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生物碱及其衍生物

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中文名称 英文名称 CAS号 化学式 结构式图片
—— [(1R,5R)-3-(4-fluorophenyl)-8-azabicyclo[3.2.1]octan-8-yl]-[4-(thietan-3-yloxy)phenyl]methanone —— C23H24FNO2S
[(1R,5R)-3-(4-fluorophenyl)-8-azabicyclo[3.2.1]octan-8-yl]-[4-(thietan-3-yloxy)phenyl]methanone
—— [(1S,5S)-3-(4-fluorophenyl)-8-azabicyclo[3.2.1]octan-8-yl]-(1,3-thiazol-4-yl)methanone —— C17H17FN2OS
[(1S,5S)-3-(4-fluorophenyl)-8-azabicyclo[3.2.1]octan-8-yl]-(1,3-thiazol-4-yl)methanone
—— 2-[2-[(1R,5R)-3-(4-fluorophenyl)-8-azabicyclo[3.2.1]octan-8-yl]-2-oxoethyl]-1,1-dioxo-1,2-benzothiazol-3-one —— C22H21FN2O4S
2-[2-[(1R,5R)-3-(4-fluorophenyl)-8-azabicyclo[3.2.1]octan-8-yl]-2-oxoethyl]-1,1-dioxo-1,2-benzothiazol-3-one
—— (3,5-difluorophenyl)-[(1R,5R)-3-(4-fluorophenyl)-8-azabicyclo[3.2.1]octan-8-yl]methanone —— C20H18F3NO
(3,5-difluorophenyl)-[(1R,5R)-3-(4-fluorophenyl)-8-azabicyclo[3.2.1]octan-8-yl]methanone
—— 2,1,3-benzothiadiazol-5-yl-[(1R,5R)-3-(4-fluorophenyl)-8-azabicyclo[3.2.1]octan-8-yl]methanone —— C20H18FN3OS
2,1,3-benzothiadiazol-5-yl-[(1R,5R)-3-(4-fluorophenyl)-8-azabicyclo[3.2.1]octan-8-yl]methanone
—— [(1R,5R)-3-(4-fluorophenyl)-8-azabicyclo[3.2.1]octan-8-yl]-(5-hydroxypyridin-3-yl)methanone —— C19H19FN2O2
[(1R,5R)-3-(4-fluorophenyl)-8-azabicyclo[3.2.1]octan-8-yl]-(5-hydroxypyridin-3-yl)methanone
—— [(1S,5S)-3-(4-fluorophenyl)-8-azabicyclo[3.2.1]octan-8-yl]-pyridin-4-ylmethanone —— C19H19FN2O
[(1S,5S)-3-(4-fluorophenyl)-8-azabicyclo[3.2.1]octan-8-yl]-pyridin-4-ylmethanone
—— 2-[3-[(1S,5S)-3-(4-fluorophenyl)-8-azabicyclo[3.2.1]octan-8-yl]-3-oxopropyl]-1H-pyridazine-3,6-dione —— C20H22FN3O3
2-[3-[(1S,5S)-3-(4-fluorophenyl)-8-azabicyclo[3.2.1]octan-8-yl]-3-oxopropyl]-1H-pyridazine-3,6-dione
—— [(1S,5S)-3-(4-fluorophenyl)-8-azabicyclo[3.2.1]octan-8-yl]-pyridin-2-ylmethanone —— C19H19FN2O
[(1S,5S)-3-(4-fluorophenyl)-8-azabicyclo[3.2.1]octan-8-yl]-pyridin-2-ylmethanone
—— 4-[2-[(1R,5R)-3-(4-fluorophenyl)-8-azabicyclo[3.2.1]octan-8-yl]-2-oxoethyl]-2-propan-2-ylphthalazin-1-one —— C26H28FN3O2
4-[2-[(1R,5R)-3-(4-fluorophenyl)-8-azabicyclo[3.2.1]octan-8-yl]-2-oxoethyl]-2-propan-2-ylphthalazin-1-one
