申请人:Borbely Janos
公开号:US20050238678A1
公开(公告)日:2005-10-27
Methods are disclosed for preparing linear or/and partial precross-linked poly-g-glutamic acid nanoparticle products, their reaction with compounds which contain vinyl groups, and the polymerization by chemical initiation or photopolymerization of these by light of predetermined wavelength. The final products of the present invention are useful as local drug delivery systems, dental surgery, and for inhibition of post-surgical adhesion. The hydrogels made from the biopolymers of the present invention may also be used in controlled release devices, superabsorbent materials and biomaterials like enzyme immobilization.
本发明揭示了制备线性或/和部分预交联聚-γ-谷氨酸酸纳米颗粒产品的方法,以及它们与含有乙烯基团的化合物发生反应,并通过化学引发或光引发的聚合作用,使用特定波长的光。本发明的最终产品可用作局部药物输送系统、牙科手术以及用于抑制术后粘连。利用本发明的生物聚合物制成的水凝胶还可用于控释器件、超吸水材料和生物材料,如酶固定化。