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    —— ethyl (6R)-6-(3-chlorophenyl)-3-methyl-4-[[4-(4-methylbenzoyl)piperazin-1-yl]methyl]-2-oxo-1,6-dihydropyrimidine-5-carboxylate —— C27H31ClN4O4
    ethyl (6R)-6-(3-chlorophenyl)-3-methyl-4-[[4-(4-methylbenzoyl)piperazin-1-yl]methyl]-2-oxo-1,6-dihydropyrimidine-5-carboxylate
    —— ethyl (6S)-4-[[4-(cyclopropanecarbonyl)-1,4-diazepan-1-yl]methyl]-6-(2-fluorophenyl)-3-methyl-2-oxo-1,6-dihydropyrimidine-5-carboxylate —— C24H31FN4O4
    ethyl (6S)-4-[[4-(cyclopropanecarbonyl)-1,4-diazepan-1-yl]methyl]-6-(2-fluorophenyl)-3-methyl-2-oxo-1,6-dihydropyrimidine-5-carboxylate
    —— ethyl (6R)-6-(3-chlorophenyl)-4-[[(3R)-4-(furan-2-carbonyl)-3-methylpiperazin-1-yl]methyl]-3-methyl-2-oxo-1,6-dihydropyrimidine-5-carboxylate —— C25H29ClN4O5
    ethyl (6R)-6-(3-chlorophenyl)-4-[[(3R)-4-(furan-2-carbonyl)-3-methylpiperazin-1-yl]methyl]-3-methyl-2-oxo-1,6-dihydropyrimidine-5-carboxylate
    —— ethyl (6R)-6-(4-chlorophenyl)-2-oxo-4-(piperidin-1-ylmethyl)-3-prop-2-enyl-1,6-dihydropyrimidine-5-carboxylate —— C22H28ClN3O3
    ethyl (6R)-6-(4-chlorophenyl)-2-oxo-4-(piperidin-1-ylmethyl)-3-prop-2-enyl-1,6-dihydropyrimidine-5-carboxylate
    —— ethyl (6R)-3-ethyl-2-oxo-4-(pyrrolidin-1-ylmethyl)-6-[2-(trifluoromethyl)phenyl]-1,6-dihydropyrimidine-5-carboxylate —— C21H26F3N3O3
    ethyl (6R)-3-ethyl-2-oxo-4-(pyrrolidin-1-ylmethyl)-6-[2-(trifluoromethyl)phenyl]-1,6-dihydropyrimidine-5-carboxylate
    —— ethyl (6S)-4-[[4-(cyclopropanecarbonyl)piperazin-1-yl]methyl]-6-(3,4-dimethoxyphenyl)-3-ethyl-2-oxo-1,6-dihydropyrimidine-5-carboxylate —— C26H36N4O6
    ethyl (6S)-4-[[4-(cyclopropanecarbonyl)piperazin-1-yl]methyl]-6-(3,4-dimethoxyphenyl)-3-ethyl-2-oxo-1,6-dihydropyrimidine-5-carboxylate
    —— ethyl (6R)-4-[[(3R)-4-(3-fluorobenzoyl)-3-methylpiperazin-1-yl]methyl]-6-(2-methoxyphenyl)-3-methyl-2-oxo-1,6-dihydropyrimidine-5-carboxylate —— C28H33FN4O5
    ethyl (6R)-4-[[(3R)-4-(3-fluorobenzoyl)-3-methylpiperazin-1-yl]methyl]-6-(2-methoxyphenyl)-3-methyl-2-oxo-1,6-dihydropyrimidine-5-carboxylate
    —— ethyl (6R)-6-(3-chlorophenyl)-4-[[4-(furan-2-carbonyl)piperazin-1-yl]methyl]-3-methyl-2-oxo-1,6-dihydropyrimidine-5-carboxylate —— C24H27ClN4O5
