| 1449143-63-8

• CAS: 1449143-63-8
• 化学式: C₁₀H₁₀FeO₅
• 分子量: 266.033
• InChiKey: GXQFVVIWECXYDV-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  None
• 重原子数：
  None
• 可旋转键数：
  None
• 环数：
  None
• sp3杂化的碳原子比例：
  None
• 拓扑面积：
  None
• 氢给体数：
  None
• 氢受体数：
  None

反应信息

• 作为反应物：
  描述：

  在 仲丁基锂 、 1,2-二碘乙烷 作用下， 以 四氢呋喃 、 环己烷 为溶剂， 反应 0.25h， 生成 、
  参考文献：
  名称：

  New cycloaddition/fragmentation strategies for preparing 5-7-5 and 5-7-6 fused tricyclic ring systems

  摘要：

  Tethering additional functionality to cyclobutadienyl iron tricarbonyl complexes provides new opportunities for the rapid construction of medium-ring-containing polycyclic compounds. Specifically, an intramolecular cycloaddition between cyclobutadiene and a tethered olefin, followed by an intramolecular cyclopropanation of the resulting cyclobutene-containing adduct generates highly strained pentacyclic intermediates. These compounds can then be relaxed thermally to generate 5-7-5 and 5-7-6 fused tricyclic ring systems that are shared with numerous natural products. (C) 2013 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tet.2013.05.129
• 作为产物：
  描述：

  ((hydroxymethyl)cyclobutadiene)tricarbonyliron 、 氯甲基甲基醚 在 N,N-二异丙基乙胺 作用下， 以95%的产率得到
  参考文献：
  名称：

  New cycloaddition/fragmentation strategies for preparing 5-7-5 and 5-7-6 fused tricyclic ring systems

  摘要：

  Tethering additional functionality to cyclobutadienyl iron tricarbonyl complexes provides new opportunities for the rapid construction of medium-ring-containing polycyclic compounds. Specifically, an intramolecular cycloaddition between cyclobutadiene and a tethered olefin, followed by an intramolecular cyclopropanation of the resulting cyclobutene-containing adduct generates highly strained pentacyclic intermediates. These compounds can then be relaxed thermally to generate 5-7-5 and 5-7-6 fused tricyclic ring systems that are shared with numerous natural products. (C) 2013 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tet.2013.05.129