(5-bromo-6-chloro-1H-indol-3-yl) hydrogen phosphate;(4-methylphenyl)azanium

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 有机磷酸及其衍生物
• 英文名称: (5-bromo-6-chloro-1H-indol-3-yl) hydrogen phosphate;(4-methylphenyl)azanium
• 化学式: C15H15BrClN2O4P
• 分子量: 433.62
• InChiKey: WUHVYTJTZAKPOS-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.63
• 重原子数：
  24
• 可旋转键数：
  2
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.07
• 拓扑面积：
  109
• 氢给体数：
  4
• 氢受体数：
  5

文献信息

• COMPOSITIONS AND MEANS FOR DIAGNOSING MICROBIAL INFECTIONS
  申请人：Statens Serum Institut

  公开号：EP2181330A1

  公开（公告）日：2010-05-05
• Molecularly Imprinted Polymers for Use as Imaging and Therapeutics Agents
  申请人：Jones Robert

  公开号：US20120093720A1

  公开（公告）日：2012-04-19

  The invention described herein provides biocompatible molecularly imprinted polymers (MIPs) that are non-toxic, water soluble, small molecular weight, and degradable in a living body. The MIPs are capable of binding to all or a portion of a specific target macromolecule associated with a disease located within the living body and they are derivatized for stealth for in vivo applications to avoid the reticuloendothelial system. The MIPs of the invention are functionalized to an amine or carboxyl group and are derivatized with an imaging and/or therapeutic agent for taking images of the disease and/or for providing therapy. The macromolecule can be selected from a group consisting of proteins, glycoproteins, lipoproteins, peptidoglycans, peptides, polypeptides, polynucleotides, and polysaccharides. The invention described herein also provides methods and kits wherein MIPs of the invention can be employed as targeted imaging and therapeutic agents.
• US5998156A
  申请人：——

  公开号：US5998156A

  公开（公告）日：1999-12-07
• US6251618B1
  申请人：——

  公开号：US6251618B1

  公开（公告）日：2001-06-26
• US8753875B2
  申请人：——

  公开号：US8753875B2

  公开（公告）日：2014-06-17