    ethyl (6R)-6-(3-chlorophenyl)-4-[[4-(furan-2-carbonyl)piperazin-1-yl]methyl]-3-methyl-2-oxo-1,6-dihydropyrimidine-5-carboxylate
    —— ethyl (6R)-4-[(4-ethoxycarbonylpiperidin-1-yl)methyl]-6-(3-methoxyphenyl)-3-methyl-2-oxo-1,6-dihydropyrimidine-5-carboxylate —— C24H33N3O6
    ethyl (6R)-4-[(4-ethoxycarbonylpiperidin-1-yl)methyl]-6-(3-methoxyphenyl)-3-methyl-2-oxo-1,6-dihydropyrimidine-5-carboxylate
    —— ethyl (6R)-4-[(4-acetylpiperazin-1-yl)methyl]-6-(3-fluorophenyl)-2-oxo-3-prop-2-enyl-1,6-dihydropyrimidine-5-carboxylate —— C23H29FN4O4
    ethyl (6R)-4-[(4-acetylpiperazin-1-yl)methyl]-6-(3-fluorophenyl)-2-oxo-3-prop-2-enyl-1,6-dihydropyrimidine-5-carboxylate
    —— ethyl (6R)-3-ethyl-6-(2-fluorophenyl)-4-[[(3S)-3-methyl-4-propanoylpiperazin-1-yl]methyl]-2-oxo-1,6-dihydropyrimidine-5-carboxylate —— C24H33FN4O4
    ethyl (6R)-3-ethyl-6-(2-fluorophenyl)-4-[[(3S)-3-methyl-4-propanoylpiperazin-1-yl]methyl]-2-oxo-1,6-dihydropyrimidine-5-carboxylate
    —— ethyl (6R)-3-ethyl-6-(3-methylphenyl)-4-[[(2S)-2-methylpiperidin-1-yl]methyl]-2-oxo-1,6-dihydropyrimidine-5-carboxylate —— C23H33N3O3
    ethyl (6R)-3-ethyl-6-(3-methylphenyl)-4-[[(2S)-2-methylpiperidin-1-yl]methyl]-2-oxo-1,6-dihydropyrimidine-5-carboxylate
    —— ethyl (6S)-4-[[(3S)-3-ethoxycarbonylpiperidin-1-yl]methyl]-6-(3-fluorophenyl)-3-methyl-2-oxo-1,6-dihydropyrimidine-5-carboxylate —— C23H30FN3O5
    ethyl (6S)-4-[[(3S)-3-ethoxycarbonylpiperidin-1-yl]methyl]-6-(3-fluorophenyl)-3-methyl-2-oxo-1,6-dihydropyrimidine-5-carboxylate
    —— ethyl (6R)-6-(2-methoxyphenyl)-3-methyl-2-oxo-4-[(4-propanoyl-1,4-diazepan-1-yl)methyl]-1,6-dihydropyrimidine-5-carboxylate —— C24H34N4O5
    ethyl (6R)-6-(2-methoxyphenyl)-3-methyl-2-oxo-4-[(4-propanoyl-1,4-diazepan-1-yl)methyl]-1,6-dihydropyrimidine-5-carboxylate
    —— ethyl (6R)-6-(3,4-dichlorophenyl)-3-ethyl-2-oxo-4-[(4-propanoyl-1,4-diazepan-1-yl)methyl]-1,6-dihydropyrimidine-5-carboxylate —— C24H32Cl2N4O4
    ethyl (6R)-6-(3,4-dichlorophenyl)-3-ethyl-2-oxo-4-[(4-propanoyl-1,4-diazepan-1-yl)methyl]-1,6-dihydropyrimidine-5-carboxylate
    —— ethyl (6R)-4-[(4-ethoxycarbonylpiperidin-1-yl)methyl]-3-methyl-6-(3-methylphenyl)-2-oxo-1,6-dihydropyrimidine-5-carboxylate —— C24H33N3O5
    ethyl (6R)-4-[(4-ethoxycarbonylpiperidin-1-yl)methyl]-3-methyl-6-(3-methylphenyl)-2-oxo-1,6-dihydropyrimidine-5-carboxylate