—— [(1S,5S)-3-(4-fluorophenyl)-8-azabicyclo[3.2.1]octan-8-yl]-quinolin-5-ylmethanone —— C23H21FN2O
[(1S,5S)-3-(4-fluorophenyl)-8-azabicyclo[3.2.1]octan-8-yl]-quinolin-5-ylmethanone
—— [(1R,5R)-3-(4-fluorophenyl)-8-azabicyclo[3.2.1]octan-8-yl]-(furan-2-yl)methanone —— C18H18FNO2
[(1R,5R)-3-(4-fluorophenyl)-8-azabicyclo[3.2.1]octan-8-yl]-(furan-2-yl)methanone
—— [(1R,5R)-3-(4-fluorophenyl)-8-azabicyclo[3.2.1]octan-8-yl]-(1-methylsulfonylpiperidin-4-yl)methanone —— C20H27FN2O3S
[(1R,5R)-3-(4-fluorophenyl)-8-azabicyclo[3.2.1]octan-8-yl]-(1-methylsulfonylpiperidin-4-yl)methanone
—— [(1R,5R)-3-(4-fluorophenyl)-8-azabicyclo[3.2.1]octan-8-yl]-isoquinolin-1-ylmethanone —— C23H21FN2O
[(1R,5R)-3-(4-fluorophenyl)-8-azabicyclo[3.2.1]octan-8-yl]-isoquinolin-1-ylmethanone
—— 3-[2-[(1R,5R)-3-(4-fluorophenyl)-8-azabicyclo[3.2.1]octan-8-yl]-2-oxoethyl]quinazolin-4-one —— C23H22FN3O2
3-[2-[(1R,5R)-3-(4-fluorophenyl)-8-azabicyclo[3.2.1]octan-8-yl]-2-oxoethyl]quinazolin-4-one
—— (3S)-3-[2-[(1R,5R)-3-(4-fluorophenyl)-8-azabicyclo[3.2.1]octan-8-yl]-2-oxoethyl]-2,3-dihydroisoindol-1-one —— C23H23FN2O2
(3S)-3-[2-[(1R,5R)-3-(4-fluorophenyl)-8-azabicyclo[3.2.1]octan-8-yl]-2-oxoethyl]-2,3-dihydroisoindol-1-one
—— 4-[(1R,5R)-3-(4-fluorophenyl)-8-azabicyclo[3.2.1]octane-8-carbonyl]-2H-phthalazin-1-one —— C22H20FN3O2
4-[(1R,5R)-3-(4-fluorophenyl)-8-azabicyclo[3.2.1]octane-8-carbonyl]-2H-phthalazin-1-one
—— [(1R,5R)-3-(4-fluorophenyl)-8-azabicyclo[3.2.1]octan-8-yl]-pyridin-3-ylmethanone —— C19H19FN2O
[(1R,5R)-3-(4-fluorophenyl)-8-azabicyclo[3.2.1]octan-8-yl]-pyridin-3-ylmethanone
—— [(1R,5R)-3-(4-fluorophenyl)-8-azabicyclo[3.2.1]octan-8-yl]-(4-methylthiadiazol-5-yl)methanone —— C17H18FN3OS
[(1R,5R)-3-(4-fluorophenyl)-8-azabicyclo[3.2.1]octan-8-yl]-(4-methylthiadiazol-5-yl)methanone
—— [(1R,5R)-3-(4-fluorophenyl)-8-azabicyclo[3.2.1]octan-8-yl]-thiophen-2-ylmethanone —— C18H18FNOS
[(1R,5R)-3-(4-fluorophenyl)-8-azabicyclo[3.2.1]octan-8-yl]-thiophen-2-ylmethanone
—— 4-[(2S)-1-[(1R,5R)-3-(4-fluorophenyl)-8-azabicyclo[3.2.1]octan-8-yl]-1-oxopropan-2-yl]-2H-phthalazin-1-one —— C24H24FN3O2
