六烷氧基)乙酯；Α-十六烷基-Ω-羟基聚(氧-1,2-亚乙基)磷酸脂
• 英文名称: Phosphoric acid mono-(2-hexadecyloxy-ethyl) ester
• 英文别名: 2-Hexadecoxyethyl dihydrogen phosphate
• CAS: 50643-20-4
• 化学式: C₁₈H₃₉O₅P
• 分子量: 366.478
• InChiKey: OLORIKAYHUAJHN-UHFFFAOYSA-N

物化性质

• LogP：
  4.943 (est)

计算性质

• 辛醇/水分配系数(LogP)：
  6
• 重原子数：
  24
• 可旋转键数：
  19
• 环数：
  0.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  76
• 氢给体数：
  2
• 氢受体数：
  5

反应信息

• 作为产物：
  描述：

  α-氢化-ω-羟基异十六烷醇聚(氧-1,2-乙烷二基) 在 三乙胺 、 三氯氧磷 作用下， 以 四氢呋喃 为溶剂， 反应 0.17h， 生成 聚乙二醇十六烷基醚磷酸酯
  参考文献：
  名称：

  Alkyl and Alkoxyethyl Antineoplastic Phospholipids

  摘要：

  Two series of phosphodiester ether lipid analogs with (N-methylmorpholino)ethyl or (N-methylpiperidino)ethyl polar head groups and long aliphatic or alkoxyethyl chains in the nonpolar portion of the molecule were synthesized as potential antineoplastic agents. The cytotoxic activity of these compounds (9-19) was evaluated in vitro against a panel of six human tumor xenografts and in two biochemical, mechanism-based screens (cdc2 kinase and cdc25 phosphatase). Analogs 13, 14, 17, and 19 showed activity in the in vitro tests. Specifically, 14 and 17 were more active than the reference compound hexadecylphosphocholine (Miltefosine, He-PC) while 13 and 19 possessed activity similar to that of the control. Of the analogs tested the one with the highest potency and least toxicity (17) has an N-methylpiperidino head group and a C-16 alkyl chain. In the mechanism-based tests 11 showed weak inhibitory activity in the cdc25 phosphatase screen.

  DOI：

  10.1021/jm9509152

文献信息

• Lubricant for cold plastic working of aluminum alloys
  申请人：HITACHI, LTD.

  公开号：EP0206237A2

  公开（公告）日：1986-12-30

  A lubricating composition comprising (A) at least one member selected from (a) a polyoxyalkylene alkyl ether phosphate diester, (b) a polyoxyalkylene alkylphenyl ether phosphate diester and (c) a phosphonate ester, in an amount of 3% by weight or more, (B) an N,N-ethylenebis acid amide having an average particle size of 1µm or more in an amount of 2 to 15% by weight, and if necessary (C) a lubricating oil having a viscosity of 5 mm2/s or more (40°C) is suitable for cold plastic working of aluminum alloys, particularly age-hardening type aluminum alloys, at the reduction of area of 35% or more.

  一种润滑组合物，包括(A)至少一种选自(a)聚氧亚烷基烷基醚磷酸酯二酯、(b)聚氧亚烷基烷基苯基醚磷酸酯二酯和(c)膦酸酯的成员，其用量为 3%(重量)或更多，(B)一种平均粒径为 1µm 或更大的 N、(C) 粘度为 5 mm2/s 或以上（40°C）的润滑油，适用于铝合金（尤其是时效硬化型铝合金）的冷塑性加工，加工面积减少 35% 或以上。
• POLISHING COMPOSITION
  申请人：Showa Denko K.K.

  公开号：EP1870928A1

  公开（公告）日：2007-12-26

  In order to polish a wiring metal, a polishing composition ensuring that etching and erosion are suppressed and the residual wiring metal on the portion other than wiring is decreased, is provided, in which a polishing composition comprising (A) an azole group-containing compound having 3 or more azole groups within the molecule and a molecular weight of 300 to 15,000, (B) an oxidant, and (C) one, two or more acids selected from the group consisting of an amino acid, an organic acid and an inorganic acid is provided.