    —— ethyl (6S)-3-methyl-2-oxo-4-(piperidin-1-ylmethyl)-6-[2-(trifluoromethyl)phenyl]-1,6-dihydropyrimidine-5-carboxylate —— C21H26F3N3O3
    ethyl (6S)-3-methyl-2-oxo-4-(piperidin-1-ylmethyl)-6-[2-(trifluoromethyl)phenyl]-1,6-dihydropyrimidine-5-carboxylate
    —— ethyl (6R)-4-[[benzyl(methyl)amino]methyl]-6-(3-fluorophenyl)-2-oxo-3-prop-2-enyl-1,6-dihydropyrimidine-5-carboxylate —— C25H28FN3O3
    ethyl (6R)-4-[[benzyl(methyl)amino]methyl]-6-(3-fluorophenyl)-2-oxo-3-prop-2-enyl-1,6-dihydropyrimidine-5-carboxylate
    —— ethyl (6S)-4-[(4-benzylpiperazin-1-yl)methyl]-3-methyl-6-(4-methylphenyl)-2-oxo-1,6-dihydropyrimidine-5-carboxylate —— C27H34N4O3
    ethyl (6S)-4-[(4-benzylpiperazin-1-yl)methyl]-3-methyl-6-(4-methylphenyl)-2-oxo-1,6-dihydropyrimidine-5-carboxylate
    —— ethyl (6R)-3-ethyl-6-(2-fluorophenyl)-4-[[(3R)-3-methyl-4-(3-methylbutanoyl)piperazin-1-yl]methyl]-2-oxo-1,6-dihydropyrimidine-5-carboxylate —— C26H37FN4O4
    ethyl (6R)-3-ethyl-6-(2-fluorophenyl)-4-[[(3R)-3-methyl-4-(3-methylbutanoyl)piperazin-1-yl]methyl]-2-oxo-1,6-dihydropyrimidine-5-carboxylate
    —— ethyl (6R)-2-oxo-4-(piperidin-1-ylmethyl)-3-prop-2-enyl-6-thiophen-3-yl-1,6-dihydropyrimidine-5-carboxylate —— C20H27N3O3S
    ethyl (6R)-2-oxo-4-(piperidin-1-ylmethyl)-3-prop-2-enyl-6-thiophen-3-yl-1,6-dihydropyrimidine-5-carboxylate
    —— ethyl (6S)-6-(2-chlorophenyl)-4-(morpholin-4-ylmethyl)-2-oxo-3-prop-2-enyl-1,6-dihydropyrimidine-5-carboxylate —— C21H26ClN3O4
    ethyl (6S)-6-(2-chlorophenyl)-4-(morpholin-4-ylmethyl)-2-oxo-3-prop-2-enyl-1,6-dihydropyrimidine-5-carboxylate
    —— ethyl (6S)-3-ethyl-6-(3-fluorophenyl)-4-(morpholin-4-ylmethyl)-2-oxo-1,6-dihydropyrimidine-5-carboxylate —— C20H26FN3O4
    ethyl (6S)-3-ethyl-6-(3-fluorophenyl)-4-(morpholin-4-ylmethyl)-2-oxo-1,6-dihydropyrimidine-5-carboxylate
    —— ethyl (6R)-4-[[(3S)-3-ethoxycarbonylpiperidin-1-yl]methyl]-3-ethyl-2-oxo-6-phenyl-1,6-dihydropyrimidine-5-carboxylate —— C24H33N3O5
    ethyl (6R)-4-[[(3S)-3-ethoxycarbonylpiperidin-1-yl]methyl]-3-ethyl-2-oxo-6-phenyl-1,6-dihydropyrimidine-5-carboxylate
    —— ethyl (6S)-4-[(4-acetylpiperazin-1-yl)methyl]-6-(4-methylphenyl)-2-oxo-3-prop-2-enyl-1,6-dihydropyrimidine-5-carboxylate —— C24H32N4O4