4-[(2S)-1-[(1R,5R)-3-(4-fluorophenyl)-8-azabicyclo[3.2.1]octan-8-yl]-1-oxopropan-2-yl]-2H-phthalazin-1-one
—— [(1S,5S)-3-(4-fluorophenyl)-8-azabicyclo[3.2.1]octan-8-yl]-pyrazolo[1,5-a]pyrimidin-3-ylmethanone —— C20H19FN4O
[(1S,5S)-3-(4-fluorophenyl)-8-azabicyclo[3.2.1]octan-8-yl]-pyrazolo[1,5-a]pyrimidin-3-ylmethanone
—— 2-[2-[(1R,5R)-3-(4-fluorophenyl)-8-azabicyclo[3.2.1]octan-8-yl]-2-oxoethyl]-5-methyl-1H-[1,2,4]triazolo[1,5-a]pyrimidin-7-one —— C21H22FN5O2
2-[2-[(1R,5R)-3-(4-fluorophenyl)-8-azabicyclo[3.2.1]octan-8-yl]-2-oxoethyl]-5-methyl-1H-[1,2,4]triazolo[1,5-a]pyrimidin-7-one
—— 2-[3-[(1R,5R)-3-(4-fluorophenyl)-8-azabicyclo[3.2.1]octan-8-yl]-3-oxopropyl]-1H-pyridazine-3,6-dione —— C20H22FN3O3
2-[3-[(1R,5R)-3-(4-fluorophenyl)-8-azabicyclo[3.2.1]octan-8-yl]-3-oxopropyl]-1H-pyridazine-3,6-dione
—— [(1R,5R)-3-(4-fluorophenyl)-8-azabicyclo[3.2.1]octan-8-yl]-pyrazolo[1,5-a]pyrimidin-3-ylmethanone —— C20H19FN4O
[(1R,5R)-3-(4-fluorophenyl)-8-azabicyclo[3.2.1]octan-8-yl]-pyrazolo[1,5-a]pyrimidin-3-ylmethanone
—— [(1S,5S)-3-(4-fluorophenyl)-8-azabicyclo[3.2.1]octan-8-yl]-[3-(tetrazol-1-yl)phenyl]methanone —— C21H20FN5O
[(1S,5S)-3-(4-fluorophenyl)-8-azabicyclo[3.2.1]octan-8-yl]-[3-(tetrazol-1-yl)phenyl]methanone
—— 2-ethyl-4-[2-[(1S,5S)-3-(4-fluorophenyl)-8-azabicyclo[3.2.1]octan-8-yl]-2-oxoethyl]phthalazin-1-one —— C25H26FN3O2
2-ethyl-4-[2-[(1S,5S)-3-(4-fluorophenyl)-8-azabicyclo[3.2.1]octan-8-yl]-2-oxoethyl]phthalazin-1-one
—— 3-[3-[(1R,5R)-3-(4-fluorophenyl)-8-azabicyclo[3.2.1]octan-8-yl]-3-oxopropyl]-1,3-benzoxazol-2-one —— C23H23FN2O3
3-[3-[(1R,5R)-3-(4-fluorophenyl)-8-azabicyclo[3.2.1]octan-8-yl]-3-oxopropyl]-1,3-benzoxazol-2-one
—— [(1S,5S)-3-(4-fluorophenyl)-8-azabicyclo[3.2.1]octan-8-yl]-(4-methyl-1,3-thiazol-5-yl)methanone —— C18H19FN2OS
[(1S,5S)-3-(4-fluorophenyl)-8-azabicyclo[3.2.1]octan-8-yl]-(4-methyl-1,3-thiazol-5-yl)methanone
—— 1-[(1R,5R)-3-(4-fluorophenyl)-8-azabicyclo[3.2.1]octan-8-yl]-2-[4-(tetrazol-1-yl)phenyl]ethanone —— C22H22FN5O
1-[(1R,5R)-3-(4-fluorophenyl)-8-azabicyclo[3.2.1]octan-8-yl]-2-[4-(tetrazol-1-yl)phenyl]ethanone
—— (4-amino-5-chloro-2-methoxyphenyl)-[(1S,5S)-3-(4-fluorophenyl)-8-azabicyclo[3.2.1]octan-8-yl]methanone —— C21H22ClFN2O2
