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    首页 分子通 按分子结构分类 有机化合物 有机杂环化合物 咪唑并嘧啶类

    咪唑并嘧啶类

    中文名称 英文名称 CAS号 化学式 结构式图片
    —— 8-(1-ethyl-5-methyl-1H-pyrazol-4-yl)-9-methyl-6-({(3S)-1-[(5-methylisoxazol-4-yl)carbonyl]pyrrolidin-3-yl}oxy)-9H-purine —— C21H24N8O3
    8-(1-ethyl-5-methyl-1H-pyrazol-4-yl)-9-methyl-6-({(3S)-1-[(5-methylisoxazol-4-yl)carbonyl]pyrrolidin-3-yl}oxy)-9H-purine
    —— 8-(1-ethyl-5-methylpyrazol-4-yl)-9-methyl-6-[(3S)-1-pyridin-2-ylpyrrolidin-3-yl]oxypurine —— C21H24N8O
    8-(1-ethyl-5-methylpyrazol-4-yl)-9-methyl-6-[(3S)-1-pyridin-2-ylpyrrolidin-3-yl]oxypurine
    —— 9-ethyl-6-({(3S)-1-[(3-methoxy-3-methylazetidin-1-yl)carbonyl]pyrrolidin-3-yl}oxy)-8-(2-methylpyrimidin-5-yl)-9H-purine —— C22H28N8O3
    9-ethyl-6-({(3S)-1-[(3-methoxy-3-methylazetidin-1-yl)carbonyl]pyrrolidin-3-yl}oxy)-8-(2-methylpyrimidin-5-yl)-9H-purine
    —— 8-(1-ethyl-5-methyl-1H-pyrazol-4-yl)-9-methyl-6-({(3S)-1-[(5-methyl-1,2,3-thiadiazol-4-yl)carbonyl]pyrrolidin-3-yl}oxy)-9H-purine —— C20H23N9O2S
    8-(1-ethyl-5-methyl-1H-pyrazol-4-yl)-9-methyl-6-({(3S)-1-[(5-methyl-1,2,3-thiadiazol-4-yl)carbonyl]pyrrolidin-3-yl}oxy)-9H-purine
    —— tert-butyl (3S)-3-[8-(2-tert-butyl-1,3-thiazol-5-yl)-9-methylpurin-6-yl]oxypyrrolidine-1-carboxylate —— C22H30N6O3S
    tert-butyl (3S)-3-[8-(2-tert-butyl-1,3-thiazol-5-yl)-9-methylpurin-6-yl]oxypyrrolidine-1-carboxylate
    —— [(3S)-3-[8-(1-ethyl-5-methylpyrazol-4-yl)-9-methylpurin-6-yl]oxypyrrolidin-1-yl]-(4-methyloxan-4-yl)methanone —— C23H31N7O3
    [(3S)-3-[8-(1-ethyl-5-methylpyrazol-4-yl)-9-methylpurin-6-yl]oxypyrrolidin-1-yl]-(4-methyloxan-4-yl)methanone
    —— (1-{[(3S)-3-{[9-ethyl-8-(2-methylpyrimidin-5-yl)-9H-purin-6-yl]oxy}pyrrolidin-1-yl]carbonyl}pyrrolidin-3-yl)methanol —— C22H28N8O3
    (1-{[(3S)-3-{[9-ethyl-8-(2-methylpyrimidin-5-yl)-9H-purin-6-yl]oxy}pyrrolidin-1-yl]carbonyl}pyrrolidin-3-yl)methanol
    —— (4-((8-(1-ethyl-5-methyl-1H-pyrazol-4-yl)-9-methyl-9H-purin-6-yl)oxy)piperidin-1-yl)(tetrahydro-2H-pyran-4-yl)methanone —— C23H31N7O3
    (4-((8-(1-ethyl-5-methyl-1H-pyrazol-4-yl)-9-methyl-9H-purin-6-yl)oxy)piperidin-1-yl)(tetrahydro-2H-pyran-4-yl)methanone
