三鲸蜡基磷酸酯 | 56827-95-3

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 有机磷酸及其衍生物
• 中文名称: 三鲸蜡基磷酸酯
• 中文别名: 三鲸蜡醇磷酸酯
• 英文名称: hexadecyl phosphate
• 英文别名: cetyl phosphate；phosphoric acid trihexadecyl ester；Phosphorsaeure-trihexadecylester；Trihexadecylphosphat；Triacetylphosphat；Tricetyl phosphate；trihexadecyl phosphate
• CAS: 56827-95-3
• 化学式: C₄₈H₉₉O₄P
• 分子量: 771.285
• InChiKey: KENFVQBKAYNBKN-UHFFFAOYSA-N

物化性质

• 熔点：
  61 °C
• 沸点：
  616.5±23.0 °C(Predicted)
• 密度：
  0.892±0.06 g/cm3(Predicted)
• LogP：
  22.172 (est)

计算性质

• 辛醇/水分配系数(LogP)：
  22.8
• 重原子数：
  53
• 可旋转键数：
  48
• 环数：
  0.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  44.8
• 氢给体数：
  0
• 氢受体数：
  4

反应信息

• 作为产物：
  描述：

  1-十六烷醇 、 alkaline earth salt of/the/ methylsulfuric acid 在 乙醚 作用下， 生成 三鲸蜡基磷酸酯
  参考文献：
  名称：

  Plimmer; Burch, Journal of the Chemical Society, 1929, p. 298

  摘要：

  DOI：

文献信息

• [EN] TRIAZINE DERIVATIVES AS UV ABSORBERS<br/>[FR] DERIVES DE LA TRIAZINE UTILISES COMME ABSORBANTS U.V.
  申请人：CIBA SC HOLDING AG

  公开号：WO2004064797A1

  公开（公告）日：2004-08-05

  The present invention relates to new compounds of formula (I), wherein R1, R2, R3, R4, R5, R6, R7, and R8 independently from each other are hydrogen; C1-C18alkyl; C2-C18alkenyl; C5-C7,cycloalkyl; C1-C6alkylene-C5- C7,cycloalkyl; R9 is hydrogen; C1-C18alkyl; C2-C18alkenyl; C5-C7cycloalkyl; C1-C6alkylene-C5-C7cycloalkyl; C6-C10aryl; A is-S-; -O- or -NR10-, wherein R10 has the same meanings as R9; X is COOR11; CONR12R13; SO3,R14; or SO2NR15R16, wherein R11, R12,R13, R14,R15, and R16, have independently from each other the same meanings as R9; to their preparation and to their use as UV absorbers in cosmetic and pharmaceutical formulations.

  本发明涉及公式（I）的新化合物，其中R1、R2、R3、R4、R5、R6、R7和R8彼此独立地是氢；C1-C18烷基；C2-C18烯基；C5-C7环烷基；C1-C6烷基-C5-C7环烷基；R9是氢；C1-C18烷基；C2-C18烯基；C5-C7环烷基；C1-C6烷基-C5-C7环烷基；C6-C10芳基；A是-S-；-O-或-NR10-，其中R10具有与R9相同的含义；X是COOR11；CONR12R13；SO3R14；或SO2NR15R16，其中R11、R12、R13、R14、R15和R16彼此独立地具有与R9相同的含义；以及它们的制备和它们作为化妆品和药用配方中的紫外线吸收剂的用途。
• AhR mediators
  申请人：Krutmann Jean

  公开号：US20090028804A1

  公开（公告）日：2009-01-29

  The invention relates to a method for finding and assessing agonists [and] antagonists of the aryl hydrocarbon receptor (Ah receptor; AhR), to the agonists and antagonists themselves and to uses thereof.

  这项发明涉及一种用于寻找和评估芳香族羟基化合物受体（Ah受体；AhR）的激动剂和拮抗剂的方法，以及这些激动剂和拮抗剂本身及其用途。
• [EN] COMPOUNDS USEFUL FOR THE TREATMENT AND/OR CARE OF THE SKIN, HAIR, NAILS AND/OR MUCOUS MEMBRANES<br/>[FR] COMPOSÉS UTILES DANS LE TRAITEMENT ET/OU LES SOINS DE LA PEAU, DES CHEVEUX, DES ONGLES ET/OU DES MUQUEUSES
  申请人：LUBRIZOL ADVANCED MAT INC

