4-Nitrophenylphosphatebis(cyclohexylammonium)salt

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 有机磷酸及其衍生物
• 英文名称: 4-Nitrophenylphosphatebis(cyclohexylammonium)salt
• 英文别名: cyclohexylazanium;(4-nitrophenyl) phosphate
• 化学式: C18H32N3O6P
• 分子量: 417.4
• InChiKey: KXNNUYCXODNFBD-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.62
• 重原子数：
  28
• 可旋转键数：
  2
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.67
• 拓扑面积：
  165
• 氢给体数：
  4
• 氢受体数：
  8

反应信息

• 作为产物：
  描述：

  Bis<2-(methylsulfonyl)ethyl> p-nitrophenyl phosphate 、 盐酸环己胺 、 sodium hydroxide 、 甲醇 生成 4-Nitrophenylphosphatebis(cyclohexylammonium)salt
  参考文献：
  名称：

  BELD, A.;CLAESEN, C. A. A.;ROESMA, E. S., REC. TRAV. CHIM. PAYS-BAS, 1984, 103, N 6, 196-202

  摘要：

  DOI：

文献信息

• A substantially pure rheumatoid arthritis specific protein and an antibody against the same
  申请人：ASAHI MEDICAL Co., Ltd.

  公开号：EP0175310A1

  公开（公告）日：1986-03-26

  A substantially pure rheumatoid arthritis specific protein (RASP) and an antibody against the rheumatoid arthritis specific protein (anti-RASP antibody) are disclosed. The RASP is found specifically in the serum or plasma of a patient suffering from rheumatoid arthritis, and may be detected using an anti-RASP antibody easily and effectively. Therefore, the anti-RASP antibody of the present invention is useful for the diagnosis of rheumatoid arthritis by the criterion of the presence of RASP.

  本研究公开了一种纯度很高的类风湿关节炎特异性蛋白（RASP）和一种抗类风湿关节炎特异性蛋白的抗体（抗 RASP 抗体）。类风湿性关节炎患者的血清或血浆中含有特异性的 RASP，使用抗 RASP 抗体可以方便有效地检测到 RASP。因此，本发明的抗 RASP 抗体有助于以 RASP 的存在为标准诊断类风湿性关节炎。
• Integral multilayer analytical element for use in the measurement of alkaline phosphatase acitivity
  申请人：FUJI PHOTO FILM CO., LTD.

  公开号：EP0182179A1

  公开（公告）日：1986-05-28

  An integral multilayer analytical element for use in the measurement of alkaline phosphatase activity, which comprises a porous spreading layer of woven fabric or knitted fabric containing an alkaline phosphatase-sensitive self-developing substrate, a buffer layer containing one or more compounds functioning as a phosphoric acid acceptor and a buffering agent and a support layer in a laminated form.

  一种用于测量碱性磷酸酶活性的整体式多层分析元件，它包括多孔的机织物或针织物铺展层，其中含有对碱性磷酸酶敏感的自显影基质；缓冲层，其中含有一种或多种用作磷酸受体和缓冲剂的化合物；以及层压形式的支撑层。
• Theophylline assay
  申请人：MediSense, Inc.

  公开号：EP0370607A1

  公开（公告）日：1990-05-30

  An electrochemical method of assay for determining theophylline in a sample comprises contacting the sample with an alkaline phosphatase and with a phosphate ester which is a substrate for the alkaline phosphatase and from which an electroactive compound can be released by catalytic activity of the alkaline phosphatase, electrochemically oxidising the electroactive compound, detecting current arising from the electrochemical oxidation, comparing the detected current with that obtained from a standardised electrochemical oxidation, and evaluating the level of theophylline in the sample.

  一种测定样品中茶碱含量的电化学方法包括：将样品与碱性磷酸酶和磷酸酯接触，磷酸酯是碱性磷酸酶的底物，碱性磷酸酶的催化活性可从中释放出一种电活性化合物；电化学氧化电活性化合物；检测电化学氧化产生的电流；将检测到的电流与标准化电化学氧化得到的电流进行比较；以及评估样品中的茶碱含量。
• US4742157A
  申请人：——

  公开号：US4742157A

  公开（公告）日：1988-05-03
• US4863850A
  申请人：——

  公开号：US4863850A

  公开（公告）日：1989-09-05