    —— 8-(1-ethyl-5-methyl-1H-pyrazol-4-yl)-9-methyl-6-{[(3S)-1-{[1-(1-methylethyl)-1H-pyrazol-5-yl]carbonyl}pyrrolidin-3-yl]oxy}-9H-purine —— C23H29N9O2
    8-(1-ethyl-5-methyl-1H-pyrazol-4-yl)-9-methyl-6-{[(3S)-1-{[1-(1-methylethyl)-1H-pyrazol-5-yl]carbonyl}pyrrolidin-3-yl]oxy}-9H-purine
    —— N-(cis-4-{[9-ethyl-8-(2-methylpyrimidin-5-yl)-9H-purin-6-yl]oxy}cyclohexyl)cyclopropane carboxamide —— C22H27N7O2
    N-(cis-4-{[9-ethyl-8-(2-methylpyrimidin-5-yl)-9H-purin-6-yl]oxy}cyclohexyl)cyclopropane carboxamide
    —— 8-(1-ethyl-5-methyl-1H-pyrazol-4-yl)-6-{[(3S)-1-(isoxazol-5-ylcarbonyl)pyrrolidin-3-yl]oxy}-9-methyl-9H-purine —— C20H22N8O3
    8-(1-ethyl-5-methyl-1H-pyrazol-4-yl)-6-{[(3S)-1-(isoxazol-5-ylcarbonyl)pyrrolidin-3-yl]oxy}-9-methyl-9H-purine
    —— 4-[(3S)-3-[8-(1-ethyl-5-methylpyrazol-4-yl)-9-methylpurin-6-yl]oxypyrrolidin-1-yl]thieno[3,2-d]pyrimidine —— C22H23N9OS
    4-[(3S)-3-[8-(1-ethyl-5-methylpyrazol-4-yl)-9-methylpurin-6-yl]oxypyrrolidin-1-yl]thieno[3,2-d]pyrimidine
    —— 8-(1-ethyl-5-methyl-1H-pyrazol-4-yl)-9-methyl-6-{[(3S)-1-(1,2,5-oxadiazol-3-ylcarbonyl)pyrrolidin-3-yl]oxy}-9H-purine —— C19H21N9O3
    8-(1-ethyl-5-methyl-1H-pyrazol-4-yl)-9-methyl-6-{[(3S)-1-(1,2,5-oxadiazol-3-ylcarbonyl)pyrrolidin-3-yl]oxy}-9H-purine
    —— 8-(1-ethyl-5-methyl-1H-pyrazol-4-yl)-9-methyl-6-{[(3S)-1-{[3-(trifluoromethyl)-1H-pyrazol-4-yl]carbonyl}pyrrolidin-3-yl]oxy}-9H-purine —— C21H22F3N9O2
    8-(1-ethyl-5-methyl-1H-pyrazol-4-yl)-9-methyl-6-{[(3S)-1-{[3-(trifluoromethyl)-1H-pyrazol-4-yl]carbonyl}pyrrolidin-3-yl]oxy}-9H-purine
    —— 8-(1-ethyl-5-methyl-1H-pyrazol-4-yl)-9-methyl-6-{[(3S)-1-{[3-(1-methylethyl)-1H-pyrazol-5-yl]carbonyl}pyrrolidin-3-yl]oxy}-9H-purine —— C23H29N9O2
    8-(1-ethyl-5-methyl-1H-pyrazol-4-yl)-9-methyl-6-{[(3S)-1-{[3-(1-methylethyl)-1H-pyrazol-5-yl]carbonyl}pyrrolidin-3-yl]oxy}-9H-purine
    —— 4-{[(3S)-3-{[8-(1-ethyl-5-methyl-1H-pyrazol-4-yl)-9-methyl-9H-purin-6-yl]oxy}pyrrolidin-1-yl]carbonyl}-1-(1-methylethyl)pyrrolidin-2-one —— C24H32N8O3
    4-{[(3S)-3-{[8-(1-ethyl-5-methyl-1H-pyrazol-4-yl)-9-methyl-9H-purin-6-yl]oxy}pyrrolidin-1-yl]carbonyl}-1-(1-methylethyl)pyrrolidin-2-one