  为了抛光配线金属，提供了一种抛光组合物，可确保抑制蚀刻和侵蚀，并减少配线以外部分的残余配线金属，其中抛光组合物由以下部分组成：(A) 分子中含有 3 个或 3 个以上唑基且分子量在 300 至 15,000 之间的含唑基化合物；(B) 氧化剂；以及 (C) 一种、两种或两种以上从氨基酸、有机酸和无机酸组成的组中选出的酸。
• COMPOSITION FOR HYDROPHILIC CURED PRODUCT
  申请人：Mitsui Chemicals, Inc.

  公开号：EP3081578A1

  公开（公告）日：2016-10-19

  Objects of the present invention are to provide a composition which can easily give cured products enriched with hydrophilic groups at the surface, and a composition which can give cured products while ensuring that the surface is enriched with hydrophilic groups which are hardly concentrated at the surface by conventional methods; to provide cured products obtained from such compositions; to provide a composition which is suited for producing cured products having high and long-lasting hydrophilicity and also having high surface smoothness; and to provide a cured product obtained from the composition. A monolayer film is fabricated which includes a crosslinked resin obtained by polymerizing a composition including a compound (I) having at least one hydrophilic group selected from anionic hydrophilic groups, cationic hydrophilic groups and hydroxyl groups, and at least one functional group with a polymerizable carbon-carbon double bond (wherein the number of the functional groups with a polymerizable carbon-carbon double bond is one when the hydrophilic group is a hydroxyl-containing group); a compound (II) having two or more functional groups with a polymerizable carbon-carbon double bond (wherein the compound may have a hydroxyl group but is free from anionic hydrophilic groups and cationic hydrophilic groups); and at least one compound selected from a surfactant (III) having a hydrophilic moiety including an anionic hydrophilic group, a cationic hydrophilic group or two or more hydroxyl groups, and a hydrophobic moiety including an organic residue, and a compound (IV) having a siloxane bond and a molecular weight of 200 to 1,000,000 (wherein the surfactant (III) and the compound (IV) have no polymerizable carbon-carbon double bonds). The monolayer film has a gradient of hydrophilic group concentration (Sa/Da) of not less than 1.1 wherein Sa is the surface concentration of at least one type of hydrophilic groups selected from anionic hydrophilic groups, cationic hydrophilic groups and hydroxyl groups, and Da is the deep concentration of the hydrophilic groups at 1/2 of the thickness of the monolayer film.

  本发明的目的是提供一种组合物，该组合物可以很容易地得到表面富含亲水基团的固化产品，以及一种组合物，该组合物可以在得到固化产品的同时确保表面富含亲水基团，而通过传统方法，亲水基团很难集中在表面上；提供由这种组合物得到的固化产品；提供一种组合物，该组合物适合生产具有高且持久亲水性的固化产品，同时还具有高表面光滑度；以及提供由该组合物得到的固化产品。本发明制备了一种单层膜，该单层膜包括通过聚合一种组合物而获得的交联树脂，该组合物包括一种化合物 (I)，该化合物具有至少一个亲水基团，该亲水基团选自阴离子亲水基团、阳离子亲水基团和羟基，以及至少一个具有可聚合碳碳双键的官能团（其中当亲水基团为含羟基基团时，具有可聚合碳碳双键的官能团的数目为一个）；具有两个或两个以上具有可聚合碳碳双键的官能团的化合物 (II)（其中该化合物可具有羟基，但不含阴离子亲水基团和阳离子亲水基团）；以及至少一种选自表面活性剂（III）的化合物，该表面活性剂具有包括阴离子亲水基团、阳离子亲水基团或两个或多个羟基在内的亲水分子，以及包括有机残留物在内的疏水分子，以及具有硅氧烷键且分子量在 200-1,000,000 之间的化合物（IV）（其中表面活性剂（III）和化合物（IV）不具有可聚合的碳碳双键）。单层膜的亲水基团浓度梯度（Sa/Da）不小于 1.1，其中 Sa 是选自阴离子亲水基团、阳离子亲水基团和羟基的至少一种亲水基团的表面浓度，Da 是亲水基团在单层膜厚度的 1/2 处的深度浓度。
• MODIFIED ACRYLIC RESIN CURED PRODUCT, AND LAMINATE THEREOF, AND PRODUCTION METHODS THEREFOR
  申请人：Mitsui Chemicals, Inc.

