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    —— tert-butyl N-[(2S)-1-[5-[2-(1H-indazol-6-ylamino)-4-(3-methoxypropylamino)pyrimidin-5-yl]pent-4-ynylamino]-1-oxopropan-2-yl]-N-methylcarbamate —— C29H40N8O4
    tert-butyl N-[(2S)-1-[5-[2-(1H-indazol-6-ylamino)-4-(3-methoxypropylamino)pyrimidin-5-yl]pent-4-ynylamino]-1-oxopropan-2-yl]-N-methylcarbamate
    —— tert-butyl N-[(2S)-1-[5-[2-(1H-indazol-5-ylamino)-4-(3-methoxypropylamino)pyrimidin-5-yl]pent-4-ynylamino]-1-oxopropan-2-yl]-N-methylcarbamate —— C29H40N8O4
    tert-butyl N-[(2S)-1-[5-[2-(1H-indazol-5-ylamino)-4-(3-methoxypropylamino)pyrimidin-5-yl]pent-4-ynylamino]-1-oxopropan-2-yl]-N-methylcarbamate
    —— tert-butyl N-[(2S)-1-[5-[2-(3-fluoro-4-methoxyanilino)-4-(propylamino)pyrimidin-5-yl]pent-4-ynylamino]-1-oxopropan-2-yl]-N-methylcarbamate —— C28H39FN6O4
    tert-butyl N-[(2S)-1-[5-[2-(3-fluoro-4-methoxyanilino)-4-(propylamino)pyrimidin-5-yl]pent-4-ynylamino]-1-oxopropan-2-yl]-N-methylcarbamate
    —— tert-butyl (2S,4R)-2-[5-[2-(3-fluoroanilino)-4-(propylamino)pyrimidin-5-yl]pent-4-ynylcarbamoyl]-4-methoxypyrrolidine-1-carboxylate —— C29H39FN6O4
    tert-butyl (2S,4R)-2-[5-[2-(3-fluoroanilino)-4-(propylamino)pyrimidin-5-yl]pent-4-ynylcarbamoyl]-4-methoxypyrrolidine-1-carboxylate
    —— tert-butyl N-[(2S)-1-[5-[2-(3-fluoroanilino)-4-[(6-methoxypyridin-3-yl)amino]pyrimidin-5-yl]pent-4-ynylamino]-1-oxopropan-2-yl]-N-methylcarbamate —— C30H36FN7O4
    tert-butyl N-[(2S)-1-[5-[2-(3-fluoroanilino)-4-[(6-methoxypyridin-3-yl)amino]pyrimidin-5-yl]pent-4-ynylamino]-1-oxopropan-2-yl]-N-methylcarbamate
    —— tert-butyl N-methyl-N-[(2S)-1-[5-[2-[(6-methylpyridin-3-yl)amino]-4-(propylamino)pyrimidin-5-yl]pent-4-ynylamino]-1-oxopropan-2-yl]carbamate —— C27H39N7O3
    tert-butyl N-methyl-N-[(2S)-1-[5-[2-[(6-methylpyridin-3-yl)amino]-4-(propylamino)pyrimidin-5-yl]pent-4-ynylamino]-1-oxopropan-2-yl]carbamate
    —— tert-butyl N-[(2S)-1-[5-[2-(1H-indazol-6-ylamino)-4-(methylamino)pyrimidin-5-yl]pent-4-ynylamino]-1-oxopropan-2-yl]-N-methylcarbamate —— C26H34N8O3
    tert-butyl N-[(2S)-1-[5-[2-(1H-indazol-6-ylamino)-4-(methylamino)pyrimidin-5-yl]pent-4-ynylamino]-1-oxopropan-2-yl]-N-methylcarbamate
    —— tert-butyl N-[(2S)-1-[5-[2-[(6-fluoropyridin-3-yl)amino]-4-pyrrolidin-1-ylpyrimidin-5-yl]pent-4-ynylamino]-1-oxopropan-2-yl]-N-methylcarbamate —— C27H36FN7O3
    tert-butyl N-[(2S)-1-[5-[2-[(6-fluoropyridin-3-yl)amino]-4-pyrrolidin-1-ylpyrimidin-5-yl]pent-4-ynylamino]-1-oxopropan-2-yl]-N-methylcarbamate