    —— 8-(1-ethyl-5-methyl-1H-pyrazol-4-yl)-9-methyl-6-({(3S)-1-[(2-methyl-1,3-oxazol-4-yl)carbonyl]pyrrolidin-3-yl}oxy)-9H-purine 1610715-48-4 C21H24N8O3
    8-(1-ethyl-5-methyl-1H-pyrazol-4-yl)-9-methyl-6-({(3S)-1-[(2-methyl-1,3-oxazol-4-yl)carbonyl]pyrrolidin-3-yl}oxy)-9H-purine
    —— tert-butyl (3S)-3-[9-methyl-8-(6-morpholin-4-ylpyridin-3-yl)purin-6-yl]oxypyrrolidine-1-carboxylate —— C24H31N7O4
    tert-butyl (3S)-3-[9-methyl-8-(6-morpholin-4-ylpyridin-3-yl)purin-6-yl]oxypyrrolidine-1-carboxylate
    —— 8-(1-ethyl-5-methyl-1H-pyrazol-4-yl)-9-methyl-6-{[(3S)-1-(1H-pyrazol-5-ylcarbonyl)pyrrolidin-3-yl]oxy}-9H-purine —— C20H23N9O2
    8-(1-ethyl-5-methyl-1H-pyrazol-4-yl)-9-methyl-6-{[(3S)-1-(1H-pyrazol-5-ylcarbonyl)pyrrolidin-3-yl]oxy}-9H-purine
    —— tert-butyl (3S)-3-({9-ethyl-8-[methyl(2-methylpropyl)amino]-9H-purin-6-yl}oxy)pyrrolidine-1-carboxylate —— C21H34N6O3
    tert-butyl (3S)-3-({9-ethyl-8-[methyl(2-methylpropyl)amino]-9H-purin-6-yl}oxy)pyrrolidine-1-carboxylate
    —— 8-(1-ethyl-5-methyl-1H-pyrazol-4-yl)-9-methyl-6-{[(3S)-1-(5,6,7,8-tetrahydro[1,2,4]triazolo[4,3-a]pyridin-3-ylcarbonyl)pyrrolidin-3-yl]oxy}-9H-purine —— C23H28N10O2
    8-(1-ethyl-5-methyl-1H-pyrazol-4-yl)-9-methyl-6-{[(3S)-1-(5,6,7,8-tetrahydro[1,2,4]triazolo[4,3-a]pyridin-3-ylcarbonyl)pyrrolidin-3-yl]oxy}-9H-purine
    —— tert-butyl (trans-3-{[9-ethyl-8-(2-methylpyrimidin-5-yl)-9H-purin-6-yl]oxy}cyclobutyl)carbamate —— C21H27N7O3
    tert-butyl (trans-3-{[9-ethyl-8-(2-methylpyrimidin-5-yl)-9H-purin-6-yl]oxy}cyclobutyl)carbamate
    —— 8-(1-ethyl-5-methylpyrazol-4-yl)-9-methyl-6-[(3S)-1-(1-phenylethyl)pyrrolidin-3-yl]oxypurine —— C24H29N7O
    8-(1-ethyl-5-methylpyrazol-4-yl)-9-methyl-6-[(3S)-1-(1-phenylethyl)pyrrolidin-3-yl]oxypurine
    —— 9-methyl-6-{[(3S)-1-propanoylpyrrolidin-3-yl]oxy}-8-(4,5,6,7-tetrahydropyrazolo[1,5-a]pyridin-3-yl)-9H-purine —— C20H25N7O2
    9-methyl-6-{[(3S)-1-propanoylpyrrolidin-3-yl]oxy}-8-(4,5,6,7-tetrahydropyrazolo[1,5-a]pyridin-3-yl)-9H-purine
    —— 8-(1-ethyl-5-methyl-1H-pyrazol-4-yl)-6-{[(3S)-1-(imidazo[1,2-a]pyrimidin-2-ylcarbonyl)pyrrolidin-3-yl]oxy}-9-methyl-9H-purine —— C23H24N10O2
