1-Aethyl-cyclopentamethylenphosphinsulfid | 52032-42-5

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 磷环化合物
• 英文名称: 1-Aethyl-cyclopentamethylenphosphinsulfid
• 英文别名: 1-Aethylphosphorinan-sulfid；1-ethyl-phosphinane 1-sulfide；1-ethyl-phosphorinane sulfide；1-Ethyl-1-sulfanylidene-1lambda5-phosphinane；1-ethyl-1-sulfanylidene-1λ5-phosphinane
• CAS: 52032-42-5
• 化学式: C₇H₁₅PS
• 分子量: 162.236
• InChiKey: XHTFUIQYDQTJHK-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.3
• 重原子数：
  9
• 可旋转键数：
  1
• 环数：
  1.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  32.1
• 氢给体数：
  0
• 氢受体数：
  1

反应信息

• 作为产物：
  描述：

  1-Ethyl-phosphorinan 在 sulfur 作用下， 以 苯 为溶剂， 生成 1-Aethyl-cyclopentamethylenphosphinsulfid
  参考文献：
  名称：

  Issleib,K.; Haeusler,S., Chemische Berichte, 1961, vol. 94, p. 113 - 117

  摘要：

  DOI：

文献信息

• PROCESS FOR PRODUCING OPTICALLY ACTIVE DIMER OF PHOSPHORUS HETEROCYCLE
  申请人：NIPPON CHEMICAL INDUSTRIAL COMPANY LIMITED

  公开号：EP1650216A1

  公开（公告）日：2006-04-26

  Primary phosphine represented by formula (1):         [Chem. 1] R-PH2     (1) (wherein R represents a linear, branched, or cyclic alkyl group having 2 to 20 carbon atoms) is reacted with a compound represented by formula (2):         [Chem. 2] Y-CnH2n-Y     (2) (wherein Y represents a halogen atom or a leaving group selected from -OTs, -OTf, and -OMs, and n represents a number of 3 to 6) in the presence of a base; the product is reacted with boron trihydride, oxygen, or sulfur to obtain a phosphorus heterocyclic compound represented by formula (3): (wherein R represents the same as the above, n represents a number of 1 to 4, X represents a boron trihydride group, an oxygen atom, or a sulfur atom, and === represents a single bond when X is a boron trihydride group or a double bond when X is an oxygen atom or sulfur atom); the resultant compound is dimerized to produce a phosphorus heterocyclic dimer represented by formula (4): (wherein R, n, and X represent the same as the above); and then oxygen, sulfur, or borane is removed from the resultant phosphorus heterocyclic dimer to obtain an optically active phosphorus heterocyclic dimer represented by formula (5): (wherein R and n represent the same as the above).

  式 (1) 所代表的伯胺膦： [化学 1] R-PH2 (1) (其中 R 代表具有 2 至 20 个碳原子的直链、支链或环状烷基）与式 (2) 所代表的化合物反应： [化学 2] Y-CnH2n-Y (2) (其中 Y 代表卤原子或选自-OTs、-OTF 和-OMs 的离去基团，n 代表 3 至 6 的数字）在碱存在下反应；产物与三氢化硼、氧或硫反应，得到式（3）代表的磷杂环化合物： (其中 R 代表与上述相同，n 代表 1 至 4 的数字，X 代表三硼氢基、氧原子或硫原子，当 X 为三硼氢基时，===== 代表单键，当 X 为氧原子或硫原子时，===== 代表双键)；将所得化合物二聚，生成式(4)代表的磷杂环二聚物： (其中 R、n 和 X 的代表与上述相同）；然后从得到的磷杂环二聚体中除去氧、硫或硼烷，得到由式（5）表示的具有光学活性的磷杂环二聚体： (其中 R 和 n 的代表与上述相同）。
• Process for producing optically active dimer of phosphorus heterocycle
  申请人：Oohara Nobuhiko

  公开号：US20060211888A1

  公开（公告）日：2006-09-21

  Primary phosphine represented by formula (1): [Chem. 1] R—PH 2 (1) (wherein R represents a linear, branched, or cyclic alkyl group having 2 to 20 carbon atoms) is reacted with a compound represented by formula (2): [Chem. 2] Y—C n H 2n —Y  (2) (wherein Y represents a halogen atom or a leaving group selected from —OTs, —OTf, and —OMs, and n represents a number of 3 to 6) in the presence of a base; the product is reacted with boron trihydride, oxygen, or sulfur to obtain a phosphorus heterocyclic compound represented by formula (3): (wherein R represents the same as the above, n represents a number of 1 to 4, X represents a boron trihydride group, an oxygen atom, or a sulfur atom, and === represents a single bond when X is a boron trihydride group or a double bond when X is an oxygen atom or sulfur atom); the resultant compound is dimerized to produce a phosphorus heterocyclic dimer represented by formula (4): (wherein R, n, and X represent the same as the above); and then oxygen, sulfur, or borane is removed from the resultant phosphorus heterocyclic dimer to obtain an optically active phosphorus heterocyclic dimer represented by formula (5): (wherein R and n represent the same as the above).

  由式（1）表示的伯胺膦：[化学式 1］ R-PH 2 (1) (其中 R 代表具有 2 至 20 个碳原子的直链、支链或环状烷基）与式 (2) 所代表的化合物反应：[化学式 2］ Y-C n H 2n -Y (2) (其中 Y 代表卤原子或选自-OTs、-OTF 和-OMs 的离去基团，n 代表 3 至 6 的数字），在碱存在下；产物与三酸化硼、氧或硫反应，得到由式（3）代表的磷杂环化合物： (其中 R、n 和 X 的代表与上述相同）；然后从得到的磷杂环二聚体中除去氧、硫或硼烷，得到由式（5）代表的具有光学活性的磷杂环二聚体： (其中 R 和 n 的代表与上述相同）。
• Issleib,K.; Haeusler,S., Chemische Berichte, 1961, vol. 94, p. 113 - 117
  作者：Issleib,K.、Haeusler,S.

  DOI：——

  日期：——
• US7411096B2
  申请人：——

  公开号：US7411096B2

  公开（公告）日：2008-08-12
• Carbon-13 magnetic resonance spectral study of some phosphorinanes and their 1-sulfides
  作者：Sidney I. Featherman、Shin O. Lee、Louis D. Quin

  DOI：10.1021/jo00933a017

  日期：1974.9