dunalianoside D

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 糖脂
• 英文名称: dunalianoside D
• 英文别名: [(2R,3S,4S,5R,6S)-3,4,5-trihydroxy-6-(4-hydroxy-3-methoxyphenoxy)oxan-2-yl]methyl 3-(3,4-dihydroxyphenyl)prop-2-enoate
• 化学式: C₂₂H₂₄O₁₁
• 分子量: 464.426
• InChiKey: QBCURMGOSCOETK-MIUGBVLSSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.8
• 重原子数：
  33
• 可旋转键数：
  8
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.32
• 拓扑面积：
  175
• 氢给体数：
  6
• 氢受体数：
  11

反应信息

• 作为反应物：
  描述：

  dunalianoside D 在 盐酸 作用下， 以 水 为溶剂， 反应 2.0h， 生成 葡萄糖
  参考文献：
  名称：

  Hepatoprotective phenylethanoid glycosides from Cirsium setosum

  摘要：

  Two new phenylethanoid glycosides, namely -D-glucopyranoside, 1-O-(7S)-7-(3-methoxyl-4-hydroxyphenyl)-7-methoxyethyl-3--L-rhamnopyranosyl-4-[(8E)-7-(3-methoxyl-4-hydroxyphenyl)-8-propenoate] (1) and -D-glucopyranoside, 1-O-(7S)-7-(3-methoxyl-4-hydroxyphenyl)-7-methoxyethyl-3 ''-alpha-L-rhamnopyranosyl-4-[(8E)-7-(4-hydroxyphenyl)-8-propenoate] (2), together with six phenylethanoid glycosides were isolated from Cirsium setosum. Their structures were elucidated by their spectroscopic data and references. Compounds 2, 4, 5, 7 and 8 (10M) exhibited moderate hepatoprotective activities. Compounds (3-8) were obtained from this plant for the first time.[GRAPHCIS].

  DOI：

  10.1080/14786419.2015.1084304

文献信息

• Hepatoprotective phenylethanoid glycosides from <i>Cirsium setosum</i>
  作者：Qinge Ma、Yongming Guo、Baomin Luo、Wenmin Liu、Rongrui Wei、Chunxia Yang、Chenghua Ding、Xuefeng Xu、Minghui He

  DOI：10.1080/14786419.2015.1084304

  日期：2016.8.17

  Two new phenylethanoid glycosides, namely -D-glucopyranoside, 1-O-(7S)-7-(3-methoxyl-4-hydroxyphenyl)-7-methoxyethyl-3--L-rhamnopyranosyl-4-[(8E)-7-(3-methoxyl-4-hydroxyphenyl)-8-propenoate] (1) and -D-glucopyranoside, 1-O-(7S)-7-(3-methoxyl-4-hydroxyphenyl)-7-methoxyethyl-3 ''-alpha-L-rhamnopyranosyl-4-[(8E)-7-(4-hydroxyphenyl)-8-propenoate] (2), together with six phenylethanoid glycosides were isolated from Cirsium setosum. Their structures were elucidated by their spectroscopic data and references. Compounds 2, 4, 5, 7 and 8 (10M) exhibited moderate hepatoprotective activities. Compounds (3-8) were obtained from this plant for the first time.[GRAPHCIS].