    8-(1-ethyl-5-methyl-1H-pyrazol-4-yl)-6-{[(3S)-1-(imidazo[1,2-a]pyrimidin-2-ylcarbonyl)pyrrolidin-3-yl]oxy}-9-methyl-9H-purine
    —— (3S)-N-cyclohexyl-3-{[8-(1-ethyl-5-methyl-1H-pyrazol-4-yl)-9-methyl-9H-purin-6-yl]oxy}pyrrolidine-1-carboxamide —— C23H32N8O2
    (3S)-N-cyclohexyl-3-{[8-(1-ethyl-5-methyl-1H-pyrazol-4-yl)-9-methyl-9H-purin-6-yl]oxy}pyrrolidine-1-carboxamide
    —— 8-cyclopropyl-9-methyl-6-{[(3S)-1-propanoylpyrrolidin-3-yl]oxy}-9H-purine —— C16H21N5O2
    8-cyclopropyl-9-methyl-6-{[(3S)-1-propanoylpyrrolidin-3-yl]oxy}-9H-purine
    —— 6-{[(3S)-1-(6,7-dihydro-5H-pyrrolo[1,2-d]tetrazol-5-ylcarbonyl)pyrrolidin-3-yl]oxy}-8-(1-ethyl-5-methyl-1H-pyrazol-4-yl)-9-methyl-9H-purine (non-preferred name) —— C21H25N11O2
    6-{[(3S)-1-(6,7-dihydro-5H-pyrrolo[1,2-d]tetrazol-5-ylcarbonyl)pyrrolidin-3-yl]oxy}-8-(1-ethyl-5-methyl-1H-pyrazol-4-yl)-9-methyl-9H-purine (non-preferred name)
    —— N-[3-[8-(1-ethyl-5-methylpyrazol-4-yl)-9-methylpurin-6-yl]oxycyclopentyl]-2-nitropyridin-3-amine —— C22H25N9O3
    N-[3-[8-(1-ethyl-5-methylpyrazol-4-yl)-9-methylpurin-6-yl]oxycyclopentyl]-2-nitropyridin-3-amine
    —— 8-(1-ethyl-5-methylpyrazol-4-yl)-9-methyl-6-[(3S)-1-(1H-pyrrol-2-ylmethyl)pyrrolidin-3-yl]oxypurine —— C21H26N8O
    8-(1-ethyl-5-methylpyrazol-4-yl)-9-methyl-6-[(3S)-1-(1H-pyrrol-2-ylmethyl)pyrrolidin-3-yl]oxypurine
    —— 4-[(3S)-3-[8-(1-ethyl-5-methylpyrazol-4-yl)-9-methylpurin-6-yl]oxypyrrolidin-1-yl]thieno[3,2-c]pyridine —— C23H24N8OS
    4-[(3S)-3-[8-(1-ethyl-5-methylpyrazol-4-yl)-9-methylpurin-6-yl]oxypyrrolidin-1-yl]thieno[3,2-c]pyridine
    —— 1-[(3S)-3-[8-(6-methoxy-5-methylpyridin-3-yl)-9-methylpurin-6-yl]oxypyrrolidin-1-yl]propan-1-one —— C20H24N6O3
    1-[(3S)-3-[8-(6-methoxy-5-methylpyridin-3-yl)-9-methylpurin-6-yl]oxypyrrolidin-1-yl]propan-1-one
    —— 1-[(3S)-3-[8-(1-ethyl-5-methylpyrazol-4-yl)-9-methylpurin-6-yl]oxypyrrolidin-1-yl]phthalazine —— C24H25N9O
    1-[(3S)-3-[8-(1-ethyl-5-methylpyrazol-4-yl)-9-methylpurin-6-yl]oxypyrrolidin-1-yl]phthalazine
