三[2-(全氟辛基)乙基]磷酸酯 | 149790-22-7

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 有机磷酸及其衍生物
• 中文名称: 三[2-(全氟辛基)乙基]磷酸酯
• 中文别名: 磷酸三[2-(全氟辛基)乙酯]
• 英文名称: Tris(1H,1H,2H,2H-perfluorodecyl)phosphate
• 英文别名: Tris[2-(perfluorooctyl)ethyl] Phosphate；tris(3,3,4,4,5,5,6,6,7,7,8,8,9,9,10,10,10-heptadecafluorodecyl) phosphate
• CAS: 149790-22-7
• 化学式: C₃₀H₁₂F₅₁O₄P
• 分子量: 1436.32
• InChiKey: LWAHZPPAFSQPGA-UHFFFAOYSA-N

物化性质

• 熔点：
  102-106°C
• 溶解度：
  可溶于甲醇（非常轻微，加热），吡啶（轻微）

计算性质

• 辛醇/水分配系数(LogP)：
  18
• 重原子数：
  86
• 可旋转键数：
  30
• 环数：
  0.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  44.8
• 氢给体数：
  0
• 氢受体数：
  55

反应信息

• 作为反应物：
  描述：

  三[2-(全氟辛基)乙基]磷酸酯 、 四氯化锡 以 二氯甲烷 为溶剂， 反应 24.0h， 以65%的产率得到
  参考文献：
  名称：

  带有多氟烷基的磷酰基配体的四氯化锡配合物的合成、表征和溶解行为

  摘要：

  新型八面体四氯化锡配合物SnCl 4 .2L (L = RR 2 N) 2 P(O)O(CH 2 ) 2 C 6 F 13的合成与表征；NR 2  = NC 5 H 10 ( 1 ); NC 4 H 8 ( 2 ); N(CH 2 CH 2 ) 2 O ( 3 ); NEt 2 ( 4 ), L = RR 2 N) 2 P(O)O(CH 2 ) 2 C 8F 17 ; NR 2  = NC 5 H 10 ( 5 ); NC 4 H 8 ( 6 ); N(CH 2 CH 2 ) 2 O ( 7 ), L = R 2 NP(O)(O(CH 2 ) 2 C 6 F 13 ) 2 ; NC 5 H 10 ( 8 ); NC 4 H 8 ( 9 ); N(CH 2 CH 2 ) 2 O ( 10); NEt 2 ( 11 ), L = R 2 NP(O)(O(CH 2 ) 2 C 8 F 17 ) 2

  DOI：

  10.1016/j.ica.2022.120803

文献信息

• Fluorous multiphase catalyst or reagent systems, and processes using them
  申请人：EXXON RESEARCH AND ENGINEERING COMPANY

  公开号：EP0633062A1

  公开（公告）日：1995-01-11

  Stoichiometric and catalytic chemical transformations may be carried out in solution using novel fluorous multiphase systems (FMS). "Fluorous" denotes a carbon-fluorine bond rich organic molecule derived by replacing hydrogen atoms bonded to carbon atoms with fluorine. The FMS consists of a fluorous phase containing a fluorous solvent, typically a fluorocarbon or a fluorohydrocarbon (with or without substituent groups), and a reagent or a catalyst containing a sufficient number of fluorous moieties to render it preferentially soluble in the fluorous solvent and located at the interface of the fluorous and nonfluorous phases. The nonfluorous (i.e. the second) solvent, may be any known organic or nonorganic solvent(s) with limited or no solubility in the fluorous solvent that is effective for dissolving the reactants and/or separating the reaction products (e.g., a nonfluorous solvent having a Hildebrand solubility parameter of at least about 18.0 MPa½). The reaction can occur simultaneously in the fluorous phase and at the interface of the phases. The FMS reagents and FMS catalysts contain sufficient number of fluorous moieties to render them preferentially soluble into the fluorous phase and at the interface without impairing the efficacy or participation of the catalyst or reagent in the reaction which is maintained in a liquid or fluid phase. The preferred fluorous moieties are linear, branched and carbocyclic fluorocarbon alkyl chains with high carbon numbers that enable the catalyst or reagent to remain fluorous-phase compatible. The fluorous moieties may also contain O, S, N, P, As and Si, that assist in rendering the catalysts and reagents fluorous phase compatible. The FMS reagents and catalysts can be prepared by (1) fluorination (i.e., replacement of C-H bonds with fluorine); (2) fluorofunctionalization, e.g., the attachment of fluorous moieties to the reagents or catalysts; or (3) by total synthesis. The fluorous multiphase systems have utility to facilitate the separation of the FMS catalyst or spent FMS reagent, which has utility in the design and synthesis of catalysts and reagents with high product selectivity, resulting in especially environmentally friendly processes.

