2,2-Dichloroethyl dimethyl phosphate | 111883-35-3

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 有机磷酸及其衍生物
• 英文名称: 2,2-Dichloroethyl dimethyl phosphate
• CAS: 111883-35-3
• 化学式: C₄H₉Cl₂O₄P
• 分子量: 222.99
• InChiKey: ZYRWHPOKHQYRRQ-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.9
• 重原子数：
  11
• 可旋转键数：
  5
• 环数：
  0.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  44.8
• 氢给体数：
  0
• 氢受体数：
  4

文献信息

• Removal of trimethyl phosphate from phosphorus containing pesticides
  申请人：MOBIL OIL CORPORATION

  公开号：EP0120635A2

  公开（公告）日：1984-10-03

  A single or multi-step water extraction process is described for removing trimethyl phosphate (TMPO) from phosphorous containing pesticides having limited water solubility including 2,2-dichlorovinyl dimethyl phosphate (DDVP), dimethyl CIS-1-methyl-2(1-phenylethoxycarbonyl) vinyl phosphate. 1,2-dibromo - 2,2-dichloroethyl dimethyl phosphate, and trans-2-chloro-1- (2,4,5 - trichlorophenyl) vinyl dimethyl phosphate to a concentration of TMPO less than 1000 ppm. Methanol, dimethyl methylphosphonate, and dimethyl hydrogen phosphite are also removed from the pesticide.

  描述了一种单步或多步水提取工艺，用于从水溶性有限的含磷农药（包括 2,2-二氯乙烯基二甲基磷酸酯（DDVP）、CIS-1-甲基-2(1-苯基乙氧羰基)乙烯基磷酸酯二甲酯）中去除磷酸三甲酯（TMPO）。1,2-二溴-2,2-二氯乙烯基二甲基磷酸酯和反式-2-氯-1-（2,4,5-三氯苯基）乙烯基二甲基磷酸酯的 TMPO 浓度低于 1000 ppm。甲醇、甲基膦酸二甲酯和亚磷酸氢二甲酯也从杀虫剂中去除。
• Novel medication treatment and delivery strategies for Alzheimer's Disease, other disorders with memory impairment, and possible treatment strategies for memory improvement
  申请人：Rabinoff David Michael

  公开号：US20060194723A1

  公开（公告）日：2006-08-31

  The present invention is a novel method for medication treatment for Alzheimer's Disease, Mild Cognitive Impairment, Age Associated Memory Impairment, other disorders with memory impairment, and for possible treatment strategies for memory improvement.

  本发明是一种药物治疗阿尔茨海默氏症、轻度认知障碍、年龄相关性记忆障碍、其他记忆障碍疾病的新方法，以及改善记忆的可能治疗策略。
• US4950658A
  申请人：——

  公开号：US4950658A

  公开（公告）日：1990-08-21
• [EN] METHOD OF MEDICAL TREATMENT OF ALZHEIMER'S DISEASE
  申请人：——

  公开号：WO1990006122A1

  公开（公告）日：1990-06-14

  [FR] L'invention concerne un procédé de traitement de la mémoire et des symptômes constatés chez des patients atteints de la maladie d'Alzheimer et des troubles de la mémoire qui lui sont liés. Le procédé comprend les étapes consistant à administrer à un patient du phosphate de diméthyle 2,2 dichloroéthyle parfois appelé dichlorvos ou DDVP, ou un de ses précurseurs maintenant ledit dosage à un certain niveau pendant une période de temps suffisante pour créer une concentration de DDVP dans le cerveau grâce à quoi on observe une amélioration de la mémoire. Un précurseur satisfaisant pour ce procédé est le phosphate de diméthyle 2,2,2-trichloro-1hydroxyéthyle parfois appelé métrifonate et le phosphate de diméthyle 1, 2-dibromo-, 2-dichloroéthyle parfois appelé naled. D'autres précurseurs sont aussi utiles.
  [EN] This invention relates to a method for improving memory and accompanying symptoms in patients with Alzheimer's disease and related disorders of memory. The method includes the steps of dosing a patient with 2,2-dichloroethyl dimethyl phosphate sometimes referred to as dichlorvos or DDVP, or a precursor thereof maintaining said dosage at a level and over a period of time sufficient to create a concentration of DDVP in the brain whereby memory improvement occurs. A satisfactory precursor for this method is 2,2,2-trichloro-1-hydroxyethyl dimethyl phosphate sometimes referred to as metrifonate and 1,2-dibromo-, 2-dichloroethyl dimethyl phosphate sometimes referred to as naled. Other precursors are also useful.
• [EN] CHEMICAL ATTRACTANTS FOR YELLOWJACKET WASPS<br/>[FR] ATTRACTIFS CHIMIQUES POUR GUEPES
  申请人：US AGRICULTURE

  公开号：WO2003013242A1

  公开（公告）日：2003-02-20

  A combination of volatile components which act synergistically to effectively attract yellowjackets in the Vespula species group is provided. A preferred formulation includes (E)-2-hexenal and linalool in the first component (A) and acetic acid and isobutanol in the second component (B). The two components are combined such that the vapors of the components blend to effectively attract the targeted yellowjackets. A dispenser may be utilized to release the vapors and may also be included within a trap to provide a means for monitoring or controlling the insects.