  公开号：EP3263635A1

  公开（公告）日：2018-01-03

  The purpose of the present invention is to provide a modified acrylic resin cured product, particularly, a modified acrylic resin film, having excellent lubricity and excellent transparency, and a laminate including the modified acrylic resin film. The modified acrylic resin cured product (C) according to the present invention is obtained by treating the surface of a cured product (X) including an acrylic resin by using a compound (A) containing, in each molecule, one or more anionic hydrophilic groups forming an ion pair with an onium ion of an amino silicone, and one or more groups selected from the group consisting of a group containing a polymerizable carbon-carbon double bond, an amino group, a mercapto group and a hydroxy group.

  本发明的目的是提供一种改性丙烯酸树脂固化物，特别是改性丙烯酸树脂薄膜，它具有极佳的润滑性和极佳的透明度，以及一种包括改性丙烯酸树脂薄膜的层压板。根据本发明的改性丙烯酸树脂固化物（C）是通过使用化合物（A）处理包括丙烯酸树脂的固化物（X）的表面而获得的，化合物（A）在每个分子中含有一个或多个阴离子亲水基团，这些基团与氨基硅的鎓离子形成离子对，还含有一个或多个基团，这些基团选自由含有可聚合碳碳双键的基团、氨基、巯基和羟基组成的组。
• HYDROPHILIC SINGLE-LAYER FILM HAVING OPTICAL FUNCTIONALITY, AND LAMINATE THEREOF
  申请人：Mitsui Chemicals, Inc.

  公开号：EP3270192A1

  公开（公告）日：2018-01-17

  In the present invention, there is provided a hydrophilic monolayer film that is excellent in antifogging properties, antifouling properties, the durability of antifogging properties and antifouling properties, and smoothness and that has an antireflective function or a surface structure that serves as a polarizer. There is also provided a method for easily producing such a monolayer film. The monolayer film that is to be produced has a surface structure with multiple protrusions and depressions. The distance between the peaks of adjoining protrusions among such multiple protrusions is in the range of 1 nm to 800 nm. The monolayer film is formed of a crosslinked resin produced by curing of a polymerizable composition that contains a compound having a specific hydrophilic group and a functional group with a polymerizable carbon-carbon double bond and a compound having two or more (meth)acryloyl groups. A gradient of the concentration of hydrophilic groups (Sa2/Da2) in the monolayer film is not less than 1.1 wherein Sa is the concentration of at least one type of hydrophilic groups selected from anionic hydrophilic groups, cationic hydrophilic groups, and a hydroxyl group at the top layer, and Da is the depth concentration of the hydrophilic groups at 1/2 of the thickness of the monolayer film.

  本发明提供了一种亲水单层膜，它在防雾性能、防污性能、防雾性能和防污性能的耐久性以及平滑性方面都非常出色，并且具有防反射功能或可用作偏振器的表面结构。此外，还提供了一种易于生产这种单层薄膜的方法。要生产的单层薄膜具有多突起和凹陷的表面结构。在这些多个突起中，相邻突起的峰值之间的距离在 1 纳米到 800 纳米之间。单层膜由可聚合组合物固化产生的交联树脂形成，该组合物包含具有特定亲水基团和具有可聚合碳碳双键的官能团的化合物以及具有两个或两个以上（甲基）丙烯酰基的化合物。单层膜中亲水基团的浓度梯度(Sa2/Da2)不小于 1.1，其中 Sa 是选自阴离子亲水基团、阳离子亲水基团和羟基的至少一种亲水基团在顶层的浓度，Da 是亲水基团在单层膜厚度 1/2 处的深度浓度。