Phosphoric acid, dibutyl 2-hydroxyethyl ester | 130525-77-8

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 有机磷酸及其衍生物
• 英文名称: Phosphoric acid, dibutyl 2-hydroxyethyl ester
• 英文别名: dibutyl 2-hydroxyethyl phosphate
• CAS: 130525-77-8
• 化学式: C₁₀H₂₃O₅P
• 分子量: 254.26
• InChiKey: IHYIUHPLGDTUKJ-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.3
• 重原子数：
  16
• 可旋转键数：
  11
• 环数：
  0.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  65
• 氢给体数：
  1
• 氢受体数：
  5

文献信息

• [EN] PRODRUGS OF OXAZOLIDINONE CETP INHIBITORS<br/>[FR] PROMÉDICAMENTS D'INHIBITEURS DE CETP À BASE D'OXAZOLIDINONE
  申请人：MERCK SHARP & DOHME

  公开号：WO2010039474A1

  公开（公告）日：2010-04-08

  The compounds of Formula I are prodrugs of CETP inhibitors having a central oxazolidinone ring. The compounds cyclize by the elimination of HX to form an oxazolidinone ring after administration to a patient.

  公式I的化合物是CETP抑制剂的前药，具有中心噁唑烷酮环。这些化合物在给药后通过消除HX而环化，形成噁唑烷酮环。
• PRODRUGS OF OXAZOLIDINONE CETP INHIBITORS
  申请人：Mills Sander G.

  公开号：US20110218177A1

  公开（公告）日：2011-09-08

  The compounds of Formula I are pro-drugs of CETP inhibitors having a central oxazolidinone ring. The compounds cyclize by the elimination of HX to form an oxazolidinone ring after administration to a patient.

  公式I的化合物是具有中心噁唑烷环的CETP抑制剂前药。这些化合物在给患者使用后通过HX的消除环化形成噁唑烷环。
• Substituted triazine-capped polyphenylene ethers
  申请人：GENERAL ELECTRIC COMPANY

  公开号：EP0461434A2

  公开（公告）日：1991-12-18

  Substituted alkoxy- or alkylthiochlorotriazines wherein the substituents on the alkoxy groups are chlorine, bromine or dialkylphosphato are useful as capping agents for polyphenylene ethers. The capped polyphenylene ethers form copolymers with other polymers containing nucleophilic groups, including polyesters, polyamides and functionalized olefin polymers. Such copolymers serve as compatibilizers in the formation of blends having high impact strength.

  取代的烷氧基或烷基硫代氯三嗪（其中烷氧基上的取代基为氯、溴或二烷基膦）可用作聚苯醚的封端剂。封端的聚苯醚可与其他含有亲核基团的聚合物（包括聚酯、聚酰胺和官能化烯烃聚合物）形成共聚物。这种共聚物在形成具有高冲击强度的混合物时可用作相容剂。
• Copolymer-containing compositions from substituted triazine-capped polyphenylene ethers
  申请人：GENERAL ELECTRIC COMPANY

  公开号：EP0462410A2

  公开（公告）日：1991-12-27

  Substituted alkoxy- or alkylthiochlorotriazines wherein the substituents on the alkoxy groups are chlorine, bromine or dialkylphosphato are useful as capping agents for polyphenylene ethers. The capped polyphenylene ethers form copolymers with other polymers containing nucleophilic groups, including polyesters, polyamides and functionalized olefin polymers. Such copolymers serve as compatibilizers in the formation of blends having high impact strength.

  取代的烷氧基或烷基硫代氯三嗪（其中烷氧基上的取代基为氯、溴或二烷基膦）可用作聚苯醚的封端剂。封端的聚苯醚可与其他含有亲核基团的聚合物（包括聚酯、聚酰胺和官能化烯烃聚合物）形成共聚物。这种共聚物在形成具有高冲击强度的混合物时可用作相容剂。
• Substituted chlorotriazines useful for reactive capping of polyphenylene ethers
  申请人：GENERAL ELECTRIC COMPANY

  公开号：EP0461433A2

  公开（公告）日：1991-12-18

  Substituted alkoxy- or alkylthiochlorotriazines wherein the substituents on the alkoxy groups are chlorine, bromine or dialkylphosphato are useful as capping agents for polyphenylene ethers. The capped polyphenylene ethers form copolymers with other polymers containing nucleophilic groups, including polyesters, polyamides and functionalized olefin polymers. Such copolymers serve as compatibilizers in the formation of blends having high impact strength.

  取代的烷氧基或烷基硫代氯三嗪（其中烷氧基上的取代基为氯、溴或二烷基膦）可用作聚苯醚的封端剂。封端的聚苯醚可与其他含有亲核基团的聚合物（包括聚酯、聚酰胺和官能化烯烃聚合物）形成共聚物。这种共聚物在形成具有高冲击强度的混合物时可用作相容剂。