  利用新型多相系统（FMS）可以在溶液中进行化学计量和催化化学转化。氟 "是指通过用氟取代与碳原子结合的氢原子而得到的富含碳-氟键的有机分子。FMS 由一个含氟相和一个试剂或催化剂组成，前者含有氟溶剂，通常是碳氟化合物或碳氢化合物（带或不带取代基），后者含有足够数量的氟分子，使其优先溶于氟溶剂，并位于氟相和非氟相的界面上。非流相（即第二种）溶剂可以是任何已知的有机或无机溶剂，它们在流相溶剂中的溶解度有限或没有溶解度，但对溶解反应物和/或分离反应产物有效（例如，希尔德布兰德溶解度参数至少为约 18.0 MPa½的非流相溶剂）。反应可同时在流相和两相界面上进行。FMS 试剂和 FMS 催化剂含有足够数量的含氟分子，使其优先溶解在含氟相和界面中，而不影响催化剂或试剂在液相或流体相中反应的功效或参与。优选的含氟分子为高碳原子数的线性、支链和碳环氟碳烷基链，可使催化剂或试剂保持氟相相容性。多孔分子还可能含有 O、S、N、P、As 和 Si，有助于使催化剂和试剂具有多孔相容性。氟多相试剂和催化剂可通过以下方法制备：(1) 氟化（即用氟取代 C-H 键）；(2) 氟官能化，例如在试剂或催化剂上附着多孔分子；或 (3) 全合成。 氟多相系统可用于促进氟化烃催化剂或废氟化烃试剂的分离，这在设计和合成具有高产品选择性的催化剂和试剂方面非常有用，可产生特别环保的工艺。
• US5463082A
  申请人：——

  公开号：US5463082A

  公开（公告）日：1995-10-31
• US5981422A
  申请人：——

  公开号：US5981422A

  公开（公告）日：1999-11-09
• Synthesis, characterization and solution behaviour of tin tetrachloride complexes with phosphoryl ligands bearing polyfluoroalkyl groups
  作者：Fahima Laribi、M.A.K. Sanhoury、H. Mechi、D. Merlet、I. Chehidi

  DOI：10.1016/j.ica.2022.120803

  日期：2022.4

  temperature, the existence of phosphoramidate complexes as mixtures of cis and trans isomers with predominance of the trans form for all complexes except the phosphate adduct 14, which shows only the cis isomer. The difference could be interpreted in terms of the Lewis basicity of the ligand and steric factors. The solution behavior of these complexes in the presence of excess ligand was also investigated

  新型八面体四氯化锡配合物SnCl 4 .2L (L = RR 2 N) 2 P(O)O(CH 2 ) 2 C 6 F 13的合成与表征；NR 2  = NC 5 H 10 ( 1 ); NC 4 H 8 ( 2 ); N(CH 2 CH 2 ) 2 O ( 3 ); NEt 2 ( 4 ), L = RR 2 N) 2 P(O)O(CH 2 ) 2 C 8F 17 ; NR 2  = NC 5 H 10 ( 5 ); NC 4 H 8 ( 6 ); N(CH 2 CH 2 ) 2 O ( 7 ), L = R 2 NP(O)(O(CH 2 ) 2 C 6 F 13 ) 2 ; NC 5 H 10 ( 8 ); NC 4 H 8 ( 9 ); N(CH 2 CH 2 ) 2 O ( 10); NEt 2 ( 11 ), L = R 2 NP(O)(O(CH 2 ) 2 C 8 F 17 ) 2