(4-amino-5-chloro-2-methoxyphenyl)-[(1S,5S)-3-(4-fluorophenyl)-8-azabicyclo[3.2.1]octan-8-yl]methanone
—— 3-[3-[(1S,5S)-3-(4-fluorophenyl)-8-azabicyclo[3.2.1]octan-8-yl]-3-oxopropyl]-1,3-benzoxazol-2-one —— C23H23FN2O3
3-[3-[(1S,5S)-3-(4-fluorophenyl)-8-azabicyclo[3.2.1]octan-8-yl]-3-oxopropyl]-1,3-benzoxazol-2-one
—— (4-amino-5-chloro-2-methoxyphenyl)-[(1R,5R)-3-(4-fluorophenyl)-8-azabicyclo[3.2.1]octan-8-yl]methanone —— C21H22ClFN2O2
(4-amino-5-chloro-2-methoxyphenyl)-[(1R,5R)-3-(4-fluorophenyl)-8-azabicyclo[3.2.1]octan-8-yl]methanone
—— (2-fluorophenyl)-[(1S,5S)-3-(4-fluorophenyl)-8-azabicyclo[3.2.1]octan-8-yl]methanone —— C20H19F2NO
(2-fluorophenyl)-[(1S,5S)-3-(4-fluorophenyl)-8-azabicyclo[3.2.1]octan-8-yl]methanone
—— 4-[2-[(1S,5S)-3-(4-fluorophenyl)-8-azabicyclo[3.2.1]octan-8-yl]-2-oxoethyl]-2H-phthalazin-1-one —— C23H22FN3O2
4-[2-[(1S,5S)-3-(4-fluorophenyl)-8-azabicyclo[3.2.1]octan-8-yl]-2-oxoethyl]-2H-phthalazin-1-one
—— 2-(3,4-dimethoxyphenyl)-1-[(1S,5S)-3-(4-fluorophenyl)-8-azabicyclo[3.2.1]octan-8-yl]ethanone —— C23H26FNO3
2-(3,4-dimethoxyphenyl)-1-[(1S,5S)-3-(4-fluorophenyl)-8-azabicyclo[3.2.1]octan-8-yl]ethanone
—— (3,5-dimethyl-1,2-oxazol-4-yl)-[(1R,5R)-3-(4-fluorophenyl)-8-azabicyclo[3.2.1]octan-8-yl]methanone —— C19H21FN2O2
(3,5-dimethyl-1,2-oxazol-4-yl)-[(1R,5R)-3-(4-fluorophenyl)-8-azabicyclo[3.2.1]octan-8-yl]methanone
—— (4R)-4-[(1R,5R)-3-(4-fluorophenyl)-8-azabicyclo[3.2.1]octane-8-carbonyl]-1-methylpyrrolidin-2-one —— C19H23FN2O2
(4R)-4-[(1R,5R)-3-(4-fluorophenyl)-8-azabicyclo[3.2.1]octane-8-carbonyl]-1-methylpyrrolidin-2-one
—— 2-[3-[(1S,5S)-3-(4-fluorophenyl)-8-azabicyclo[3.2.1]octan-8-yl]-3-oxopropyl]-1,1-dioxo-1,2-benzothiazol-3-one —— C23H23FN2O4S
2-[3-[(1S,5S)-3-(4-fluorophenyl)-8-azabicyclo[3.2.1]octan-8-yl]-3-oxopropyl]-1,1-dioxo-1,2-benzothiazol-3-one
—— 2-(benzotriazol-1-yl)-1-[(1R,5R)-3-(4-fluorophenyl)-8-azabicyclo[3.2.1]octan-8-yl]ethanone —— C21H21FN4O
2-(benzotriazol-1-yl)-1-[(1R,5R)-3-(4-fluorophenyl)-8-azabicyclo[3.2.1]octan-8-yl]ethanone
—— 4-[2-[(1S,5S)-3-(4-fluorophenyl)-8-azabicyclo[3.2.1]octan-8-yl]-2-oxoethyl]-2-propan-2-ylphthalazin-1-one —— C26H28FN3O2