    —— 9-ethyl-6-({(3S)-1-[([(1R,2S) or (1R,2R) or (1S,2R) or (1S,2S)]-methylcyclobutyl)carbonyl] pyrrolidin-3-yl}oxy)-8-(2-methylpyrimidin-5-yl)-9H-purine —— C22H27N7O2
    9-ethyl-6-({(3S)-1-[([(1R,2S) or (1R,2R) or (1S,2R) or (1S,2S)]-methylcyclobutyl)carbonyl] pyrrolidin-3-yl}oxy)-8-(2-methylpyrimidin-5-yl)-9H-purine
    —— tert-butyl (3S)-3-({9-ethyl-8-[(2,2,2-trifluoroethyl)carbamoyl]-9H-purin-6-yl}oxy)pyrrolidine-1-carboxylate —— C19H25F3N6O4
    tert-butyl (3S)-3-({9-ethyl-8-[(2,2,2-trifluoroethyl)carbamoyl]-9H-purin-6-yl}oxy)pyrrolidine-1-carboxylate
    —— 3-(dimethylamino)propyl (3S)-3-{[9-ethyl-8-(2-methylpyrimidin-5-yl)-9H-purin-6-yl]oxy}pyrrolidine-1-carboxylate —— C22H30N8O3
    3-(dimethylamino)propyl (3S)-3-{[9-ethyl-8-(2-methylpyrimidin-5-yl)-9H-purin-6-yl]oxy}pyrrolidine-1-carboxylate
    —— 8-(1-ethyl-5-methyl-1H-pyrazol-4-yl)-9-methyl-6-({(3S)-1-[(6-methylpyridin-3-yl)carbonyl]pyrrolidin-3-yl}oxy)-9H-purine —— C23H26N8O2
    8-(1-ethyl-5-methyl-1H-pyrazol-4-yl)-9-methyl-6-({(3S)-1-[(6-methylpyridin-3-yl)carbonyl]pyrrolidin-3-yl}oxy)-9H-purine
    —— 1-[(3S)-3-[8-(2-tert-butyl-1,3-thiazol-5-yl)-9-methylpurin-6-yl]oxypyrrolidin-1-yl]propan-1-one —— C20H26N6O2S
    1-[(3S)-3-[8-(2-tert-butyl-1,3-thiazol-5-yl)-9-methylpurin-6-yl]oxypyrrolidin-1-yl]propan-1-one
    —— 9-ethyl-8-(2-methylpyrimidin-5-yl)-6-{[(3S)-1-(tetrahydro-2H-pyran-4-ylcarbonyl)pyrrolidin-3-yl]oxy}-9H-purine —— C22H27N7O3
    9-ethyl-8-(2-methylpyrimidin-5-yl)-6-{[(3S)-1-(tetrahydro-2H-pyran-4-ylcarbonyl)pyrrolidin-3-yl]oxy}-9H-purine
    —— 8-(1-ethyl-5-methyl-1H-pyrazol-4-yl)-9-methyl-6-({(3S)-1-[(3-methylisoxazol-4-yl)carbonyl]pyrrolidin-3-yl}oxy)-9H-purine —— C21H24N8O3
    8-(1-ethyl-5-methyl-1H-pyrazol-4-yl)-9-methyl-6-({(3S)-1-[(3-methylisoxazol-4-yl)carbonyl]pyrrolidin-3-yl}oxy)-9H-purine
    —— 6-({(3S)-1-[(2S,3S)-(2,3-dimethylcyclopropyl)carbonyl] pyrrolidin-3-yl}oxy)-9-ethyl-8-(2-methylpyrimidin-5-yl)-9H-purine —— C22H27N7O2
    6-({(3S)-1-[(2S,3S)-(2,3-dimethylcyclopropyl)carbonyl] pyrrolidin-3-yl}oxy)-9-ethyl-8-(2-methylpyrimidin-5-yl)-9H-purine
    —— 2-(5-{[(3S)-3-{[8-(1-ethyl-5 methyl-1H-pyrazol-4-yl)-9-methyl-9H-purin-6-yl]oxy}pyrrolidin-1-yl]carbonyl}-1,2,4-oxadiazol-yl)propan-2-ol —— C22H27N9O4
