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    首页 分子通 4-Propan-2-ylthiepane 1,1-dioxide

    4-Propan-2-ylthiepane 1,1-dioxide

    分子结构分类

    有机化合物 - 有机杂环化合物 - 噻庚烷
    中文名称
    ——
    中文别名
    ——
    英文名称
    4-Propan-2-ylthiepane 1,1-dioxide
    英文别名
    4-propan-2-ylthiepane 1,1-dioxide
    4-Propan-2-ylthiepane 1,1-dioxide化学式
    CAS
    ——
    化学式
    C9H18O2S
    mdl
    ——
    分子量
    190.31
    InChiKey
    DIBPPNSURUBCBF-UHFFFAOYSA-N
    BEILSTEIN
    ——
    EINECS
    ——
    • 物化性质
    • 计算性质
    • ADMET
    • 安全信息
    • SDS
    • 制备方法与用途
    • 上下游信息
    • 反应信息
    • 文献信息
    • 表征谱图
    • 同类化合物
    • 相关功能分类
    • 相关结构分类

    计算性质

    • 辛醇/水分配系数(LogP)：
      2
    • 重原子数：
      12
    • 可旋转键数：
      1
    • 环数：
      1.0
    • sp3杂化的碳原子比例：
      1.0
    • 拓扑面积：
      42.5
    • 氢给体数：
      0
    • 氢受体数：
      2

    文献信息

    • Indoleamine 2,3-dioxygenase inhibitor and application
      申请人：Nanjing TransThera Biosciences Co. Ltd.
      公开号：US11046679B2
      公开（公告）日：2021-06-29
      The present invention belongs to the field of medical technology. Particularly, the present invention relates to a compound shown in formula (I), a pharmaceutically acceptable salt thereof, and a stereoisomer of the same. X, Y, Z, R1, R2, R3, R1a, R2a, m, and n are as defined in the specification. The present invention also relates to pharmaceutical preparations and pharmaceutical compositions of these compounds and a use thereof in preparing a drug for treating a related disease mediated by abnormal indoleamine 2,3-dioxygenase (IDO).
      本发明属于医疗技术领域。特别是，本发明涉及一种式（I）所示的化合物、其药学上可接受的盐及其立体异构体。X、Y、Z、R1、R2、R3、R1a、R2a、m 和 n 如说明书中所定义。本发明还涉及这些化合物的药物制剂和药物组合物及其在制备治疗由异常吲哚胺 2，3-二氧 化酶（IDO）介导的相关疾病的药物中的用途。
    • INDOLEAMINE 2,3-DIOXYGENASE INHIBITOR AND APPLICATION
      申请人：Nanjing TransThera Biosciences Co. Ltd.
      公开号：US20200181131A1
      公开（公告）日：2020-06-11
      The present invention belongs to the field of medical technology. Particularly, the present invention relates to a compound shown in formula (I), a pharmaceutically acceptable salt thereof, and a stereoisomer of the same. X, Y, Z, R 1 , R 2 , R 3 , R 1a , R 2a , m, and n are as defined in the specification. The present invention also relates to pharmaceutical preparations and pharmaceutical compositions of these compounds and a use thereof in preparing a drug for treating a related disease mediated by abnormal indoleamine 2,3-dioxygenase (IDO).
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    同类化合物

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