    —— tert-butyl N-methyl-N-[(2S)-1-[5-[2-(2-methylpropylamino)-4-(propylamino)pyrimidin-5-yl]pent-4-ynylamino]-1-oxopropan-2-yl]carbamate —— C25H42N6O3
    tert-butyl N-methyl-N-[(2S)-1-[5-[2-(2-methylpropylamino)-4-(propylamino)pyrimidin-5-yl]pent-4-ynylamino]-1-oxopropan-2-yl]carbamate
    —— tert-butyl N-[(2S)-1-[5-[2-(3-fluoroanilino)-4-(propylamino)pyrimidin-5-yl]pent-4-ynylamino]-3-methyl-1-oxopentan-2-yl]-N-methylcarbamate —— C30H43FN6O3
    tert-butyl N-[(2S)-1-[5-[2-(3-fluoroanilino)-4-(propylamino)pyrimidin-5-yl]pent-4-ynylamino]-3-methyl-1-oxopentan-2-yl]-N-methylcarbamate
    —— tert-butyl N-[(2S)-1-[5-[2-(3-fluoroanilino)-4-(propylamino)pyrimidin-5-yl]pent-4-ynylamino]-1-oxopentan-2-yl]-N-methylcarbamate —— C29H41FN6O3
    tert-butyl N-[(2S)-1-[5-[2-(3-fluoroanilino)-4-(propylamino)pyrimidin-5-yl]pent-4-ynylamino]-1-oxopentan-2-yl]-N-methylcarbamate
    —— tert-butyl N-[2-[5-[2-(4-cyanoanilino)-4-(propylamino)pyrimidin-5-yl]pent-4-ynylamino]-2-oxoethyl]-N-methylcarbamate —— C27H35N7O3
    tert-butyl N-[2-[5-[2-(4-cyanoanilino)-4-(propylamino)pyrimidin-5-yl]pent-4-ynylamino]-2-oxoethyl]-N-methylcarbamate
    —— tert-butyl N-methyl-N-[(2S)-1-[[(1S,3R)-3-[2-[2-(methylamino)-4-(propylamino)pyrimidin-5-yl]ethynyl]cyclohexyl]amino]-1-oxopropan-2-yl]carbamate —— C25H40N6O3
    tert-butyl N-methyl-N-[(2S)-1-[[(1S,3R)-3-[2-[2-(methylamino)-4-(propylamino)pyrimidin-5-yl]ethynyl]cyclohexyl]amino]-1-oxopropan-2-yl]carbamate
    —— tert-butyl N-[(2S)-1-[5-[2-(3-fluoroanilino)-4-(quinolin-6-ylamino)pyrimidin-5-yl]pent-4-ynylamino]-1-oxopropan-2-yl]-N-methylcarbamate —— C33H36FN7O3
    tert-butyl N-[(2S)-1-[5-[2-(3-fluoroanilino)-4-(quinolin-6-ylamino)pyrimidin-5-yl]pent-4-ynylamino]-1-oxopropan-2-yl]-N-methylcarbamate
    —— tert-butyl (2S)-2-[5-[2-(1H-indazol-6-ylamino)-4-(methylamino)pyrimidin-5-yl]pent-4-ynylcarbamoyl]pyrrolidine-1-carboxylate —— C27H34N8O3
    tert-butyl (2S)-2-[5-[2-(1H-indazol-6-ylamino)-4-(methylamino)pyrimidin-5-yl]pent-4-ynylcarbamoyl]pyrrolidine-1-carboxylate
    —— tert-butyl N-[(2S)-1-[5-[2-(4-carbamoylanilino)-4-pyrrolidin-1-ylpyrimidin-5-yl]pent-4-ynylamino]-1-oxopropan-2-yl]-N-methylcarbamate —— C29H39N7O4
    tert-butyl N-[(2S)-1-[5-[2-(4-carbamoylanilino)-4-pyrrolidin-1-ylpyrimidin-5-yl]pent-4-ynylamino]-1-oxopropan-2-yl]-N-methylcarbamate
