乙基吡嗪基磷酸酯 | 7359-55-9

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 有机磷酸及其衍生物
• 中文名称: 乙基吡嗪基磷酸酯
• 英文名称: Thionazin-oxon
• 英文别名: diethyl pyrazin-2-yl phosphate
• CAS: 7359-55-9
• 化学式: C₈H₁₃N₂O₄P
• 分子量: 232.17
• InChiKey: HMFWESVGJAXCEJ-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.3
• 重原子数：
  15
• 可旋转键数：
  6
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.5
• 拓扑面积：
  70.5
• 氢给体数：
  0
• 氢受体数：
  6

安全信息

• 危险等级：
  6.1(a)
• 危险类别：
  6.1(a)

文献信息

• Methods and compositions for increasing the efficacy of biologically-active ingredients
  申请人：Windsor Brian J.

  公开号：US20060276339A1

  公开（公告）日：2006-12-07

  The invention provides methods and compositions for modulating the sensitivity of cells to cytotoxic compounds and other active agents. In accordance with the invention, compositions are provided comprising combinations of ectophosphatase inhibitors and active agents. Active agents include antibiotics, fungicides, herbicides, insecticides, chemotherapeutic agents, and plant growth regulators. By increasing the efficacy of active agents, the invention allows use of compositions with lowered concentrations of active ingredients.
• NOVEL PHOSPHOTRIESTERASE ENZYMES, METHODS AND COMPOSITIONS RELATED THERETO
  申请人：Polytechnic Institute of New York University

  公开号：US20160083702A1

  公开（公告）日：2016-03-24

  The instant invention provides methods and related compositions for identifying polypeptides with improved stability and/or enzymatic activity in comparison to native forms, wherein the identified polypeptides comprise one or more non-natural amino acids. In certain embodiments, the present invention relates to novel phosphotriesterase enzymes comprising one or more non-natural amino acids. In a particular embodiment, the instant invention provides novel phosphotriesterase enzymes with greater stability and/or enhanced activity in comparison to native forms of the enzyme. The present invention also relates to compositions comprising novel phophotriesterase enzymes, such as prophylactics, decontaminants, animal feedstocks, and assay kits.
• US9617525B2
  申请人：——

  公开号：US9617525B2

  公开（公告）日：2017-04-11