4-[2-[(1S,5S)-3-(4-fluorophenyl)-8-azabicyclo[3.2.1]octan-8-yl]-2-oxoethyl]-2-propan-2-ylphthalazin-1-one
—— (4S)-4-[(1R,5R)-3-(4-fluorophenyl)-8-azabicyclo[3.2.1]octane-8-carbonyl]-1-methylpyrrolidin-2-one —— C19H23FN2O2
(4S)-4-[(1R,5R)-3-(4-fluorophenyl)-8-azabicyclo[3.2.1]octane-8-carbonyl]-1-methylpyrrolidin-2-one
—— 2-(4,6-dimethylpyrimidin-2-yl)sulfanyl-1-[(1R,5R)-3-(4-fluorophenyl)-8-azabicyclo[3.2.1]octan-8-yl]ethanone —— C21H24FN3OS
2-(4,6-dimethylpyrimidin-2-yl)sulfanyl-1-[(1R,5R)-3-(4-fluorophenyl)-8-azabicyclo[3.2.1]octan-8-yl]ethanone
—— 2,1,3-benzothiadiazol-5-yl-[(1S,5S)-3-(4-fluorophenyl)-8-azabicyclo[3.2.1]octan-8-yl]methanone —— C20H18FN3OS
2,1,3-benzothiadiazol-5-yl-[(1S,5S)-3-(4-fluorophenyl)-8-azabicyclo[3.2.1]octan-8-yl]methanone
—— 1-(2,3-dihydroindol-1-yl)-5-[(1R,5R)-3-(4-fluorophenyl)-8-azabicyclo[3.2.1]octan-8-yl]pentane-1,5-dione —— C26H29FN2O2
1-(2,3-dihydroindol-1-yl)-5-[(1R,5R)-3-(4-fluorophenyl)-8-azabicyclo[3.2.1]octan-8-yl]pentane-1,5-dione
—— 2-[(2R)-1-[(1R,5R)-3-(4-fluorophenyl)-8-azabicyclo[3.2.1]octan-8-yl]-1-oxopropan-2-yl]phthalazin-1-one —— C24H24FN3O2
2-[(2R)-1-[(1R,5R)-3-(4-fluorophenyl)-8-azabicyclo[3.2.1]octan-8-yl]-1-oxopropan-2-yl]phthalazin-1-one
—— [7-(difluoromethyl)-5-methyl-[1,2,4]triazolo[1,5-a]pyrimidin-2-yl]-[(1R,5R)-3-(4-fluorophenyl)-8-azabicyclo[3.2.1]octan-8-yl]methanone —— C21H20F3N5O
[7-(difluoromethyl)-5-methyl-[1,2,4]triazolo[1,5-a]pyrimidin-2-yl]-[(1R,5R)-3-(4-fluorophenyl)-8-azabicyclo[3.2.1]octan-8-yl]methanone
—— 5-[(1S,5S)-3-(4-fluorophenyl)-8-azabicyclo[3.2.1]octane-8-carbonyl]-1,3-dimethylbenzimidazol-2-one —— C23H24FN3O2
5-[(1S,5S)-3-(4-fluorophenyl)-8-azabicyclo[3.2.1]octane-8-carbonyl]-1,3-dimethylbenzimidazol-2-one
—— 2-[2-[(1S,5S)-3-(4-fluorophenyl)-8-azabicyclo[3.2.1]octan-8-yl]-2-oxoethyl]phthalazin-1-one —— C23H22FN3O2
2-[2-[(1S,5S)-3-(4-fluorophenyl)-8-azabicyclo[3.2.1]octan-8-yl]-2-oxoethyl]phthalazin-1-one
—— (1R,9S)-11-bis(4-fluorophenoxy)phosphoryl-7,11-diazatricyclo[7.3.1.02,7]trideca-2,4-dien-6-one —— C23H21F2N2O4P
(1R,9S)-11-bis(4-fluorophenoxy)phosphoryl-7,11-diazatricyclo[7.3.1.02,7]trideca-2,4-dien-6-one