    ethyl (6S)-4-[(4-acetylpiperazin-1-yl)methyl]-6-(4-methylphenyl)-2-oxo-3-prop-2-enyl-1,6-dihydropyrimidine-5-carboxylate
    —— ethyl (6R)-4-[(4-benzylpiperazin-1-yl)methyl]-6-(4-methylphenyl)-2-oxo-3-prop-2-enyl-1,6-dihydropyrimidine-5-carboxylate —— C29H36N4O3
    ethyl (6R)-4-[(4-benzylpiperazin-1-yl)methyl]-6-(4-methylphenyl)-2-oxo-3-prop-2-enyl-1,6-dihydropyrimidine-5-carboxylate
    —— ethyl (6S)-4-[[(3S)-3-ethoxycarbonylpiperidin-1-yl]methyl]-3-methyl-2-oxo-6-phenyl-1,6-dihydropyrimidine-5-carboxylate —— C23H31N3O5
    ethyl (6S)-4-[[(3S)-3-ethoxycarbonylpiperidin-1-yl]methyl]-3-methyl-2-oxo-6-phenyl-1,6-dihydropyrimidine-5-carboxylate
    —— ethyl (6S)-4-[[(3S)-3-ethoxycarbonylpiperidin-1-yl]methyl]-6-(4-methylphenyl)-2-oxo-3-prop-2-enyl-1,6-dihydropyrimidine-5-carboxylate —— C26H35N3O5
    ethyl (6S)-4-[[(3S)-3-ethoxycarbonylpiperidin-1-yl]methyl]-6-(4-methylphenyl)-2-oxo-3-prop-2-enyl-1,6-dihydropyrimidine-5-carboxylate
    —— ethyl (6S)-6-(3,5-dimethoxyphenyl)-3-methyl-2-oxo-4-[[4-(thiophene-2-carbonyl)piperazin-1-yl]methyl]-1,6-dihydropyrimidine-5-carboxylate —— C26H32N4O6S
    ethyl (6S)-6-(3,5-dimethoxyphenyl)-3-methyl-2-oxo-4-[[4-(thiophene-2-carbonyl)piperazin-1-yl]methyl]-1,6-dihydropyrimidine-5-carboxylate
    —— ethyl (6S)-4-[[4-(cyclopropanecarbonyl)piperazin-1-yl]methyl]-3-methyl-6-(3-methylphenyl)-2-oxo-1,6-dihydropyrimidine-5-carboxylate —— C24H32N4O4
    ethyl (6S)-4-[[4-(cyclopropanecarbonyl)piperazin-1-yl]methyl]-3-methyl-6-(3-methylphenyl)-2-oxo-1,6-dihydropyrimidine-5-carboxylate
    —— ethyl (6R)-3-ethyl-6-(2-fluorophenyl)-4-[[(3R)-3-methyl-4-propanoylpiperazin-1-yl]methyl]-2-oxo-1,6-dihydropyrimidine-5-carboxylate —— C24H33FN4O4
    ethyl (6R)-3-ethyl-6-(2-fluorophenyl)-4-[[(3R)-3-methyl-4-propanoylpiperazin-1-yl]methyl]-2-oxo-1,6-dihydropyrimidine-5-carboxylate
    —— ethyl (6R)-6-(2,4-dimethylphenyl)-3-methyl-4-(morpholin-4-ylmethyl)-2-oxo-1,6-dihydropyrimidine-5-carboxylate —— C21H29N3O4
    ethyl (6R)-6-(2,4-dimethylphenyl)-3-methyl-4-(morpholin-4-ylmethyl)-2-oxo-1,6-dihydropyrimidine-5-carboxylate
    —— ethyl (6S)-3-ethyl-6-(3-fluorophenyl)-2-oxo-4-(piperidin-1-ylmethyl)-1,6-dihydropyrimidine-5-carboxylate —— C21H28FN3O3
    ethyl (6S)-3-ethyl-6-(3-fluorophenyl)-2-oxo-4-(piperidin-1-ylmethyl)-1,6-dihydropyrimidine-5-carboxylate