  公开号：WO2019008452A1

  公开（公告）日：2019-01-10

  A compound of formula (I) R1-Wm-Xn-AA1-AA2-AA3-AA4-AA5-AA6-AA7-AA8-AA9-Yp-Zq-R2 wherein AA1 is Phe; AA2 is Trp; AA3 is selected from the group consisting of Met, Leu and lie; AA4 is selected from the group consisting of Lys, Arg and Gin; AA5 is Arg; AA6 is Lys; AA7 is selected from the group consisting of Arg, Lys and His; AA8 is selected from the group consisting of Val, lie, Leu and Met; and AA9 is Pro, useful in the treatment and/or care of the skin, hair, nails and/or mucous membranes, in particular for improving the barrier function of the skin, for energising the skin and as an anti- aging agent.

  一种具有以下结构的化合物（I）R1-Wm-Xn-AA1-AA2-AA3-AA4-AA5-AA6-AA7-AA8-AA9-Yp-Zq-R2，其中AA1为Phe；AA2为Trp；AA3选自Met、Leu和Ile组成的群体；AA4选自Lys、Arg和Gln组成的群体；AA5为Arg；AA6为Lys；AA7选自Arg、Lys和His组成的群体；AA8选自Val、Ile、Leu和Met组成的群体；AA9为Pro。该化合物在治疗和/或护理皮肤、头发、指甲和/或粘膜方面具有用途，特别用于改善皮肤的屏障功能，激活皮肤并作为抗衰老剂。
• BITTER TASTE MODIFIERS INCLUDING SUBSTITUTED 1-BENZYL-3-(1-(ISOXAZOL-4-YLMETHYL)-1H-PYRAZOL-4-YL)IMIDAZOLIDINE-2,4-DIONES AND COMPOSITIONS THEREOF
  申请人：SENOMYX, INC.

  公开号：US20160376263A1

  公开（公告）日：2016-12-29

  The present invention includes compounds and compositions known to modify the perception of bitter taste, and combinations of said compositions and compounds with additional compositions, compounds, and products. Exemplary compositions comprise one or more of the following: cooling agents; inactive drug ingredients; active pharmaceutical ingredients; food additives or foodstuffs; flavorants, or flavor enhancers; food or beverage products; bitter compounds; sweeteners; bitterants; sour flavorants; salty flavorants; umami flavorants; plant or animal products; compounds known to be used in pet care products; compounds known to be used in personal care products; compounds known to be used in home products; pharmaceutical preparations; topical preparations; cannabis-derived or cannabis-related products; compounds known to be used in oral care products; beverages; scents, perfumes, or odorants; compounds known to be used in consumer products; silicone compounds; abrasives; surfactants; warming agents; smoking articles; fats, oils, or emulsions; and/or probiotic bacteria or supplements.

  本发明涵盖已知用于改变苦味感知的化合物和组合物，以及所述组合物和化合物与额外的组合物、化合物和产品的组合。示例组合物包括以下一种或多种：冷却剂；无活性药物成分；活性药用成分；食品添加剂或食品；调味剂或调味增强剂；食品或饮料产品；苦味化合物；甜味剂；苦味剂；酸味调味剂；咸味调味剂；鲜味调味剂；植物或动物产品；已知用于宠物护理产品中的化合物；已知用于个人护理产品中的化合物；已知用于家用产品中的化合物；制药制剂；局部制剂；大麻衍生或与大麻相关的产品；已知用于口腔护理产品中的化合物；饮料；香味、香水或除臭剂；已知用于消费品中的化合物；硅化合物；磨料；表面活性剂；发热剂；吸烟物品；脂肪、油脂或乳化剂；和/或益生菌或补充剂。
• Low-emulsifier or emulsifier-free systems of the oil-in-water type with a content of stabilizers and an amino-substituted hydroxybenzophenone
  申请人：——

  公开号：US20030124158A1

  公开（公告）日：2003-07-03

  Cosmetic or dermatological preparations which represent finely disperse systems of the oil-in-water type, comprising a) an oil phase, b) a water phase, c) one or more stabilizers, d) at most 2.00% by weight of one or more emulsifiers, and e) an amino-substituted hydroxybenzophenone of the formula I 1

  化妆品或皮肤科制剂，代表油包水型的细分散系统，包括 a) 油相， b) 水相， c) 一种或多种稳定剂， d) 最多占总重量的2.00%的一种或多种乳化剂，以及 e) 公式I的氨基取代羟基苯酮 1