    —— tert-butyl N-[(2S)-1-[5-[4-(cyclopropylamino)-2-(1H-indazol-5-ylamino)pyrimidin-5-yl]pent-4-ynylamino]-1-oxopropan-2-yl]-N-methylcarbamate —— C28H36N8O3
    tert-butyl N-[(2S)-1-[5-[4-(cyclopropylamino)-2-(1H-indazol-5-ylamino)pyrimidin-5-yl]pent-4-ynylamino]-1-oxopropan-2-yl]-N-methylcarbamate
    —— tert-butyl N-[(3S)-1-[5-[2-(3-fluoroanilino)-4-(propylamino)pyrimidin-5-yl]pent-4-ynyl]-5-methyl-2-oxopyrrolidin-3-yl]-N-methylcarbamate —— C29H39FN6O3
    tert-butyl N-[(3S)-1-[5-[2-(3-fluoroanilino)-4-(propylamino)pyrimidin-5-yl]pent-4-ynyl]-5-methyl-2-oxopyrrolidin-3-yl]-N-methylcarbamate
    —— tert-butyl methyl (2-oxo-2-((3-(4-(propylamino)-2-(3-(pyridin-4-yl)ureido)pyrimidine-5-carboxamido)propyl)amino)ethyl)carbamate —— C25H37N9O5
    tert-butyl methyl (2-oxo-2-((3-(4-(propylamino)-2-(3-(pyridin-4-yl)ureido)pyrimidine-5-carboxamido)propyl)amino)ethyl)carbamate
    —— tert-butyl N-[3-[2-[2-(3-fluoroanilino)-4-(methylamino)pyrimidin-5-yl]ethynyl]cyclobutyl]carbamate —— C22H26FN5O2
    tert-butyl N-[3-[2-[2-(3-fluoroanilino)-4-(methylamino)pyrimidin-5-yl]ethynyl]cyclobutyl]carbamate
    —— tert-butyl N-[(2S)-1-[5-[2-[(2-fluoropyridin-4-yl)amino]-4-(propylamino)pyrimidin-5-yl]pent-4-ynylamino]-1-oxopropan-2-yl]-N-methylcarbamate —— C26H36FN7O3
    tert-butyl N-[(2S)-1-[5-[2-[(2-fluoropyridin-4-yl)amino]-4-(propylamino)pyrimidin-5-yl]pent-4-ynylamino]-1-oxopropan-2-yl]-N-methylcarbamate
    —— tert-butyl (2S)-2-[5-[2-(3-fluoro-4-methoxyanilino)-4-(methylamino)pyrimidin-5-yl]pent-4-ynylcarbamoyl]pyrrolidine-1-carboxylate —— C27H35FN6O4
    tert-butyl (2S)-2-[5-[2-(3-fluoro-4-methoxyanilino)-4-(methylamino)pyrimidin-5-yl]pent-4-ynylcarbamoyl]pyrrolidine-1-carboxylate
    —— tert-butyl (2S)-2-[5-[2-(4-cyanoanilino)-4-(methylamino)pyrimidin-5-yl]pent-4-ynylcarbamoyl]pyrrolidine-1-carboxylate —— C27H33N7O3
    tert-butyl (2S)-2-[5-[2-(4-cyanoanilino)-4-(methylamino)pyrimidin-5-yl]pent-4-ynylcarbamoyl]pyrrolidine-1-carboxylate
    —— tert-butyl N-[(2S)-1-[5-[4-(4-cyanoanilino)-2-(3-fluoroanilino)pyrimidin-5-yl]pent-4-ynylamino]-1-oxopropan-2-yl]-N-methylcarbamate —— C31H34FN7O3
    tert-butyl N-[(2S)-1-[5-[4-(4-cyanoanilino)-2-(3-fluoroanilino)pyrimidin-5-yl]pent-4-ynylamino]-1-oxopropan-2-yl]-N-methylcarbamate
    —— tert-butyl N-[3-[2-[2-(4-fluoroanilino)-4-(propylamino)pyrimidin-5-yl]ethynyl]cyclobutyl]carbamate —— C24H30FN5O2
    tert-butyl N-[3-[2-[2-(4-fluoroanilino)-4-(propylamino)pyrimidin-5-yl]ethynyl]cyclobutyl]carbamate