    —— ethyl (6S)-6-(4-chlorophenyl)-2-oxo-4-(piperidin-1-ylmethyl)-3-prop-2-enyl-1,6-dihydropyrimidine-5-carboxylate —— C22H28ClN3O3
    ethyl (6S)-6-(4-chlorophenyl)-2-oxo-4-(piperidin-1-ylmethyl)-3-prop-2-enyl-1,6-dihydropyrimidine-5-carboxylate
    —— ethyl (6S)-3-methyl-4-[(4-methylpiperidin-1-yl)methyl]-2-oxo-6-[2-(trifluoromethyl)phenyl]-1,6-dihydropyrimidine-5-carboxylate —— C22H28F3N3O3
    ethyl (6S)-3-methyl-4-[(4-methylpiperidin-1-yl)methyl]-2-oxo-6-[2-(trifluoromethyl)phenyl]-1,6-dihydropyrimidine-5-carboxylate
    —— ethyl (6R)-3-methyl-6-(3-methylphenyl)-2-oxo-4-(piperidin-1-ylmethyl)-1,6-dihydropyrimidine-5-carboxylate —— C21H29N3O3
    ethyl (6R)-3-methyl-6-(3-methylphenyl)-2-oxo-4-(piperidin-1-ylmethyl)-1,6-dihydropyrimidine-5-carboxylate
    —— ethyl (6R)-4-[[cyclohexyl(methyl)amino]methyl]-6-(2,3-dichlorophenyl)-3-ethyl-2-oxo-1,6-dihydropyrimidine-5-carboxylate —— C23H31Cl2N3O3
    ethyl (6R)-4-[[cyclohexyl(methyl)amino]methyl]-6-(2,3-dichlorophenyl)-3-ethyl-2-oxo-1,6-dihydropyrimidine-5-carboxylate
    —— ethyl (6S)-4-[[(3R)-3-ethoxycarbonylpiperidin-1-yl]methyl]-6-(4-fluorophenyl)-3-methyl-2-oxo-1,6-dihydropyrimidine-5-carboxylate —— C23H30FN3O5
    ethyl (6S)-4-[[(3R)-3-ethoxycarbonylpiperidin-1-yl]methyl]-6-(4-fluorophenyl)-3-methyl-2-oxo-1,6-dihydropyrimidine-5-carboxylate
    —— ethyl (6R)-4-[(4-ethylpiperazin-1-yl)methyl]-3-methyl-2-oxo-6-(3-phenoxyphenyl)-1,6-dihydropyrimidine-5-carboxylate —— C27H34N4O4
    ethyl (6R)-4-[(4-ethylpiperazin-1-yl)methyl]-3-methyl-2-oxo-6-(3-phenoxyphenyl)-1,6-dihydropyrimidine-5-carboxylate
    —— ethyl (6R)-4-[(4-benzylpiperazin-1-yl)methyl]-3-methyl-6-(3-methylphenyl)-2-oxo-1,6-dihydropyrimidine-5-carboxylate —— C27H34N4O3
    ethyl (6R)-4-[(4-benzylpiperazin-1-yl)methyl]-3-methyl-6-(3-methylphenyl)-2-oxo-1,6-dihydropyrimidine-5-carboxylate
    —— ethyl (6S)-4-[[cyclohexyl(methyl)amino]methyl]-6-(2,3-dichlorophenyl)-3-ethyl-2-oxo-1,6-dihydropyrimidine-5-carboxylate —— C23H31Cl2N3O3
    ethyl (6S)-4-[[cyclohexyl(methyl)amino]methyl]-6-(2,3-dichlorophenyl)-3-ethyl-2-oxo-1,6-dihydropyrimidine-5-carboxylate
    —— ethyl (6R)-4-[(4-benzylpiperazin-1-yl)methyl]-6-(2,5-dimethylphenyl)-3-methyl-2-oxo-1,6-dihydropyrimidine-5-carboxylate —— C28H36N4O3
