[EN] PROTEIN BIOSENSORS, CROSS REACTIVE SENSOR ARRAYS AND METHODS OF USE THEREOF<br/>[FR] BIOCAPTEURS PROTÉINIQUES, RÉSEAUX DE CAPTEURS À RÉACTION CROISÉE ET PROCÉDÉS D'UTILISATION CORRESPONDANTS
申请人:YEDA RES & DEV
公开号:WO2014102806A1
公开(公告)日:2014-07-03
The present invention is directed to fluorescent protein biosensors based on oligonucleotide cross reactive sensor arrays including a selective and a non-selective protein binding domain for protein detection. Interaction of different protein isoforms with the sensors of this invention yields a unique optical signature for each protein. The unique optical signature allows differentiating between closely related protein isoforms and diagnosing diseases and disorders associated with the proteins also in biofluids.