    —— tert-butyl N-[(2S)-1-[5-[2-[(6-fluoropyridin-3-yl)amino]-4-(propylamino)pyrimidin-5-yl]pent-4-ynylamino]-1-oxopropan-2-yl]-N-methylcarbamate —— C26H36FN7O3
    tert-butyl N-[(2S)-1-[5-[2-[(6-fluoropyridin-3-yl)amino]-4-(propylamino)pyrimidin-5-yl]pent-4-ynylamino]-1-oxopropan-2-yl]-N-methylcarbamate
    —— tert-butyl N-[(2S)-1-[5-[2-[[5-fluoro-6-(methylamino)pyridin-3-yl]amino]-4-(propylamino)pyrimidin-5-yl]pent-4-ynylamino]-1-oxopropan-2-yl]-N-methylcarbamate —— C27H39FN8O3
    tert-butyl N-[(2S)-1-[5-[2-[[5-fluoro-6-(methylamino)pyridin-3-yl]amino]-4-(propylamino)pyrimidin-5-yl]pent-4-ynylamino]-1-oxopropan-2-yl]-N-methylcarbamate
    —— tert-butyl (2S,4S)-2-[5-[2-(3-fluoroanilino)-4-(propylamino)pyrimidin-5-yl]pent-4-ynylcarbamoyl]-4-methoxypyrrolidine-1-carboxylate —— C29H39FN6O4
    tert-butyl (2S,4S)-2-[5-[2-(3-fluoroanilino)-4-(propylamino)pyrimidin-5-yl]pent-4-ynylcarbamoyl]-4-methoxypyrrolidine-1-carboxylate
    —— tert-butyl N-[2-[2-methyl-5-[[4-(propylamino)-2-(2-pyridin-4-ylethylamino)pyrimidine-5-carbonyl]amino]anilino]-2-oxoethyl]carbamate —— C29H38N8O4
    tert-butyl N-[2-[2-methyl-5-[[4-(propylamino)-2-(2-pyridin-4-ylethylamino)pyrimidine-5-carbonyl]amino]anilino]-2-oxoethyl]carbamate
    —— tert-butyl N-methyl-N-[(2S)-1-[5-[4-(methylamino)-2-[(1-methylindazol-6-yl)amino]pyrimidin-5-yl]pent-4-ynylamino]-1-oxopropan-2-yl]carbamate —— C27H36N8O3
    tert-butyl N-methyl-N-[(2S)-1-[5-[4-(methylamino)-2-[(1-methylindazol-6-yl)amino]pyrimidin-5-yl]pent-4-ynylamino]-1-oxopropan-2-yl]carbamate
    —— tert-butyl (2S)-2-[5-[4-(cyclopropylamino)-2-(1H-indazol-6-ylamino)pyrimidin-5-yl]pent-4-ynylcarbamoyl]pyrrolidine-1-carboxylate —— C29H36N8O3
    tert-butyl (2S)-2-[5-[4-(cyclopropylamino)-2-(1H-indazol-6-ylamino)pyrimidin-5-yl]pent-4-ynylcarbamoyl]pyrrolidine-1-carboxylate
    —— tert-butyl N-[(2S)-1-[[(1S,3R)-3-[2-[2-(4-fluoroanilino)-4-(propylamino)pyrimidin-5-yl]ethynyl]cyclohexyl]amino]-1-oxopropan-2-yl]-N-methylcarbamate —— C30H41FN6O3
    tert-butyl N-[(2S)-1-[[(1S,3R)-3-[2-[2-(4-fluoroanilino)-4-(propylamino)pyrimidin-5-yl]ethynyl]cyclohexyl]amino]-1-oxopropan-2-yl]-N-methylcarbamate
    —— tert-butyl (2S)-2-[5-[2-(4-fluoroanilino)-4-(methylamino)pyrimidin-5-yl]pent-4-ynylcarbamoyl]pyrrolidine-1-carboxylate —— C26H33FN6O3
    tert-butyl (2S)-2-[5-[2-(4-fluoroanilino)-4-(methylamino)pyrimidin-5-yl]pent-4-ynylcarbamoyl]pyrrolidine-1-carboxylate