    2-(5-{[(3S)-3-{[8-(1-ethyl-5 methyl-1H-pyrazol-4-yl)-9-methyl-9H-purin-6-yl]oxy}pyrrolidin-1-yl]carbonyl}-1,2,4-oxadiazol-yl)propan-2-ol
    —— cis-tert-butyl [(1S,3R)-3-{[8-(1-ethyl-5-methyl-1H-pyrazol-4-yl)-9-methyl-9H-purin-6-yl]oxy}cyclopentyl]carbamate —— C22H31N7O3
    cis-tert-butyl [(1S,3R)-3-{[8-(1-ethyl-5-methyl-1H-pyrazol-4-yl)-9-methyl-9H-purin-6-yl]oxy}cyclopentyl]carbamate
    —— 1-[(3S)-3-[8-(2-tert-butyl-1,3-thiazol-5-yl)-9-ethylpurin-6-yl]oxypyrrolidin-1-yl]propan-1-one —— C21H28N6O2S
    1-[(3S)-3-[8-(2-tert-butyl-1,3-thiazol-5-yl)-9-ethylpurin-6-yl]oxypyrrolidin-1-yl]propan-1-one
    —— 8-(1-ethyl-5-methyl-1H-pyrazol-4-yl)-9-methyl-6-({(3S)-1-[(1-methyl-1H-1,2,3-triazol-4-yl)carbonyl]pyrrolidin-3-yl}oxy)-9H-purine —— C20H24N10O2
    8-(1-ethyl-5-methyl-1H-pyrazol-4-yl)-9-methyl-6-({(3S)-1-[(1-methyl-1H-1,2,3-triazol-4-yl)carbonyl]pyrrolidin-3-yl}oxy)-9H-purine
    —— tert-butyl 3-[[9-ethyl-8-(2-methyl-2H-pyrimidin-5-ylidene)-7H-purin-6-yl]oxy]-4-fluoropyrrolidine-1-carboxylate —— C21H28FN7O3
    tert-butyl 3-[[9-ethyl-8-(2-methyl-2H-pyrimidin-5-ylidene)-7H-purin-6-yl]oxy]-4-fluoropyrrolidine-1-carboxylate
    —— cyclopropyl-[(3S,4R)-3-[9-ethyl-8-(2-methylpyrimidin-5-yl)purin-6-yl]oxy-4-(fluoromethyl)pyrrolidin-1-yl]methanone —— C21H24FN7O2
    cyclopropyl-[(3S,4R)-3-[9-ethyl-8-(2-methylpyrimidin-5-yl)purin-6-yl]oxy-4-(fluoromethyl)pyrrolidin-1-yl]methanone
    —— [(4R)-1-azabicyclo[2.2.1]heptan-3-yl]-[(3S)-3-[9-ethyl-8-(2-methylpyrimidin-5-yl)purin-6-yl]oxypyrrolidin-1-yl]methanone —— C23H28N8O2
    [(4R)-1-azabicyclo[2.2.1]heptan-3-yl]-[(3S)-3-[9-ethyl-8-(2-methylpyrimidin-5-yl)purin-6-yl]oxypyrrolidin-1-yl]methanone
    —— 8-(1-ethyl-5-methylpyrazol-4-yl)-9-methyl-6-[(3S)-1-pyrimidin-2-ylpyrrolidin-3-yl]oxypurine —— C20H23N9O
    8-(1-ethyl-5-methylpyrazol-4-yl)-9-methyl-6-[(3S)-1-pyrimidin-2-ylpyrrolidin-3-yl]oxypurine
    —— tert-butyl (3S)-3-[9-methyl-8-(2-methyl-1H-indol-7-yl)purin-6-yl]oxypyrrolidine-1-carboxylate —— C24H28N6O3
    tert-butyl (3S)-3-[9-methyl-8-(2-methyl-1H-indol-7-yl)purin-6-yl]oxypyrrolidine-1-carboxylate