    ethyl (6R)-4-[(4-benzylpiperazin-1-yl)methyl]-6-(2,5-dimethylphenyl)-3-methyl-2-oxo-1,6-dihydropyrimidine-5-carboxylate
    —— ethyl (6S)-4-[[benzyl(methyl)amino]methyl]-3-methyl-2-oxo-6-(3-phenoxyphenyl)-1,6-dihydropyrimidine-5-carboxylate —— C29H31N3O4
    ethyl (6S)-4-[[benzyl(methyl)amino]methyl]-3-methyl-2-oxo-6-(3-phenoxyphenyl)-1,6-dihydropyrimidine-5-carboxylate
    —— ethyl (6S)-6-(2-fluorophenyl)-4-[[4-(4-methoxybenzoyl)-1,4-diazepan-1-yl]methyl]-3-methyl-2-oxo-1,6-dihydropyrimidine-5-carboxylate —— C28H33FN4O5
    ethyl (6S)-6-(2-fluorophenyl)-4-[[4-(4-methoxybenzoyl)-1,4-diazepan-1-yl]methyl]-3-methyl-2-oxo-1,6-dihydropyrimidine-5-carboxylate
    —— ethyl (6S)-6-(2,3-dichlorophenyl)-3-methyl-4-[(4-methylpiperazin-1-yl)methyl]-2-oxo-1,6-dihydropyrimidine-5-carboxylate —— C20H26Cl2N4O3
    ethyl (6S)-6-(2,3-dichlorophenyl)-3-methyl-4-[(4-methylpiperazin-1-yl)methyl]-2-oxo-1,6-dihydropyrimidine-5-carboxylate
    —— ethyl (6R)-3-ethyl-6-(3-methoxyphenyl)-4-[[methyl(propyl)amino]methyl]-2-oxo-1,6-dihydropyrimidine-5-carboxylate —— C21H31N3O4
    ethyl (6R)-3-ethyl-6-(3-methoxyphenyl)-4-[[methyl(propyl)amino]methyl]-2-oxo-1,6-dihydropyrimidine-5-carboxylate
    —— ethyl (6R)-6-(2-chlorophenyl)-4-[(4-methylpiperidin-1-yl)methyl]-2-oxo-3-prop-2-enyl-1,6-dihydropyrimidine-5-carboxylate —— C23H30ClN3O3
    ethyl (6R)-6-(2-chlorophenyl)-4-[(4-methylpiperidin-1-yl)methyl]-2-oxo-3-prop-2-enyl-1,6-dihydropyrimidine-5-carboxylate
    —— ethyl (6R)-3-ethyl-6-(3-methylphenyl)-4-[(4-methylpiperazin-1-yl)methyl]-2-oxo-1,6-dihydropyrimidine-5-carboxylate —— C22H32N4O3
    ethyl (6R)-3-ethyl-6-(3-methylphenyl)-4-[(4-methylpiperazin-1-yl)methyl]-2-oxo-1,6-dihydropyrimidine-5-carboxylate
    —— ethyl (6R)-4-[[4-(cyclobutanecarbonyl)-1,4-diazepan-1-yl]methyl]-6-(2-fluorophenyl)-3-methyl-2-oxo-1,6-dihydropyrimidine-5-carboxylate —— C25H33FN4O4
    ethyl (6R)-4-[[4-(cyclobutanecarbonyl)-1,4-diazepan-1-yl]methyl]-6-(2-fluorophenyl)-3-methyl-2-oxo-1,6-dihydropyrimidine-5-carboxylate
    —— ethyl (6R)-4-[(4-benzoyl-1,4-diazepan-1-yl)methyl]-6-(2-methoxyphenyl)-3-methyl-2-oxo-1,6-dihydropyrimidine-5-carboxylate —— C28H34N4O5
    ethyl (6R)-4-[(4-benzoyl-1,4-diazepan-1-yl)methyl]-6-(2-methoxyphenyl)-3-methyl-2-oxo-1,6-dihydropyrimidine-5-carboxylate