    —— tert-butyl N-[(2S)-1-[5-[2-[(6-fluoropyridin-3-yl)amino]-4-morpholin-4-ylpyrimidin-5-yl]pent-4-ynylamino]-1-oxopropan-2-yl]-N-methylcarbamate —— C27H36FN7O4
    tert-butyl N-[(2S)-1-[5-[2-[(6-fluoropyridin-3-yl)amino]-4-morpholin-4-ylpyrimidin-5-yl]pent-4-ynylamino]-1-oxopropan-2-yl]-N-methylcarbamate
    —— tert-butyl N-methyl-N-[(2S)-1-oxo-1-[5-[4-(propylamino)-2-[3-(trifluoromethoxy)anilino]pyrimidin-5-yl]pent-4-ynylamino]propan-2-yl]carbamate —— C28H37F3N6O4
    tert-butyl N-methyl-N-[(2S)-1-oxo-1-[5-[4-(propylamino)-2-[3-(trifluoromethoxy)anilino]pyrimidin-5-yl]pent-4-ynylamino]propan-2-yl]carbamate
    —— tert-butyl (2S)-2-[5-[4-(ethylamino)-2-(1H-indazol-5-ylamino)pyrimidin-5-yl]pent-4-ynylcarbamoyl]pyrrolidine-1-carboxylate —— C28H36N8O3
    tert-butyl (2S)-2-[5-[4-(ethylamino)-2-(1H-indazol-5-ylamino)pyrimidin-5-yl]pent-4-ynylcarbamoyl]pyrrolidine-1-carboxylate
    —— tert-butyl N-[(2S)-1-[5-[2-[(5-tert-butyl-1,2-oxazol-3-yl)amino]-4-(propylamino)pyrimidin-5-yl]pent-4-ynylamino]-1-oxopropan-2-yl]-N-methylcarbamate —— C28H43N7O4
    tert-butyl N-[(2S)-1-[5-[2-[(5-tert-butyl-1,2-oxazol-3-yl)amino]-4-(propylamino)pyrimidin-5-yl]pent-4-ynylamino]-1-oxopropan-2-yl]-N-methylcarbamate
    —— tert-butyl N-[(2S)-1-[5-[2-(3-cyanoanilino)-4-morpholin-4-ylpyrimidin-5-yl]pent-4-ynylamino]-1-oxopropan-2-yl]-N-methylcarbamate —— C29H37N7O4
    tert-butyl N-[(2S)-1-[5-[2-(3-cyanoanilino)-4-morpholin-4-ylpyrimidin-5-yl]pent-4-ynylamino]-1-oxopropan-2-yl]-N-methylcarbamate
    —— tert-butyl N-[2-[5-[2-(4-cyanoanilino)-4-(propylamino)pyrimidin-5-yl]pent-4-ynoylamino]ethyl]-N-methylcarbamate —— C27H35N7O3
    tert-butyl N-[2-[5-[2-(4-cyanoanilino)-4-(propylamino)pyrimidin-5-yl]pent-4-ynoylamino]ethyl]-N-methylcarbamate
    —— tert-butyl N-[(2S)-1-[5-[2-(cyclopropylamino)-4-(propylamino)pyrimidin-5-yl]pent-4-ynylamino]-1-oxopropan-2-yl]-N-methylcarbamate —— C24H38N6O3
    tert-butyl N-[(2S)-1-[5-[2-(cyclopropylamino)-4-(propylamino)pyrimidin-5-yl]pent-4-ynylamino]-1-oxopropan-2-yl]-N-methylcarbamate
    —— tert-butyl (2S)-2-[5-[4-(cyclopropylamino)-2-(1H-indazol-5-ylamino)pyrimidin-5-yl]pent-4-ynylcarbamoyl]pyrrolidine-1-carboxylate —— C29H36N8O3
    tert-butyl (2S)-2-[5-[4-(cyclopropylamino)-2-(1H-indazol-5-ylamino)pyrimidin-5-yl]pent-4-ynylcarbamoyl]pyrrolidine-1-carboxylate
    —— tert-butyl N-[(2S)-1-[5-[2-(3-fluoroanilino)-4-(propylamino)pyrimidin-5-yl]pent-4-ynylamino]-1-oxobutan-2-yl]-N-methylcarbamate —— C28H39FN6O3
