8-Tert-butyl-8-azaspiro[4.5]decane-7,9-dione

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 氮杂螺癸烷衍生物
• 英文名称: 8-Tert-butyl-8-azaspiro[4.5]decane-7,9-dione
• 化学式: C₁₃H₂₁NO₂
• mdl: MFCD08561287
• 分子量: 223.31
• InChiKey: KVHDYSPRYDEJMX-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.2
• 重原子数：
  16
• 可旋转键数：
  1
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.846
• 拓扑面积：
  37.4
• 氢给体数：
  0
• 氢受体数：
  2

文献信息

• ORGANIC COMPOUNDS AND THEIR USES
  申请人：Brandl Trixl

  公开号：US20100204159A1

  公开（公告）日：2010-08-12

  The present application describes organic compounds that are useful for the treatment, prevention and/or amelioration of human diseases.

  本申请描述了对人类疾病的治疗、预防和/或改善有用的有机化合物。
• Substituted pyridinyl and pyrimidinyl derivatives as modulators of metabolism and the treatment of disorders related thereto
  申请人：Arena Pharmaceuticals, Inc.

  公开号：EP1911756A2

  公开（公告）日：2008-04-16

  The present invention relates to certain substituted pyridinyl and pyrimidinyl derivatives of Fomula (Ia) that are modulators of metabolism. Accordingly, compounds of the present invention are useful in the treatment of metabolic-related disorders and complications thereof, such as, diabetes and obesity.

  本发明涉及某些可调节新陈代谢的福莫拉（Ia）取代吡啶基和嘧啶基衍生物。 因此，本发明的化合物可用于治疗代谢相关疾病及其并发症，如糖尿病和肥胖症。
• SUBSTITUTED PYRIDINYL AND PYRIMIDINYL DERIVATIVES AS MODULATORS OF METABOLISM AND THE TREATMENT OF DISORDERS RELATED THERETO
  申请人：Arena Pharmaceuticals, Inc.

  公开号：EP1732562B1

  公开（公告）日：2007-12-19
• SUBSTITUTED ARYL AND HETEROARYL DERIVATIVES AS MODULATORS OF METABOLISM AND THE PROPHYLAXIS AND TREATMENT OF DISORDERS RELATED THERETO
  申请人：Arena Pharmaceuticals, Inc.

  公开号：EP1756084B1

  公开（公告）日：2008-11-26
• Organic Compounds and Their Uses
  申请人：Brandl Trixi

  公开号：US20070286842A1

  公开（公告）日：2007-12-13

  The present application describes organic compounds that are useful for the treatment, prevention and/or amelioration of human diseases.