    tert-butyl N-[(2S)-1-[5-[2-(3-fluoroanilino)-4-(propylamino)pyrimidin-5-yl]pent-4-ynylamino]-1-oxobutan-2-yl]-N-methylcarbamate
    —— tert-butyl ((S)-1-(((1S,3R)-3-((2-((2-fluoropyridin-4-yl)amino)-4-(propylamino)pyrimidin-5-yl)ethynyl)cyclohexyl)amino)-1-oxopropan-2-yl)(methyl)carbamate —— C29H40FN7O3
    tert-butyl ((S)-1-(((1S,3R)-3-((2-((2-fluoropyridin-4-yl)amino)-4-(propylamino)pyrimidin-5-yl)ethynyl)cyclohexyl)amino)-1-oxopropan-2-yl)(methyl)carbamate
    —— tert-butyl N-[3-[2-[2-(3-cyanoanilino)-4-(methylamino)pyrimidin-5-yl]ethynyl]cyclobutyl]carbamate —— C23H26N6O2
    tert-butyl N-[3-[2-[2-(3-cyanoanilino)-4-(methylamino)pyrimidin-5-yl]ethynyl]cyclobutyl]carbamate
    —— tert-butyl (2S)-2-[5-[2-(1H-indazol-6-ylamino)-4-(3-methoxypropylamino)pyrimidin-5-yl]pent-4-ynylcarbamoyl]pyrrolidine-1-carboxylate —— C30H40N8O4
    tert-butyl (2S)-2-[5-[2-(1H-indazol-6-ylamino)-4-(3-methoxypropylamino)pyrimidin-5-yl]pent-4-ynylcarbamoyl]pyrrolidine-1-carboxylate
    —— tert-butyl N-[(2S)-1-[[5-[2-(4-cyanoanilino)-4-(propylamino)pyrimidin-5-yl]-3,3-dimethylpent-4-ynyl]amino]-1-oxopropan-2-yl]-N-methylcarbamate —— C30H41N7O3
    tert-butyl N-[(2S)-1-[[5-[2-(4-cyanoanilino)-4-(propylamino)pyrimidin-5-yl]-3,3-dimethylpent-4-ynyl]amino]-1-oxopropan-2-yl]-N-methylcarbamate
    —— tert-butyl N-[(2S)-1-[5-[2-chloro-4-(propylamino)pyrimidin-5-yl]pent-4-ynylamino]-1-oxopropan-2-yl]carbamate —— C20H30ClN5O3
    tert-butyl N-[(2S)-1-[5-[2-chloro-4-(propylamino)pyrimidin-5-yl]pent-4-ynylamino]-1-oxopropan-2-yl]carbamate
    —— tert-butyl N-[(2S)-1-[5-[2-(3-cyanoanilino)-4-[methyl(propyl)amino]pyrimidin-5-yl]pent-4-ynylamino]-1-oxopropan-2-yl]-N-methylcarbamate —— C29H39N7O3
    tert-butyl N-[(2S)-1-[5-[2-(3-cyanoanilino)-4-[methyl(propyl)amino]pyrimidin-5-yl]pent-4-ynylamino]-1-oxopropan-2-yl]-N-methylcarbamate
    —— tert-butyl N-[(2S)-1-[5-[4-(cyclopropylamino)-2-(1H-indazol-6-ylamino)pyrimidin-5-yl]pent-4-ynylamino]-1-oxopropan-2-yl]-N-methylcarbamate —— C28H36N8O3
    tert-butyl N-[(2S)-1-[5-[4-(cyclopropylamino)-2-(1H-indazol-6-ylamino)pyrimidin-5-yl]pent-4-ynylamino]-1-oxopropan-2-yl]-N-methylcarbamate
    —— tert-butyl N-[(2S)-1-[5-[4-(ethylamino)-2-(1H-indazol-6-ylamino)pyrimidin-5-yl]pent-4-ynylamino]-1-oxopropan-2-yl]-N-methylcarbamate —— C27H36N8O3
    tert-butyl N-[(2S)-1-[5-[4-(ethylamino)-2-(1H-indazol-6-ylamino)pyrimidin-5-yl]pent-4-ynylamino]-1-oxopropan-2-yl]-N-methylcarbamate